Stereocilium Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores 2025
Category structural or functional annotations
Type cellular component
Description An actin-based protrusion from the apical surface of auditory and vestibular hair cells. Bundles of stereocilia act as mechanosensory organelles. (Gene Ontology, GO_0032420)
External Link http://amigo.geneontology.org/amigo/term/GO:0032420
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Genes

40 proteins localized to the Stereocilium cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.

Symbol Name Standardized Value
CIB2 calcium and integrin binding family member 2 5.0
STRC stereocilin 4.0
TMC2 transmembrane channel-like 2 4.0
STX4 syntaxin 4 4.0
EPS8 epidermal growth factor receptor pathway substrate 8 4.0
ESPN espin 4.0
KPTN kaptin (actin binding protein) 4.0
HOMER2 homer scaffolding protein 2 4.0
EPS8L2 EPS8-like 2 4.0
ANKRD24 ankyrin repeat domain 24 4.0
MYO3A myosin IIIA 4.0
MYO7A myosin VIIA 4.0
TPRN taperin 4.0
GRXCR1 glutaredoxin, cysteine rich 1 4.0
PTPRQ protein tyrosine phosphatase, receptor type, Q 4.0
RDX radixin 4.0
RIPOR2 RHO family interacting cell polarization regulator 2 4.0
TMC1 transmembrane channel-like 1 4.0
TSPEAR thrombospondin-type laminin G domain and EAR repeats 4.0
RHOC ras homolog family member C 4.0
ESPNL espin-like 4.0
LOXHD1 lipoxygenase homology domains 1 4.0
FCHSD2 FCH and double SH3 domains 2 4.0
MORN4 MORN repeat containing 4 4.0
MYO3B myosin IIIB 4.0
CEACAM16 carcinoembryonic antigen-related cell adhesion molecule 16 4.0
WHRN whirlin 4.0
CDC14A cell division cycle 14A 4.0
PIEZO1 piezo-type mechanosensitive ion channel component 1 4.0
PIEZO2 piezo-type mechanosensitive ion channel component 2 4.0
PLS1 plastin 1 4.0
CDH23 cadherin-related 23 3.0
USH1C Usher syndrome 1C (autosomal recessive, severe) 3.0
GRXCR2 glutaredoxin, cysteine rich 2 3.0
PCDH15 protocadherin-related 15 3.0
DOCK4 dedicator of cytokinesis 4 3.0
PDZD7 PDZ domain containing 7 3.0
ADGRV1 adhesion G protein-coupled receptor V1 3.0
USH2A Usher syndrome 2A (autosomal recessive, mild) 3.0
TWF2 twinfilin actin binding protein 2 3.0