| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| Description | A sulfonamide in which the sulfamoyl functional group is attached to aniline at the 4-position. (Chemical Entities of Biological Interest Ontology, CHEBI_45373) |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/5333 |
| Similar Terms | |
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199 proteins with high or low expression in Sulfanilamide relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MDM1 | Mdm1 nuclear protein homolog (mouse) | 1.1 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | 0.98 |
| ABHD18 | abhydrolase domain containing 18 | 0.89 |
| NES | nestin | 0.82 |
| RNF185 | ring finger protein 185 | 0.78 |
| ADCY10 | adenylate cyclase 10 (soluble) | 0.75 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.72 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.67 |
| RPS26 | ribosomal protein S26 | 0.49 |
| ZC3H12A | zinc finger CCCH-type containing 12A | 0.46 |
| GAS8 | growth arrest-specific 8 | 0.46 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.45 |
| POLE4 | polymerase (DNA-directed), epsilon 4, accessory subunit | 0.45 |
| PLPP6 | phospholipid phosphatase 6 | 0.45 |
| TXNDC15 | thioredoxin domain containing 15 | 0.44 |
| PCBD1 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha | 0.42 |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 | 0.42 |
| POLH | polymerase (DNA directed), eta | 0.41 |
| HMBOX1 | homeobox containing 1 | 0.41 |
| DENND4B | DENN/MADD domain containing 4B | 0.41 |
| KLHL24 | kelch-like family member 24 | 0.41 |
| TBC1D14 | TBC1 domain family, member 14 | 0.41 |
| WHAMM | WAS protein homolog associated with actin, golgi membranes and microtubules | 0.39 |
| MIB2 | mindbomb E3 ubiquitin protein ligase 2 | 0.39 |
| RGL2 | ral guanine nucleotide dissociation stimulator-like 2 | 0.37 |
| MCRIP2 | MAPK regulated corepressor interacting protein 2 | 0.35 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.34 |
| SLX4 | SLX4 structure-specific endonuclease subunit | 0.34 |
| ALG14 | ALG14, UDP-N-acetylglucosaminyltransferase subunit | 0.34 |
| PLEKHG4 | pleckstrin homology domain containing, family G (with RhoGef domain) member 4 | 0.34 |
| HIKESHI | heat shock protein nuclear import factor hikeshi | 0.33 |
| BTBD11 | BTB (POZ) domain containing 11 | 0.33 |
| LZTS1 | leucine zipper, putative tumor suppressor 1 | 0.33 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.31 |
| SPATA2 | spermatogenesis associated 2 | 0.3 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.29 |
| C19ORF54 | chromosome 19 open reading frame 54 | 0.29 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.29 |
| RUNDC1 | RUN domain containing 1 | 0.29 |
| SLC38A7 | solute carrier family 38, member 7 | 0.29 |
| ZNF165 | zinc finger protein 165 | 0.29 |
| ZNF776 | zinc finger protein 776 | 0.29 |
| XTBD1 | XRN2 binding domain containing 1 | 0.28 |
| PRPF40B | PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae) | 0.28 |
| RNF170 | ring finger protein 170 | 0.28 |
| C6ORF47 | chromosome 6 open reading frame 47 | 0.28 |
| PCGF3 | polycomb group ring finger 3 | 0.28 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 | 0.28 |
| ZNF597 | zinc finger protein 597 | 0.28 |
| RBL2 | retinoblastoma-like 2 | 0.27 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | 0.27 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 | 0.27 |
| ARHGAP23 | Rho GTPase activating protein 23 | 0.27 |
| USP30 | ubiquitin specific peptidase 30 | 0.27 |
| RASSF3 | Ras association (RalGDS/AF-6) domain family member 3 | 0.27 |
| FAM171A1 | family with sequence similarity 171, member A1 | 0.26 |
| CARD10 | caspase recruitment domain family, member 10 | 0.26 |
| HYPK | huntingtin interacting protein K | 0.26 |
| SGSM3 | small G protein signaling modulator 3 | 0.26 |
| YBX3 | Y box binding protein 3 | 0.25 |
| GPR180 | G protein-coupled receptor 180 | 0.25 |
| FLCN | folliculin | 0.25 |
| TNS2 | tensin 2 | 0.25 |
| ZNF618 | zinc finger protein 618 | 0.25 |
| LTBP3 | latent transforming growth factor beta binding protein 3 | 0.25 |
| POLR2K | polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa | 0.25 |
| PNKD | paroxysmal nonkinesigenic dyskinesia | 0.25 |
| ATP9B | ATPase, class II, type 9B | 0.25 |
| AKAP6 | A kinase (PRKA) anchor protein 6 | 0.25 |
| RIN3 | Ras and Rab interactor 3 | 0.25 |
| TBC1D22B | TBC1 domain family, member 22B | 0.24 |
| RFTN1 | raftlin, lipid raft linker 1 | 0.24 |
| KLK6 | kallikrein-related peptidase 6 | 0.24 |
| CSNK1A1L | casein kinase 1, alpha 1-like | 0.24 |
| MYH3 | myosin, heavy chain 3, skeletal muscle, embryonic | 0.24 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.24 |
| PTPRU | protein tyrosine phosphatase, receptor type, U | 0.24 |
| CDCA3 | cell division cycle associated 3 | 0.24 |
| CAMKK1 | calcium/calmodulin-dependent protein kinase kinase 1, alpha | 0.24 |
| UNC13D | unc-13 homolog D (C. elegans) | 0.24 |
| CPN1 | carboxypeptidase N, polypeptide 1 | 0.23 |
| DMD | dystrophin | 0.23 |
| CREBZF | CREB/ATF bZIP transcription factor | 0.23 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.23 |
| GPN2 | GPN-loop GTPase 2 | 0.23 |
| COA6 | cytochrome c oxidase assembly factor 6 | 0.23 |
| SDC1 | syndecan 1 | 0.23 |
| INO80D | INO80 complex subunit D | 0.23 |
| STK17A | serine/threonine kinase 17a | 0.23 |
| PTEN | phosphatase and tensin homolog | 0.23 |
| ZFAND1 | zinc finger, AN1-type domain 1 | 0.23 |
| MADD | MAP-kinase activating death domain | 0.23 |
| DNLZ | DNL-type zinc finger | 0.22 |
| GLT8D1 | glycosyltransferase 8 domain containing 1 | 0.22 |
| BRPF3 | bromodomain and PHD finger containing, 3 | 0.22 |
| ZNF525 | zinc finger protein 525 | 0.22 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.22 |
| ATOX1 | antioxidant 1 copper chaperone | 0.22 |
| CEP112 | centrosomal protein 112kDa | 0.22 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H | 0.22 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PRSS23 | protease, serine, 23 | -0.79 |
| FZD3 | frizzled class receptor 3 | -0.77 |
| PTK2B | protein tyrosine kinase 2 beta | -0.74 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.57 |
| HLA-F | major histocompatibility complex, class I, F | -0.55 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -0.54 |
| ARAP2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 | -0.47 |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit | -0.47 |
| TSC22D2 | TSC22 domain family, member 2 | -0.46 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | -0.46 |
| LANCL3 | LanC lantibiotic synthetase component C-like 3 (bacterial) | -0.41 |
| ANAPC11 | anaphase promoting complex subunit 11 | -0.41 |
| SRD5A3 | steroid 5 alpha-reductase 3 | -0.38 |
| TPCN1 | two pore segment channel 1 | -0.38 |
| ADGRL1 | adhesion G protein-coupled receptor L1 | -0.38 |
| TDG | thymine-DNA glycosylase | -0.37 |
| SNX15 | sorting nexin 15 | -0.36 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.35 |
| ZNF414 | zinc finger protein 414 | -0.35 |
| KCTD17 | potassium channel tetramerization domain containing 17 | -0.35 |
| KIAA0930 | KIAA0930 | -0.35 |
| RGP1 | RGP1 retrograde golgi transport homolog (S. cerevisiae) | -0.35 |
| GGACT | gamma-glutamylamine cyclotransferase | -0.34 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D | -0.34 |
| ZNF771 | zinc finger protein 771 | -0.34 |
| MTRF1 | mitochondrial translational release factor 1 | -0.34 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 | -0.33 |
| AKNA | AT-hook transcription factor | -0.33 |
| EVL | Enah/Vasp-like | -0.33 |
| LDB1 | LIM domain binding 1 | -0.32 |
| MITD1 | MIT, microtubule interacting and transport, domain containing 1 | -0.31 |
| XPA | xeroderma pigmentosum, complementation group A | -0.31 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.31 |
| ATXN7L1 | ataxin 7-like 1 | -0.31 |
| TTC39B | tetratricopeptide repeat domain 39B | -0.3 |
| GLRX5 | glutaredoxin 5 | -0.3 |
| CPE | carboxypeptidase E | -0.3 |
| GRB14 | growth factor receptor-bound protein 14 | -0.29 |
| CCDC110 | coiled-coil domain containing 110 | -0.29 |
| TM7SF3 | transmembrane 7 superfamily member 3 | -0.29 |
| MTFP1 | mitochondrial fission process 1 | -0.29 |
| NAA80 | N-alpha-acetyltransferase 80, NatH catalytic subunit | -0.29 |
| GRK5 | G protein-coupled receptor kinase 5 | -0.28 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.28 |
| KMT5C | lysine methyltransferase 5C | -0.28 |
| ATG2A | autophagy related 2A | -0.28 |
| HYKK | hydroxylysine kinase | -0.28 |
| VCPKMT | valosin containing protein lysine (K) methyltransferase | -0.28 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.28 |
| KCTD14 | potassium channel tetramerization domain containing 14 | -0.28 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | -0.28 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.28 |
| B4GAT1 | beta-1,4-glucuronyltransferase 1 | -0.27 |
| TADA2A | transcriptional adaptor 2A | -0.27 |
| PPP1R16A | protein phosphatase 1, regulatory subunit 16A | -0.27 |
| DISP2 | dispatched homolog 2 (Drosophila) | -0.27 |
| TM7SF2 | transmembrane 7 superfamily member 2 | -0.27 |
| SLC25A4 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 | -0.27 |
| CSNK1G2 | casein kinase 1, gamma 2 | -0.26 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.26 |
| PIH1D1 | PIH1 domain containing 1 | -0.26 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | -0.26 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.26 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 | -0.26 |
| HSP90AA4P | heat shock protein 90kDa alpha (cytosolic), class A member 4, pseudogene | -0.26 |
| SP110 | SP110 nuclear body protein | -0.25 |
| DUSP7 | dual specificity phosphatase 7 | -0.25 |
| FAM102A | family with sequence similarity 102, member A | -0.25 |
| TMEM179B | transmembrane protein 179B | -0.25 |
| ZFYVE26 | zinc finger, FYVE domain containing 26 | -0.25 |
| RGPD8 | RANBP2-like and GRIP domain containing 8 | -0.25 |
| FBXL15 | F-box and leucine-rich repeat protein 15 | -0.25 |
| PCDH1 | protocadherin 1 | -0.25 |
| FAM234B | family with sequence similarity 234 member B | -0.25 |
| SF1 | splicing factor 1 | -0.25 |
| ERO1B | endoplasmic reticulum oxidoreductase 1 beta | -0.25 |
| PPP1R11 | protein phosphatase 1, regulatory (inhibitor) subunit 11 | -0.25 |
| ZNF672 | zinc finger protein 672 | -0.25 |
| CDK18 | cyclin-dependent kinase 18 | -0.25 |
| ANKRD13D | ankyrin repeat domain 13 family, member D | -0.25 |
| CADM4 | cell adhesion molecule 4 | -0.24 |
| COX5B | cytochrome c oxidase subunit Vb | -0.24 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.24 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.24 |
| ZNF805 | zinc finger protein 805 | -0.24 |
| ZDHHC8 | zinc finger, DHHC-type containing 8 | -0.24 |
| CRYM | crystallin, mu | -0.24 |
| MRPL33 | mitochondrial ribosomal protein L33 | -0.24 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | -0.24 |
| TIGD2 | tigger transposable element derived 2 | -0.24 |
| LGMN | legumain | -0.23 |
| GAS2L3 | growth arrest-specific 2 like 3 | -0.23 |
| MIGA2 | mitoguardin 2 | -0.23 |
| MICB | MHC class I polypeptide-related sequence B | -0.23 |
| ISCA2 | iron-sulfur cluster assembly 2 | -0.23 |
| TSPAN15 | tetraspanin 15 | -0.23 |
| PXMP4 | peroxisomal membrane protein 4, 24kDa | -0.23 |
| HSBP1 | heat shock factor binding protein 1 | -0.23 |
| APEX2 | APEX nuclease (apurinic/apyrimidinic endonuclease) 2 | -0.22 |
