Sulfatinib_COLO 205 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Sulfatinib perturbation in COLO 205 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Sulfatinib_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
BTBD9 BTB (POZ) domain containing 9 0.102555
MBNL2 muscleblind-like splicing regulator 2 0.0693474
FNDC3B fibronectin type III domain containing 3B 0.0640987
GMDS GDP-mannose 4,6-dehydratase 0.0605276
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.0603622
PHF3 PHD finger protein 3 0.0553876
ARHGAP26 Rho GTPase activating protein 26 0.0520692
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 0.051597
STK39 serine threonine kinase 39 0.0515119
TRIO trio Rho guanine nucleotide exchange factor 0.0490929
SYNE2 spectrin repeat containing, nuclear envelope 2 0.0446334
PRKCA protein kinase C, alpha 0.0424602
GOLGB1 golgin B1 0.0420539
UBAC2 UBA domain containing 2 0.0396636
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.0373448
RAD51B RAD51 paralog B 0.0370098
FNIP1 folliculin interacting protein 1 0.0365319
BCLAF1 BCL2-associated transcription factor 1 0.0357218
IGF1R insulin-like growth factor 1 receptor 0.0343635
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) 0.0341575
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.033012
RBM26 RNA binding motif protein 26 0.032921
MYH9 myosin, heavy chain 9, non-muscle 0.0324479
ABHD2 abhydrolase domain containing 2 0.0305562
NPSR1 neuropeptide S receptor 1 0.0304129
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked 0.0302285
PRELID2 PRELI domain containing 2 0.0298078
STS steroid sulfatase (microsomal), isozyme S 0.0295498
MCTP2 multiple C2 domains, transmembrane 2 0.0290943
RABGAP1L RAB GTPase activating protein 1-like 0.0282748
SORBS1 sorbin and SH3 domain containing 1 0.0280779
KIF16B kinesin family member 16B 0.0278474
MSI2 musashi RNA-binding protein 2 0.0275884
SAMD4A sterile alpha motif domain containing 4A 0.0275382
SPATA13 spermatogenesis associated 13 0.027504
DSCAM Down syndrome cell adhesion molecule 0.0274723
NCOA2 nuclear receptor coactivator 2 0.0264658
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38 0.0263064
PCCA propionyl CoA carboxylase, alpha polypeptide 0.0259667
ANKRD10 ankyrin repeat domain 10 0.0256421
SMAD3 SMAD family member 3 0.0252905
CANX calnexin 0.0252592
NKD1 naked cuticle homolog 1 (Drosophila) 0.0249932
PTEN phosphatase and tensin homolog 0.0247044
FAT1 FAT atypical cadherin 1 0.0244929
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.0244444
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 0.0243253
IFNGR1 interferon gamma receptor 1 0.0240107
MYO10 myosin X 0.0239061
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.0235229
MLPH melanophilin 0.0234297
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 0.0234141
ATXN1 ataxin 1 0.023241
ATP11A ATPase, class VI, type 11A 0.0231158
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0228623
PTK2 protein tyrosine kinase 2 0.022705
PUM2 pumilio RNA-binding family member 2 0.0226453
COG6 component of oligomeric golgi complex 6 0.0221836
TAS2R14 taste receptor, type 2, member 14 0.0218829
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 0.0214679
EGLN3 egl-9 family hypoxia-inducible factor 3 0.0214075
MECOM MDS1 and EVI1 complex locus 0.0207135
USP53 ubiquitin specific peptidase 53 0.0207037
TBC1D22A TBC1 domain family, member 22A 0.0206161
PHC3 polyhomeotic homolog 3 (Drosophila) 0.0205194
HDAC4 histone deacetylase 4 0.0204462
LCORL ligand dependent nuclear receptor corepressor-like 0.0203928
ZMYM2 zinc finger, MYM-type 2 0.0200443
PARP14 poly (ADP-ribose) polymerase family, member 14 0.0199027
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 0.0198275
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.0196774
ARHGAP32 Rho GTPase activating protein 32 0.0195873
KDM4C lysine (K)-specific demethylase 4C 0.0195691
ZNF148 zinc finger protein 148 0.019359
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 0.0192745
LPP LIM domain containing preferred translocation partner in lipoma 0.0191375
DSCAML1 Down syndrome cell adhesion molecule like 1 0.0187879
BICRAL BICRA like chromatin remodeling complex associated protein 0.0186593
AFF1 AF4/FMR2 family, member 1 0.0182988
SRSF1 serine/arginine-rich splicing factor 1 0.0178539
TMEM39A transmembrane protein 39A 0.017803
MBD5 methyl-CpG binding domain protein 5 0.0177326
SYNGAP1 synaptic Ras GTPase activating protein 1 0.0177006
MAML2 mastermind-like 2 (Drosophila) 0.0175903
SLC22A23 solute carrier family 22, member 23 0.0175237
SEC24D SEC24 family member D 0.0174679
FNDC3A fibronectin type III domain containing 3A 0.0172418
KDM6A lysine (K)-specific demethylase 6A 0.0172258
CLTC clathrin, heavy chain (Hc) 0.0166969
GSK3B glycogen synthase kinase 3 beta 0.0164073
ZNRF3 zinc and ring finger 3 0.0162942
SAMD12 sterile alpha motif domain containing 12 0.016262
NUMB numb homolog (Drosophila) 0.0161785
HELZ helicase with zinc finger 0.0158328
CCDC146 coiled-coil domain containing 146 0.0157958
AUH AU RNA binding protein/enoyl-CoA hydratase 0.01579
ZFC3H1 zinc finger, C3H1-type containing 0.0157876
COPA coatomer protein complex, subunit alpha 0.015771
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.0157573
ALPK1 alpha-kinase 1 0.0156989

decreased expression

Symbol Name Standardized Value
B2M beta-2-microglobulin -0.235034
TPT1 tumor protein, translationally-controlled 1 -0.232789
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.189959
LCN2 lipocalin 2 -0.175003
HLA-B major histocompatibility complex, class I, B -0.156886
IFI6 interferon, alpha-inducible protein 6 -0.103337
FTL ferritin, light polypeptide -0.101914
RPS6 ribosomal protein S6 -0.100671
RPL35A ribosomal protein L35a -0.0940266
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0913259
TMSB10 thymosin beta 10 -0.0860824
RPLP1 ribosomal protein, large, P1 -0.0783581
PTMA prothymosin, alpha -0.0781535
EGR1 early growth response 1 -0.0743618
MT2A metallothionein 2A -0.0733431
RPL23 ribosomal protein L23 -0.0728211
EIF1 eukaryotic translation initiation factor 1 -0.0693291
IFI27 interferon, alpha-inducible protein 27 -0.0672764
RPS19 ribosomal protein S19 -0.0638856
S100A10 S100 calcium binding protein A10 -0.0629352
RPL12 ribosomal protein L12 -0.0627545
C6ORF132 chromosome 6 open reading frame 132 -0.0625888
RPS8 ribosomal protein S8 -0.0618843
PERP PERP, TP53 apoptosis effector -0.061232
PKM pyruvate kinase, muscle -0.0610536
HLA-C major histocompatibility complex, class I, C -0.0602241
RPL19 ribosomal protein L19 -0.0582679
LOC102724023 ES1 protein homolog, mitochondrial -0.0560799
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) -0.054584
RPL34 ribosomal protein L34 -0.0509125
RPL11 ribosomal protein L11 -0.0502123
NDRG1 N-myc downstream regulated 1 -0.0494991
SLC38A1 solute carrier family 38, member 1 -0.0484003
MYO1E myosin IE -0.0482739
HLA-A major histocompatibility complex, class I, A -0.0482024
RPL26 ribosomal protein L26 -0.0480301
RPL37 ribosomal protein L37 -0.0457906
RPL37A ribosomal protein L37a -0.0453174
LOC112694756 uncharaterized LOC112694756 -0.0447872
RPS27 ribosomal protein S27 -0.0446007
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0445459
RPL31 ribosomal protein L31 -0.0433895
RPLP0 ribosomal protein, large, P0 -0.0432814
CSTB cystatin B (stefin B) -0.0418264
RPL28 ribosomal protein L28 -0.0416109
ACTG1 actin gamma 1 -0.0400237
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0389816
RPS3 ribosomal protein S3 -0.0389459
RPS24 ribosomal protein S24 -0.0382182
DSTN destrin (actin depolymerizing factor) -0.0376465
MT1X metallothionein 1X -0.0376306
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0375456
RPS13 ribosomal protein S13 -0.0371082
IFITM3 interferon induced transmembrane protein 3 -0.0369775
RPL38 ribosomal protein L38 -0.0364655
RPLP2 ribosomal protein, large, P2 -0.0363664
H3-3B H3.3 histone B -0.03631
ANXA2 annexin A2 -0.0358423
S100A9 S100 calcium binding protein A9 -0.0358035
RPL18 ribosomal protein L18 -0.0353852
CST3 cystatin C -0.0351852
RPS23 ribosomal protein S23 -0.034878
S100A6 S100 calcium binding protein A6 -0.034599
RPS29 ribosomal protein S29 -0.0344692
AREG amphiregulin -0.0343051
RPS11 ribosomal protein S11 -0.0340532
RPL30 ribosomal protein L30 -0.0338519
RPS20 ribosomal protein S20 -0.0338441
HLA-E major histocompatibility complex, class I, E -0.0336529
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -0.0334171
UQCRB ubiquinol-cytochrome c reductase binding protein -0.0331327
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0321961
RPS14 ribosomal protein S14 -0.0319637
CLDN4 claudin 4 -0.0315627
ENO1 enolase 1, (alpha) -0.0314955
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 -0.0313425
RPS27A ribosomal protein S27a -0.0309703
GNAS GNAS complex locus -0.0309187
RPL32 ribosomal protein L32 -0.0303865
RPL8 ribosomal protein L8 -0.0303832
ISG15 ISG15 ubiquitin-like modifier -0.0301803
RPS25 ribosomal protein S25 -0.0301279
HMGB1 high mobility group box 1 -0.0301171
S100P S100 calcium binding protein P -0.0300552
VDAC1 voltage-dependent anion channel 1 -0.0298608
RPL36A ribosomal protein L36a -0.0298546
RPS12 ribosomal protein S12 -0.0296604
RPS17 ribosomal protein S17 -0.0292405
KLF6 Kruppel-like factor 6 -0.0285687
RPL35 ribosomal protein L35 -0.0284414
TPI1 triosephosphate isomerase 1 -0.0284319
RRBP1 ribosome binding protein 1 -0.0283609
RPS16 ribosomal protein S16 -0.0282879
POMP proteasome maturation protein -0.0282793
IRF1 interferon regulatory factor 1 -0.0281044
CALR calreticulin -0.0277433
WSB1 WD repeat and SOCS box containing 1 -0.0275774
RPL9 ribosomal protein L9 -0.027164
TMC5 transmembrane channel-like 5 -0.0270796
CALM2 calmodulin 2 (phosphorylase kinase, delta) -0.0268721