| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sulfatinib perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sulfatinib_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.142742 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.130667 |
| AHNAK | AHNAK nucleoprotein | 0.0863177 |
| FBN1 | fibrillin 1 | 0.0818804 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0715809 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0626575 |
| SQSTM1 | sequestosome 1 | 0.0590702 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0567017 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0544804 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0534636 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0466683 |
| GOLGA4 | golgin A4 | 0.045782 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0444868 |
| FTL | ferritin, light polypeptide | 0.0440358 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0427338 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0386365 |
| INSIG1 | insulin induced gene 1 | 0.0379856 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0379242 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0368339 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0341478 |
| MEIS2 | Meis homeobox 2 | 0.033427 |
| CANX | calnexin | 0.03315 |
| DST | dystonin | 0.0327276 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0319167 |
| CD109 | CD109 molecule | 0.0306803 |
| PTMA | prothymosin, alpha | 0.0303514 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0283063 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0276996 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0276838 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | 0.0271189 |
| RND3 | Rho family GTPase 3 | 0.0266272 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0261035 |
| FNIP1 | folliculin interacting protein 1 | 0.025601 |
| MSI2 | musashi RNA-binding protein 2 | 0.0254901 |
| C1D | C1D nuclear receptor corepressor | 0.0254272 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0249667 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0242754 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.0239972 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0238338 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0230402 |
| MMP12 | matrix metallopeptidase 12 | 0.0227542 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0226511 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0226509 |
| LOXL2 | lysyl oxidase-like 2 | 0.0224215 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0219124 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0218095 |
| ENO1 | enolase 1, (alpha) | 0.0212958 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0212907 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0212803 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0210092 |
| ADM | adrenomedullin | 0.0205448 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0203215 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0201675 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0199231 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0198535 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0198385 |
| GDF15 | growth differentiation factor 15 | 0.0196276 |
| RPL35A | ribosomal protein L35a | 0.0195037 |
| HSPB1 | heat shock 27kDa protein 1 | 0.0194244 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0192698 |
| GASK1B | golgi associated kinase 1B | 0.0191268 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0191027 |
| CCNL1 | cyclin L1 | 0.0189708 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0186052 |
| RNF169 | ring finger protein 169 | 0.018602 |
| IRF1 | interferon regulatory factor 1 | 0.0185316 |
| GOLGA2 | golgin A2 | 0.0183723 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.0183464 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0181166 |
| WDR43 | WD repeat domain 43 | 0.0180748 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.0179068 |
| TOX | thymocyte selection-associated high mobility group box | 0.0178018 |
| WTAP | Wilms tumor 1 associated protein | 0.0177527 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0176803 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0176511 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0174402 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0174176 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 | 0.0174144 |
| RPS6 | ribosomal protein S6 | 0.017235 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.0168479 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0167157 |
| OGA | O-GlcNAcase | 0.0164017 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0163978 |
| NEFL | neurofilament, light polypeptide | 0.0163136 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 0.0160652 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0160033 |
| AUTS2 | autism susceptibility candidate 2 | 0.0159896 |
| PCGF5 | polycomb group ring finger 5 | 0.0159742 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0159494 |
| TNS3 | tensin 3 | 0.0158923 |
| RAB18 | RAB18, member RAS oncogene family | 0.0158907 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0158858 |
| KIFAP3 | kinesin-associated protein 3 | 0.0157452 |
| BRD4 | bromodomain containing 4 | 0.0156982 |
| MYOF | myoferlin | 0.0156728 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0155338 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0154861 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | 0.015417 |
| FMNL2 | formin-like 2 | 0.0153651 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0152545 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PLAT | plasminogen activator, tissue | -0.257432 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.25466 |
| MT2A | metallothionein 2A | -0.203816 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.201552 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.162629 |
| VIM | vimentin | -0.152452 |
| LOX | lysyl oxidase | -0.136232 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.13181 |
| CD44 | CD44 molecule (Indian blood group) | -0.126432 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.110327 |
| NDRG1 | N-myc downstream regulated 1 | -0.0901724 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.085615 |
| NAV1 | neuron navigator 1 | -0.0793385 |
| TMSB10 | thymosin beta 10 | -0.0768994 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0751461 |
| STC1 | stanniocalcin 1 | -0.072336 |
| PODXL | podocalyxin-like | -0.0700815 |
| MAP1B | microtubule-associated protein 1B | -0.0659735 |
| FLNB | filamin B, beta | -0.0626058 |
| RUNX1 | runt-related transcription factor 1 | -0.0583396 |
| MYADM | myeloid-associated differentiation marker | -0.0560675 |
| S100A10 | S100 calcium binding protein A10 | -0.0560199 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0513674 |
| MT1X | metallothionein 1X | -0.0505626 |
| SVIL | supervillin | -0.0502363 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0501212 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0479281 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0448893 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0445087 |
| GLIS3 | GLIS family zinc finger 3 | -0.0434372 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0432661 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0417696 |
| TMSB4X | thymosin beta 4, X-linked | -0.0413255 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0411844 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0401362 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0390997 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0382641 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0369189 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0361562 |
| TAGLN2 | transgelin 2 | -0.0360526 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0358847 |
| FN1 | fibronectin 1 | -0.0351028 |
| EFNA5 | ephrin-A5 | -0.0350982 |
| PRSS23 | protease, serine, 23 | -0.0349749 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0332253 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0332124 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0329113 |
| COL5A2 | collagen, type V, alpha 2 | -0.0323626 |
| CD99 | CD99 molecule | -0.0316776 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0315927 |
| CTSB | cathepsin B | -0.030955 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0309214 |
| OSMR | oncostatin M receptor | -0.0306254 |
| MYO9B | myosin IXB | -0.0305674 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0304398 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0303939 |
| COL5A1 | collagen, type V, alpha 1 | -0.0298729 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0296964 |
| RASA2 | RAS p21 protein activator 2 | -0.0295893 |
| NAV2 | neuron navigator 2 | -0.0291183 |
| SP3 | Sp3 transcription factor | -0.0284504 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0283595 |
| CLTC | clathrin, heavy chain (Hc) | -0.0277224 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0276523 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0275586 |
| MTSS1 | metastasis suppressor 1 | -0.0272852 |
| SMYD3 | SET and MYND domain containing 3 | -0.0272328 |
| FSTL1 | follistatin-like 1 | -0.0270582 |
| ANXA2 | annexin A2 | -0.0269325 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.0269067 |
| SEPTIN7 | septin 7 | -0.026829 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0266394 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0264141 |
| CEP170 | centrosomal protein 170kDa | -0.0262819 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0260422 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0259979 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0257142 |
| DNMBP | dynamin binding protein | -0.0256431 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.0256105 |
| CYTH3 | cytohesin 3 | -0.0255862 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0255546 |
| BPTF | bromodomain PHD finger transcription factor | -0.0254474 |
| DGKG | diacylglycerol kinase, gamma 90kDa | -0.0254277 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0254216 |
| HIP1 | huntingtin interacting protein 1 | -0.0252824 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0251544 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0251308 |
| SEPTIN9 | septin 9 | -0.0250777 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0250523 |
| LOC112694756 | uncharaterized LOC112694756 | -0.024794 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0246843 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.024614 |
| MPZL1 | myelin protein zero-like 1 | -0.0244557 |
| MSN | moesin | -0.0244064 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0240239 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0239469 |
| ANLN | anillin, actin binding protein | -0.0239228 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0237351 |
| MAP4 | microtubule-associated protein 4 | -0.0236618 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0235745 |
