| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sulfatinib perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sulfatinib_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.251121 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.120725 |
| NLGN1 | neuroligin 1 | 0.105495 |
| YAP1 | Yes-associated protein 1 | 0.102075 |
| MMP12 | matrix metallopeptidase 12 | 0.08649 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.082636 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0767606 |
| TENM3 | teneurin transmembrane protein 3 | 0.0765062 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0748962 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.07158 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.070051 |
| PDGFC | platelet derived growth factor C | 0.0674664 |
| TMSB10 | thymosin beta 10 | 0.0673881 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0655386 |
| DST | dystonin | 0.063536 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0549628 |
| TXNRD1 | thioredoxin reductase 1 | 0.0545418 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0535883 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0525969 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0505136 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0487508 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0485549 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0482715 |
| RPS19 | ribosomal protein S19 | 0.0482526 |
| EPHA6 | EPH receptor A6 | 0.0469095 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.045239 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0445969 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | 0.0429059 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0428897 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0412064 |
| RRM2 | ribonucleotide reductase M2 | 0.0400766 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0398039 |
| AHNAK | AHNAK nucleoprotein | 0.039534 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 0.0390915 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.0387859 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0386988 |
| MKI67 | marker of proliferation Ki-67 | 0.0385141 |
| WWOX | WW domain containing oxidoreductase | 0.0381752 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0374649 |
| NEK7 | NIMA-related kinase 7 | 0.0369428 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0367883 |
| CPOX | coproporphyrinogen oxidase | 0.0364028 |
| ECT2 | epithelial cell transforming 2 | 0.0363148 |
| YBX1 | Y box binding protein 1 | 0.0356742 |
| ASPH | aspartate beta-hydroxylase | 0.0352998 |
| RPL9 | ribosomal protein L9 | 0.0342362 |
| MTAP | methylthioadenosine phosphorylase | 0.0341205 |
| GASK1B | golgi associated kinase 1B | 0.0338524 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0335108 |
| RTN4 | reticulon 4 | 0.0332299 |
| ATP11A | ATPase, class VI, type 11A | 0.0322277 |
| RPLP1 | ribosomal protein, large, P1 | 0.0317671 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0317185 |
| PCDH7 | protocadherin 7 | 0.03147 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0313285 |
| CLTC | clathrin, heavy chain (Hc) | 0.0309572 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0308844 |
| RPS27A | ribosomal protein S27a | 0.0308162 |
| CANX | calnexin | 0.03048 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0303676 |
| YBX3 | Y box binding protein 3 | 0.0303426 |
| RPS12 | ribosomal protein S12 | 0.0302744 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0301921 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0300548 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.029742 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0297375 |
| HDAC9 | histone deacetylase 9 | 0.029569 |
| TNPO1 | transportin 1 | 0.0293991 |
| RPS21 | ribosomal protein S21 | 0.0287015 |
| GOLGB1 | golgin B1 | 0.0286981 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.028649 |
| RACK1 | receptor for activated C kinase 1 | 0.0285014 |
| ANKRD36 | ankyrin repeat domain 36 | 0.028374 |
| MSH6 | mutS homolog 6 | 0.0283445 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0279586 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0279373 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0279096 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0277434 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.0276462 |
| RPS6 | ribosomal protein S6 | 0.0275184 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0274759 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0268717 |
| MED13L | mediator complex subunit 13-like | 0.0267369 |
| EPHA5 | EPH receptor A5 | 0.0267317 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0264541 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0261352 |
| RPS23 | ribosomal protein S23 | 0.0259525 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | 0.0258905 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0258207 |
| NEGR1 | neuronal growth regulator 1 | 0.0257831 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0257774 |
| RPL19 | ribosomal protein L19 | 0.0256351 |
| CCNL1 | cyclin L1 | 0.0255797 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0252459 |
| RPL23 | ribosomal protein L23 | 0.0251495 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0250478 |
| NBAS | neuroblastoma amplified sequence | 0.0249882 |
| ETNK1 | ethanolamine kinase 1 | 0.0248636 |
| RPL4 | ribosomal protein L4 | 0.0247892 |
| RPL11 | ribosomal protein L11 | 0.0247701 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.120841 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.11262 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0809502 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0718253 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0505411 |
| HMGA1 | high mobility group AT-hook 1 | -0.0502774 |
| TPI1 | triosephosphate isomerase 1 | -0.046396 |
| S100A6 | S100 calcium binding protein A6 | -0.0436618 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0435777 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.042971 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0413902 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0412124 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0399577 |
| PFN1 | profilin 1 | -0.0397842 |
| SLC38A1 | solute carrier family 38, member 1 | -0.03939 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0381385 |
| EHBP1 | EH domain binding protein 1 | -0.0377032 |
| USP34 | ubiquitin specific peptidase 34 | -0.0375787 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0367291 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0367143 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0365837 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | -0.0352411 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0346212 |
| TUBA1B | tubulin, alpha 1b | -0.0333414 |
| PTMA | prothymosin, alpha | -0.0329916 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0329517 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0329353 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0326749 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0318219 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0314806 |
| ACTG1 | actin gamma 1 | -0.0308208 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0303621 |
| RASAL2 | RAS protein activator like 2 | -0.0302789 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0298258 |
| NF1 | neurofibromin 1 | -0.0292359 |
| TMEM123 | transmembrane protein 123 | -0.0281071 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.027363 |
| GCG | glucagon | -0.0263852 |
| EGR1 | early growth response 1 | -0.0252825 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0248602 |
| ATXN2 | ataxin 2 | -0.0248111 |
| VPS8 | vacuolar protein sorting 8 homolog (S. cerevisiae) | -0.0246463 |
| MTREX | Mtr4 exosome RNA helicase | -0.0246383 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0238836 |
| CLDN1 | claudin 1 | -0.0233066 |
| AREG | amphiregulin | -0.0225857 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0220229 |
| UBE4B | ubiquitination factor E4B | -0.0219291 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0217847 |
| TMEM47 | transmembrane protein 47 | -0.0215544 |
| EGFR | epidermal growth factor receptor | -0.0214595 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.020975 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0207734 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0205364 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0205192 |
| TSPAN5 | tetraspanin 5 | -0.0202267 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0201473 |
| HMGA2 | high mobility group AT-hook 2 | -0.0200437 |
| KSR2 | kinase suppressor of ras 2 | -0.0199755 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0199427 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0199166 |
| SESN2 | sestrin 2 | -0.0199122 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0194241 |
| SSH2 | slingshot protein phosphatase 2 | -0.0193408 |
| AARS1 | alanyl-tRNA synthetase 1 | -0.0192916 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0190432 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0190001 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0189046 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0188942 |
| PKM | pyruvate kinase, muscle | -0.0188231 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0186537 |
| RAP1GDS1 | RAP1, GTP-GDP dissociation stimulator 1 | -0.0186221 |
| FAM162A | family with sequence similarity 162, member A | -0.0186087 |
| VAT1 | vesicle amine transport 1 | -0.0185393 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.018363 |
| TM9SF4 | transmembrane 9 superfamily protein member 4 | -0.0183562 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0176802 |
| SETD2 | SET domain containing 2 | -0.0174641 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0174216 |
| RHOA | ras homolog family member A | -0.0173859 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0172387 |
| GPHN | gephyrin | -0.0171962 |
| S100A11 | S100 calcium binding protein A11 | -0.0169956 |
| WWC1 | WW and C2 domain containing 1 | -0.0169188 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.01663 |
| S100A10 | S100 calcium binding protein A10 | -0.0166052 |
| BRI3BP | BRI3 binding protein | -0.0165181 |
| TPM4 | tropomyosin 4 | -0.016426 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0164254 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | -0.0164132 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | -0.0163513 |
| H1-0 | H1.0 linker histone | -0.0162575 |
| SPAG9 | sperm associated antigen 9 | -0.0160926 |
| MLF2 | myeloid leukemia factor 2 | -0.0160909 |
| SLC39A11 | solute carrier family 39, member 11 | -0.016073 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0160079 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0159121 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0157728 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0157317 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.0157038 |
