Squamous cell carcinoma of lung_Lung Tissue_GSE3268 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE3268
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Genes

600 genes differentially expressed during Squamous cell carcinoma of lung_Lung Tissue_GSE3268 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
SNRPC small nuclear ribonucleoprotein polypeptide C 3.8155
AK4 adenylate kinase 4 3.51029
ZC3H3 zinc finger CCCH-type containing 3 3.36823
HAX1 HCLS1 associated protein X-1 3.22047
ARHGAP28 Rho GTPase activating protein 28 2.96116
SFSWAP splicing factor, suppressor of white-apricot family 2.83982
AURKA aurora kinase A 2.83462
C22ORF31 chromosome 22 open reading frame 31 2.83395
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 2.79996
CDK2 cyclin-dependent kinase 2 2.78629
GTPBP10 GTP-binding protein 10 (putative) 2.76077
RACGAP1 Rac GTPase activating protein 1 2.73333
PRIM2 primase, DNA, polypeptide 2 (58kDa) 2.72948
MRPL9 mitochondrial ribosomal protein L9 2.69755
U2AF2 U2 small nuclear RNA auxiliary factor 2 2.68636
BCAS3 breast carcinoma amplified sequence 3 2.68075
SH3GL1 SH3-domain GRB2-like 1 2.65333
CENPA centromere protein A 2.64867
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast) 2.63537
MRPL15 mitochondrial ribosomal protein L15 2.61261
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 2.60889
RND2 Rho family GTPase 2 2.515
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.49608
CCDC85A coiled-coil domain containing 85A 2.49572
NCAPH non-SMC condensin I complex, subunit H 2.47798
CD3EAP CD3e molecule, epsilon associated protein 2.474
TTLL12 tubulin tyrosine ligase-like family member 12 2.45873
RNF5 ring finger protein 5, E3 ubiquitin protein ligase 2.44724
LOC440434 aminopeptidase puromycin sensitive pseudogene 2.44313
TPI1 triosephosphate isomerase 1 2.42139
TRAP1 TNF receptor-associated protein 1 2.42002
SPC25 SPC25, NDC80 kinetochore complex component 2.41424
PRPF31 pre-mRNA processing factor 31 2.39602
RARG retinoic acid receptor, gamma 2.39323
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa 2.38149
VGF VGF nerve growth factor inducible 2.33219
REST RE1-silencing transcription factor 2.32639
FAM64A family with sequence similarity 64, member A 2.32407
CDCA8 cell division cycle associated 8 2.32121
ZNF207 zinc finger protein 207 2.29906
WDR74 WD repeat domain 74 2.27694
LEF1 lymphoid enhancer-binding factor 1 2.2233
PQBP1 polyglutamine binding protein 1 2.21414
CYC1 cytochrome c-1 2.21314
KIFC1 kinesin family member C1 2.19378
PDF peptide deformylase (mitochondrial) 2.17715
CNPY2 canopy FGF signaling regulator 2 2.17067
KRT20 keratin 20, type I 2.16682
RUNX1 runt-related transcription factor 1 2.15809
INHBC inhibin, beta C 2.12276
TGFA transforming growth factor, alpha 2.12218
COPE coatomer protein complex, subunit epsilon 2.11889
B9D1 B9 protein domain 1 2.10522
NIT2 nitrilase family, member 2 2.10372
STMN1 stathmin 1 2.09903
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 2.09397
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa 2.0746
CCT3 chaperonin containing TCP1, subunit 3 (gamma) 2.07227
CENPO centromere protein O 2.06326
MUC8 mucin 8 2.05741
FAM162A family with sequence similarity 162, member A 2.05436
GRM7 glutamate receptor, metabotropic 7 2.04379
A4GALT alpha 1,4-galactosyltransferase 2.01495
LOC441528 zinc finger protein 839-like 2.01425
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 2.01337
DIEXF digestive organ expansion factor homolog (zebrafish) 2.01306
RPL18 ribosomal protein L18 2.00626
HIST1H2AL histone cluster 1, H2al 2.00405
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D 2.00294
UMPS uridine monophosphate synthetase 2.00283
PDE1B phosphodiesterase 1B, calmodulin-dependent 1.99996
TSPAN5 tetraspanin 5 1.99532
PARP2 poly (ADP-ribose) polymerase 2 1.9761
RPP30 ribonuclease P/MRP 30kDa subunit 1.97332
KDM5B lysine (K)-specific demethylase 5B 1.97171
RPL24 ribosomal protein L24 1.97094
TXN2 thioredoxin 2 1.96197
EIF3D eukaryotic translation initiation factor 3, subunit D 1.95505
CARTPT CART prepropeptide 1.95069
CHTOP chromatin target of PRMT1 1.93995
RFWD3 ring finger and WD repeat domain 3 1.93433
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 1.93179
NUP37 nucleoporin 37kDa 1.93132
IGSF3 immunoglobulin superfamily, member 3 1.92001
SIRT5 sirtuin 5 1.91372
RPS15A ribosomal protein S15a 1.90951
GPN1 GPN-loop GTPase 1 1.90925
PRR5 proline rich 5 (renal) 1.90902
ITGB4 integrin, beta 4 1.90011
ITGB8 integrin, beta 8 1.89851
ERGIC3 ERGIC and golgi 3 1.8977
TRIM15 tripartite motif containing 15 1.89715
NUP50 nucleoporin 50kDa 1.89141
HIST1H2AK histone cluster 1, H2ak 1.88804
TSEN34 TSEN34 tRNA splicing endonuclease subunit 1.87412
AURKB aurora kinase B 1.87378
NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa 1.86912
PGK1 phosphoglycerate kinase 1 1.86708
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2 1.86698
SLC4A10 solute carrier family 4, sodium bicarbonate transporter, member 10 1.85514
SNRPA small nuclear ribonucleoprotein polypeptide A 1.84538
EPHA1 EPH receptor A1 1.84072
SHOX2 short stature homeobox 2 1.83587
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 1.83368
DDT D-dopachrome tautomerase 1.82776
AURKAIP1 aurora kinase A interacting protein 1 1.82116
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 1.81785
PTCH1 patched 1 1.8071
MRPL11 mitochondrial ribosomal protein L11 1.80675
MYBPC2 myosin binding protein C, fast type 1.80438
LIG3 ligase III, DNA, ATP-dependent 1.79876
POLG polymerase (DNA directed), gamma 1.79436
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 1.79342
NOP16 NOP16 nucleolar protein 1.79017
CCDC28B coiled-coil domain containing 28B 1.78797
KIAA0087 KIAA0087 1.78526
HIST1H4B histone cluster 1, H4b 1.77937
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase 1.77609
MCHR1 melanin-concentrating hormone receptor 1 1.7687
TSHR thyroid stimulating hormone receptor 1.76171
TRIM17 tripartite motif containing 17 1.76037
ZNF174 zinc finger protein 174 1.75924
NUP155 nucleoporin 155kDa 1.74821
WRAP73 WD repeat containing, antisense to TP73 1.74404
UQCRH ubiquinol-cytochrome c reductase hinge protein 1.73811
PDCD2 programmed cell death 2 1.73486
HMGB3P1 high mobility group box 3 pseudogene 1 1.7344
NF2 neurofibromin 2 (merlin) 1.71915
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa 1.71543
SLC37A2 solute carrier family 37 (glucose-6-phosphate transporter), member 2 1.70438
MKI67 marker of proliferation Ki-67 1.70009
ABI2 abl-interactor 2 1.69794
KIAA1045 KIAA1045 1.68939
DENND6B DENN/MADD domain containing 6B 1.68754
DCTN2 dynactin 2 (p50) 1.687
CENPM centromere protein M 1.68671
SMG9 SMG9 nonsense mediated mRNA decay factor 1.67507
CHPF2 chondroitin polymerizing factor 2 1.67484
ZWILCH zwilch kinetochore protein 1.6656
METTL1 methyltransferase like 1 1.66082
PEX10 peroxisomal biogenesis factor 10 1.65817
ZFP64 ZFP64 zinc finger protein 1.64587
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34 1.64432
SEMG2 semenogelin II 1.64229
C15ORF39 chromosome 15 open reading frame 39 1.63364
IFNA2 interferon, alpha 2 1.63355
NOLC1 nucleolar and coiled-body phosphoprotein 1 1.63288
RAE1 ribonucleic acid export 1 1.62476
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit 1.62307
RPLP0 ribosomal protein, large, P0 1.62062
WDR35 WD repeat domain 35 1.62042
INTS1 integrator complex subunit 1 1.62002
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa 1.61641
AGBL5 ATP/GTP binding protein-like 5 1.6161
VDAC2 voltage-dependent anion channel 2 1.61526
MBD1 methyl-CpG binding domain protein 1 1.61311
TSTA3 tissue specific transplantation antigen P35B 1.60781
SMOX spermine oxidase 1.60592
GFER growth factor, augmenter of liver regeneration 1.60476
NCAPH2 non-SMC condensin II complex, subunit H2 1.60419
PAX6 paired box 6 1.60403
PDIA4 protein disulfide isomerase family A, member 4 1.60058
DTX3 deltex 3, E3 ubiquitin ligase 1.59915
AMH anti-Mullerian hormone 1.59416
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 1.58831
GPR87 G protein-coupled receptor 87 1.58557
KCTD15 potassium channel tetramerization domain containing 15 1.58195
EFNB1 ephrin-B1 1.58125
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) 1.57893
TSSC1 tumor suppressing subtransferable candidate 1 1.57798
CALCA calcitonin-related polypeptide alpha 1.57791
INSR insulin receptor 1.57788
F9 coagulation factor IX 1.56983
PPP4C protein phosphatase 4, catalytic subunit 1.569
RPL41 ribosomal protein L41 1.56568
TUBB tubulin, beta class I 1.5635
ADRM1 adhesion regulating molecule 1 1.56209
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 1.55655
CCNB1 cyclin B1 1.55458
MARK4 MAP/microtubule affinity-regulating kinase 4 1.55228
NRXN2 neurexin 2 1.54815
GTPBP3 GTP binding protein 3 (mitochondrial) 1.54813
NPM3 nucleophosmin/nucleoplasmin 3 1.54736
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 1.54711
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) 1.54686
STARD5 StAR-related lipid transfer (START) domain containing 5 1.54599
RPL37 ribosomal protein L37 1.54002
IMP4 IMP4, U3 small nucleolar ribonucleoprotein 1.53938
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 1.53592
ULBP1 UL16 binding protein 1 1.53498
ETNK2 ethanolamine kinase 2 1.53083
GSK3A glycogen synthase kinase 3 alpha 1.52766
UNC93A unc-93 homolog A (C. elegans) 1.52682
TDP1 tyrosyl-DNA phosphodiesterase 1 1.52666
ACVR2A activin A receptor, type IIA 1.51496
MYF6 myogenic factor 6 (herculin) 1.51365
CIB2 calcium and integrin binding family member 2 1.51248
CDC45 cell division cycle 45 1.51233
FNTB farnesyltransferase, CAAX box, beta 1.5112
SNRPG small nuclear ribonucleoprotein polypeptide G 1.50809
GFRA4 GDNF family receptor alpha 4 1.50598
HTRA2 HtrA serine peptidase 2 1.50456
HIST1H1B histone cluster 1, H1b 1.5032
POU1F1 POU class 1 homeobox 1 1.49489
DPH5 diphthamide biosynthesis 5 1.4933
TCP11L1 t-complex 11, testis-specific-like 1 1.49317
CHEK1 checkpoint kinase 1 1.49178
ELAC2 elaC ribonuclease Z 2 1.4908
ZNF771 zinc finger protein 771 1.48858
SYNJ2 synaptojanin 2 1.48834
NIF3L1 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) 1.48714
LOC389906 zinc finger protein 839 pseudogene 1.48378
SRY sex determining region Y 1.48334
SYT1 synaptotagmin I 1.47706
SFN stratifin 1.47627
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 1.47176
HOMER3 homer scaffolding protein 3 1.47052
PPIH peptidylprolyl isomerase H (cyclophilin H) 1.47039
SSX1 synovial sarcoma, X breakpoint 1 1.46871
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) 1.46678
PTTG1 pituitary tumor-transforming 1 1.46512
EBF2 early B-cell factor 2 1.4638
ZNF212 zinc finger protein 212 1.45821
FAM69A family with sequence similarity 69, member A 1.45742
MRPS18B mitochondrial ribosomal protein S18B 1.4553
C1ORF106 chromosome 1 open reading frame 106 1.45039
CLPTM1 cleft lip and palate associated transmembrane protein 1 1.4502
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 1.44919
PLK1 polo-like kinase 1 1.44844
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha 1.44552
MSTN myostatin 1.44497
ALDH3B2 aldehyde dehydrogenase 3 family, member B2 1.44395
RPS17 ribosomal protein S17 1.44284
UBAP2L ubiquitin associated protein 2-like 1.4416
MYCBP MYC binding protein 1.44023
FGF17 fibroblast growth factor 17 1.43874
EXOSC4 exosome component 4 1.43447
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD) 1.4339
ELANE elastase, neutrophil expressed 1.4331
EHMT2 euchromatic histone-lysine N-methyltransferase 2 1.42722
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 1.42612
SRCAP Snf2-related CREBBP activator protein 1.42218
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 1.42112
DRD4 dopamine receptor D4 1.42009
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 1.41993
KIF4A kinesin family member 4A 1.41812
NXPH4 neurexophilin 4 1.41496
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 1.41406
SCN8A sodium channel, voltage gated, type VIII alpha subunit 1.41334
SPIB Spi-B transcription factor (Spi-1/PU.1 related) 1.41155
CACNB3 calcium channel, voltage-dependent, beta 3 subunit 1.40944
FER1L4 fer-1-like family member 4, pseudogene (functional) 1.40707
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 1.40243
TFG TRK-fused gene 1.4014
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 1.40138
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) 1.40006
PPP2R5D protein phosphatase 2, regulatory subunit B', delta 1.39822
FERMT1 fermitin family member 1 1.39646
BCL7C B-cell CLL/lymphoma 7C 1.39606
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4 1.39512
DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae) 1.39253
CDT1 chromatin licensing and DNA replication factor 1 1.39088
CDC6 cell division cycle 6 1.39016
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker) 1.38774
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 1.38635
PCNAP3 proliferating cell nuclear antigen pseudogene 3 1.3821
TP63 tumor protein p63 1.38208
NCAPG non-SMC condensin I complex, subunit G 1.38094
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) 1.37986
PMPCA peptidase (mitochondrial processing) alpha 1.37766
NHP2 NHP2 ribonucleoprotein 1.37723
STIL SCL/TAL1 interrupting locus 1.37687
KLHL5 kelch-like family member 5 1.372
PTBP1 polypyrimidine tract binding protein 1 1.3691
GINS3 GINS complex subunit 3 (Psf3 homolog) 1.36761
GMPS guanine monphosphate synthase 1.36709
RANBP1 RAN binding protein 1 1.36553
FLAD1 flavin adenine dinucleotide synthetase 1 1.36469
TIPIN TIMELESS interacting protein 1.36463
SLC39A9 solute carrier family 39, member 9 1.36348
SCYL2 SCY1-like 2 (S. cerevisiae) 1.36066
DNAAF5 dynein, axonemal, assembly factor 5 1.35865
CHAF1B chromatin assembly factor 1, subunit B (p60) 1.35608
POU5F1P4 POU class 5 homeobox 1 pseudogene 4 1.35577
OR2W1 olfactory receptor, family 2, subfamily W, member 1 1.35249
DHRS11 dehydrogenase/reductase (SDR family) member 11 1.35064
NR2C2 nuclear receptor subfamily 2, group C, member 2 1.34992
TTPAL tocopherol (alpha) transfer protein-like 1.34925
LRRC41 leucine rich repeat containing 41 1.34884
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.34813
AKT2 v-akt murine thymoma viral oncogene homolog 2 1.34778
ESPN espin 1.3472
CCDC121 coiled-coil domain containing 121 1.34621
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 1.34617
CRHR1 corticotropin releasing hormone receptor 1 1.34303
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.34209
PIAS2 protein inhibitor of activated STAT, 2 1.34092
EIF4E2 eukaryotic translation initiation factor 4E family member 2 1.34028
GRIK2 glutamate receptor, ionotropic, kainate 2 1.33954
SSX3 synovial sarcoma, X breakpoint 3 1.33936

decreased expression

Symbol Name Standardized Value
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) -3.46169
ARRB1 arrestin, beta 1 -3.31253
EVI5 ecotropic viral integration site 5 -3.27121
ID2B inhibitor of DNA binding 2B, dominant negative helix-loop-helix protein (pseudogene) -3.23977
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 -3.22498
DAPK1 death-associated protein kinase 1 -3.15541
ATP10A ATPase, class V, type 10A -3.01201
TMOD1 tropomodulin 1 -2.89415
GLS glutaminase -2.85666
SYNPO2L synaptopodin 2-like -2.83987
MTM1 myotubularin 1 -2.65921
TRIM58 tripartite motif containing 58 -2.65094
AKAP7 A kinase (PRKA) anchor protein 7 -2.65058
AGTPBP1 ATP/GTP binding protein 1 -2.6417
ARHGAP6 Rho GTPase activating protein 6 -2.61481
ARID4A AT rich interactive domain 4A (RBP1-like) -2.45933
F2RL3 coagulation factor II (thrombin) receptor-like 3 -2.41262
TNNC1 troponin C type 1 (slow) -2.39259
PF4V1 platelet factor 4 variant 1 -2.35993
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E -2.34046
CORO2B coronin, actin binding protein, 2B -2.2825
PDE3B phosphodiesterase 3B, cGMP-inhibited -2.28176
DPEP2 dipeptidase 2 -2.2794
ZNF33B zinc finger protein 33B -2.25118
NEK1 NIMA-related kinase 1 -2.25078
FAM105A family with sequence similarity 105, member A -2.21633
FCGRT Fc fragment of IgG, receptor, transporter, alpha -2.2152
MCL1 myeloid cell leukemia 1 -2.21465
FAM63B family with sequence similarity 63, member B -2.15545
VAMP8 vesicle-associated membrane protein 8 -2.14318
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 -2.13902
GPD1L glycerol-3-phosphate dehydrogenase 1-like -2.12638
HSDL2 hydroxysteroid dehydrogenase like 2 -2.12009
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide -2.09997
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) -2.08603
VPS13B vacuolar protein sorting 13 homolog B (yeast) -2.0859
GRK5 G protein-coupled receptor kinase 5 -2.08551
KLHL18 kelch-like family member 18 -2.07497
TNS1 tensin 1 -2.0576
TRPV2 transient receptor potential cation channel, subfamily V, member 2 -2.05129
STX2 syntaxin 2 -2.04295
FBXL15 F-box and leucine-rich repeat protein 15 -2.0418
MADD MAP-kinase activating death domain -2.03608
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 -2.02424
UNC93B1 unc-93 homolog B1 (C. elegans) -2.02214
PIAS1 protein inhibitor of activated STAT, 1 -2.01048
TBC1D4 TBC1 domain family, member 4 -2.00966
DAPK2 death-associated protein kinase 2 -2.00937
STXBP6 syntaxin binding protein 6 (amisyn) -1.99973
CASQ2 calsequestrin 2 (cardiac muscle) -1.99973
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) -1.9966
LONRF3 LON peptidase N-terminal domain and ring finger 3 -1.98822
GATA2 GATA binding protein 2 -1.98114
NCOR1 nuclear receptor corepressor 1 -1.97988
ABR active BCR-related -1.978
LOC1720 dihydrofolate reductase pseudogene -1.97057
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 -1.97007
ADRBK2 adrenergic, beta, receptor kinase 2 -1.96989
TACC1 transforming, acidic coiled-coil containing protein 1 -1.96877
AOX1 aldehyde oxidase 1 -1.96788
GABARAP GABA(A) receptor-associated protein -1.9671
GP5 glycoprotein V (platelet) -1.96692
RBM26 RNA binding motif protein 26 -1.96495
SASH1 SAM and SH3 domain containing 1 -1.95877
INPP5K inositol polyphosphate-5-phosphatase K -1.94283
ZNF204P zinc finger protein 204, pseudogene -1.93767
PDE4D phosphodiesterase 4D, cAMP-specific -1.93715
C2CD2L C2CD2-like -1.93517
CYP2F1 cytochrome P450, family 2, subfamily F, polypeptide 1 -1.93213
TBCD tubulin folding cofactor D -1.9272
AAMDC adipogenesis associated, Mth938 domain containing -1.92428
FIGF c-fos induced growth factor (vascular endothelial growth factor D) -1.91104
SLC5A12 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12 -1.90498
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 -1.90338
BLZF1 basic leucine zipper nuclear factor 1 -1.89991
ZNF44 zinc finger protein 44 -1.8992
FAM134B family with sequence similarity 134, member B -1.89516
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 -1.89005
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 -1.88898
RASSF3 Ras association (RalGDS/AF-6) domain family member 3 -1.88649
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 -1.88
SLC25A31 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31 -1.87652
TMEM35 transmembrane protein 35 -1.87457
TMEM53 transmembrane protein 53 -1.87211
NFX1 nuclear transcription factor, X-box binding 1 -1.86868
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 -1.86821
HEMK1 HemK methyltransferase family member 1 -1.86727
ACACB acetyl-CoA carboxylase beta -1.83473
ARHGAP10 Rho GTPase activating protein 10 -1.83338
A2M alpha-2-macroglobulin -1.83106
B3GNT1 -1.82524
WFDC1 WAP four-disulfide core domain 1 -1.82052
FOXF1 forkhead box F1 -1.81808
DOCK9 dedicator of cytokinesis 9 -1.81611
ARHGAP29 Rho GTPase activating protein 29 -1.80841
ZKSCAN5 zinc finger with KRAB and SCAN domains 5 -1.80468
IQSEC1 IQ motif and Sec7 domain 1 -1.80446
MTRF1L mitochondrial translational release factor 1-like -1.79702
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17 -1.79383
XPC xeroderma pigmentosum, complementation group C -1.79227
LIMCH1 LIM and calponin homology domains 1 -1.78502
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase -1.7786
ESRRG estrogen-related receptor gamma -1.7719
APC adenomatous polyposis coli -1.7712
AFF1 AF4/FMR2 family, member 1 -1.77015
MAP4 microtubule-associated protein 4 -1.76445
NABP1 nucleic acid binding protein 1 -1.76203
TPK1 thiamin pyrophosphokinase 1 -1.76038
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 -1.76
PTPRB protein tyrosine phosphatase, receptor type, B -1.7586
SCN1A sodium channel, voltage gated, type I alpha subunit -1.75384
DLC1 DLC1 Rho GTPase activating protein -1.75178
TRPC2 transient receptor potential cation channel, subfamily C, member 2, pseudogene -1.74993
PRPH2 peripherin 2 (retinal degeneration, slow) -1.74878
FAM189A2 family with sequence similarity 189, member A2 -1.74647
PTPRM protein tyrosine phosphatase, receptor type, M -1.74395
FRMD4B FERM domain containing 4B -1.73982
RAB4B RAB4B, member RAS oncogene family -1.73798
C11ORF30 chromosome 11 open reading frame 30 -1.73681
MKRN3 makorin ring finger protein 3 -1.73597
PDS5B PDS5 cohesin associated factor B -1.72968
EYA1 EYA transcriptional coactivator and phosphatase 1 -1.72378
SMAD6 SMAD family member 6 -1.72267
HAGH hydroxyacylglutathione hydrolase -1.71865
SENP7 SUMO1/sentrin specific peptidase 7 -1.71509
IPCEF1 interaction protein for cytohesin exchange factors 1 -1.71208
MMP24 matrix metallopeptidase 24 (membrane-inserted) -1.70792
ICAM1 intercellular adhesion molecule 1 -1.7024
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -1.69951
TRIP4 thyroid hormone receptor interactor 4 -1.69649
DNMT3L DNA (cytosine-5-)-methyltransferase 3-like -1.69089
ZNF529 zinc finger protein 529 -1.68839
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) -1.685
TMEM100 transmembrane protein 100 -1.68268
CAT catalase -1.68129
ZNF674 zinc finger protein 674 -1.6774
AGER advanced glycosylation end product-specific receptor -1.67258
SCN11A sodium channel, voltage gated, type XI alpha subunit -1.67084
LPIN2 lipin 2 -1.67053
GPHB5 glycoprotein hormone beta 5 -1.66831
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8 -1.66587
CNKSR2 connector enhancer of kinase suppressor of Ras 2 -1.663
CD244 CD244 molecule, natural killer cell receptor 2B4 -1.66233
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) -1.65846
PNPLA2 patatin-like phospholipase domain containing 2 -1.65829
ANO3 anoctamin 3 -1.65278
PLCE1 phospholipase C, epsilon 1 -1.65222
RFX5 regulatory factor X, 5 (influences HLA class II expression) -1.65107
ERG v-ets avian erythroblastosis virus E26 oncogene homolog -1.65021
PDE5A phosphodiesterase 5A, cGMP-specific -1.64901
STOX1 storkhead box 1 -1.64291
SORBS1 sorbin and SH3 domain containing 1 -1.64268
KDM6B lysine (K)-specific demethylase 6B -1.64073
ADGRB3 adhesion G protein-coupled receptor B3 -1.64042
USP32 ubiquitin specific peptidase 32 -1.63704
TCF21 transcription factor 21 -1.63515
MBIP MAP3K12 binding inhibitory protein 1 -1.63447
CAB39 calcium binding protein 39 -1.63142
KBTBD11 kelch repeat and BTB (POZ) domain containing 11 -1.63122
ANGPTL7 angiopoietin-like 7 -1.63065
HS1BP3 HCLS1 binding protein 3 -1.62573
TEK TEK tyrosine kinase, endothelial -1.62345
NPY1R neuropeptide Y receptor Y1 -1.62242
PHKB phosphorylase kinase, beta -1.6204
KIAA1109 KIAA1109 -1.6069
GIN1 gypsy retrotransposon integrase 1 -1.60163
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) -1.60125
BMP2K BMP2 inducible kinase -1.59846
COBL cordon-bleu WH2 repeat protein -1.59752
ELMO2 engulfment and cell motility 2 -1.58075
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -1.57788
RNH1 ribonuclease/angiogenin inhibitor 1 -1.57158
FGF8 fibroblast growth factor 8 (androgen-induced) -1.56932
TCTA T-cell leukemia translocation altered -1.56764
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit -1.56541
TGFB2 transforming growth factor, beta 2 -1.56382
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7 -1.5627
EPHA3 EPH receptor A3 -1.56023
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) -1.55536
SLC25A38 solute carrier family 25, member 38 -1.54995
PTGER4 prostaglandin E receptor 4 (subtype EP4) -1.54696
GVINP1 GTPase, very large interferon inducible pseudogene 1 -1.5467
PDE8A phosphodiesterase 8A -1.54639
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 -1.54278
PCYT2 phosphate cytidylyltransferase 2, ethanolamine -1.54015
PDE8B phosphodiesterase 8B -1.53943
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 -1.53874
BPESC1 blepharophimosis, epicanthus inversus and ptosis, candidate 1 (non-protein coding) -1.53842
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) -1.53747
DPY19L2P2 DPY19L2 pseudogene 2 -1.5365
GPR17 G protein-coupled receptor 17 -1.52987
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -1.52981
TSC1 tuberous sclerosis 1 -1.52765
TBC1D2B TBC1 domain family, member 2B -1.52443
SLC19A1 solute carrier family 19 (folate transporter), member 1 -1.52273
DOCK10 dedicator of cytokinesis 10 -1.5174
FAM66D family with sequence similarity 66, member D -1.51461
QKI QKI, KH domain containing, RNA binding -1.51151
RHOB ras homolog family member B -1.50187
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 -1.50128
BCAP29 B-cell receptor-associated protein 29 -1.50098
RPL23AP22 ribosomal protein L23a pseudogene 22 -1.49947
STOM stomatin -1.49299
SYNJ1 synaptojanin 1 -1.49114
DCT dopachrome tautomerase -1.49033
TCAF1 TRPM8 channel-associated factor 1 -1.49025
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) -1.48673
STAC SH3 and cysteine rich domain -1.4859
B3GALT2 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 -1.48529
LAT2 linker for activation of T cells family, member 2 -1.48509
PRKCA protein kinase C, alpha -1.47879
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene -1.47486
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like -1.47414
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -1.47235
RFPL1 ret finger protein-like 1 -1.4722
DIXDC1 DIX domain containing 1 -1.47184
CTSO cathepsin O -1.467
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) -1.46668
SELP selectin P (granule membrane protein 140kDa, antigen CD62) -1.46282
DIRAS3 DIRAS family, GTP-binding RAS-like 3 -1.45961
CRY2 cryptochrome circadian clock 2 -1.4594
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 -1.45522
RNF185 ring finger protein 185 -1.45456
CEP170 centrosomal protein 170kDa -1.45173
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) -1.4502
CTSD cathepsin D -1.44992
TSPAN15 tetraspanin 15 -1.44977
GATA6 GATA binding protein 6 -1.44759
ETV1 ets variant 1 -1.4464
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 -1.44452
VCL vinculin -1.44448
TTR transthyretin -1.44374
KIF5C kinesin family member 5C -1.43863
ZPBP zona pellucida binding protein -1.43794
POU2F3 POU class 2 homeobox 3 -1.43762
HYAL2 hyaluronoglucosaminidase 2 -1.43489
AGBL3 ATP/GTP binding protein-like 3 -1.43484
TLL1 tolloid-like 1 -1.43088
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -1.42765
SETD3 SET domain containing 3 -1.4265
PCDHA2 protocadherin alpha 2 -1.42589
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -1.4255
LINC00472 long intergenic non-protein coding RNA 472 -1.42517
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2 -1.4248
DMP1 dentin matrix acidic phosphoprotein 1 -1.42371
PKNOX2 PBX/knotted 1 homeobox 2 -1.42363
THSD1 thrombospondin, type I, domain containing 1 -1.42336
IL7 interleukin 7 -1.42008
SNX5 sorting nexin 5 -1.41983
C8A complement component 8, alpha polypeptide -1.4184
EPB41L1 erythrocyte membrane protein band 4.1-like 1 -1.41757
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 -1.41493
PBRM1 polybromo 1 -1.41382
RAB11FIP2 RAB11 family interacting protein 2 (class I) -1.41378
FRY furry homolog (Drosophila) -1.41254
CD302 CD302 molecule -1.4116
OR11A1 olfactory receptor, family 11, subfamily A, member 1 -1.40946
TRIM3 tripartite motif containing 3 -1.40936
SPAG9 sperm associated antigen 9 -1.40878
ACR acrosin -1.40656
KANK1 KN motif and ankyrin repeat domains 1 -1.40504
ZMYND11 zinc finger, MYND-type containing 11 -1.40365
ITSN1 intersectin 1 (SH3 domain protein) -1.40275
AZI2 5-azacytidine induced 2 -1.40251
KIAA0895 KIAA0895 -1.40208
MAP7D3 MAP7 domain containing 3 -1.40117
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1 -1.3998
ADGRF5 adhesion G protein-coupled receptor F5 -1.39878
TAOK2 TAO kinase 2 -1.39571
ARHGAP24 Rho GTPase activating protein 24 -1.3957
ENG endoglin -1.39551
SERTAD3 SERTA domain containing 3 -1.39402
BLVRA biliverdin reductase A -1.39279
SESN1 sestrin 1 -1.39053
SECISBP2L SECIS binding protein 2-like -1.39048
KCTD7 potassium channel tetramerization domain containing 7 -1.38807
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) -1.38506
LRRN3 leucine rich repeat neuronal 3 -1.38147
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 -1.38096
LDB2 LIM domain binding 2 -1.37857
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2 -1.37739
PTPN21 protein tyrosine phosphatase, non-receptor type 21 -1.37635
PDS5A PDS5 cohesin associated factor A -1.37629
RAB11FIP3 RAB11 family interacting protein 3 (class II) -1.37542
STX3 syntaxin 3 -1.37503
FBXO38 F-box protein 38 -1.37469
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -1.37351
SEPT11 septin 11 -1.37312
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 -1.3729
DRD2 dopamine receptor D2 -1.37136
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 -1.36916
HBBP1 hemoglobin, beta pseudogene 1 -1.36815
ADGRG6 adhesion G protein-coupled receptor G6 -1.36542
CAMTA2 calmodulin binding transcription activator 2 -1.36291
UHRF1BP1L UHRF1 binding protein 1-like -1.36192
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 -1.36136
GIPC3 GIPC PDZ domain containing family, member 3 -1.35784
C9ORF156 chromosome 9 open reading frame 156 -1.35753
SAMD4A sterile alpha motif domain containing 4A -1.35747
FNBP1 formin binding protein 1 -1.35662
Funding