Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C3658302
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Genes

50 genes associated with the disease Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALB albumin
BAG6 BCL2-associated athanogene 6
CAV1 caveolin 1, caveolae protein, 22kDa
CCL17 chemokine (C-C motif) ligand 17
CCL22 chemokine (C-C motif) ligand 22
CCL27 chemokine (C-C motif) ligand 27
CELF2 CUGBP, Elav-like family member 2
COPS5 COP9 signalosome subunit 5
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CSF3 colony stimulating factor 3 (granulocyte)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CUL1 cullin 1
CUL4A cullin 4A
DERL1 derlin 1
ELMO1 engulfment and cell motility 1
EP300 E1A binding protein p300
FBXO6 F-box protein 6
FDXR ferredoxin reductase
GRAP2 GRB2-related adaptor protein 2
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HSPG2 heparan sulfate proteoglycan 2
IFNA2 interferon, alpha 2
IFNG interferon, gamma
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL15 interleukin 15
IL17A interleukin 17A
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
NOS2 nitric oxide synthase 2, inducible
NUCB1 nucleobindin 1
PARP1 poly (ADP-ribose) polymerase 1
PML promyelocytic leukemia
POLDIP2 polymerase (DNA-directed), delta interacting protein 2
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTGIS prostaglandin I2 (prostacyclin) synthase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RB1 retinoblastoma 1
RBX1 ring-box 1, E3 ubiquitin protein ligase
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
TNF tumor necrosis factor
VCP valosin containing protein