| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sulfatinib perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sulfatinib_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MTSS1 | metastasis suppressor 1 | 0.196337 |
| MEF2A | myocyte enhancer factor 2A | 0.179174 |
| ENO1 | enolase 1, (alpha) | 0.115818 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.113999 |
| RAI14 | retinoic acid induced 14 | 0.105968 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0954652 |
| ASPH | aspartate beta-hydroxylase | 0.0926771 |
| ITGA6 | integrin, alpha 6 | 0.0923584 |
| FLNB | filamin B, beta | 0.0897064 |
| MSN | moesin | 0.0885129 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0882332 |
| CLU | clusterin | 0.086496 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0814578 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0790691 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0773361 |
| KIAA1217 | KIAA1217 | 0.0744051 |
| FNIP1 | folliculin interacting protein 1 | 0.0700322 |
| PTK2 | protein tyrosine kinase 2 | 0.0698845 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0682905 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0680944 |
| SLK | STE20-like kinase | 0.0676847 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0650803 |
| ZNF292 | zinc finger protein 292 | 0.0637412 |
| GOLGA4 | golgin A4 | 0.0614006 |
| TPM3 | tropomyosin 3 | 0.0603807 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0588111 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0586731 |
| PGK1 | phosphoglycerate kinase 1 | 0.0586043 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0585825 |
| NAV2 | neuron navigator 2 | 0.0584318 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0579773 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0573125 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0570219 |
| TGM2 | transglutaminase 2 | 0.0547293 |
| SULF1 | sulfatase 1 | 0.0532678 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0527298 |
| MYOF | myoferlin | 0.052489 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0522192 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0512075 |
| PRELID2 | PRELI domain containing 2 | 0.0507357 |
| OGA | O-GlcNAcase | 0.0502513 |
| NCOR2 | nuclear receptor corepressor 2 | 0.048398 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0472979 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0464502 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0459074 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0446341 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.044549 |
| EZR | ezrin | 0.0430816 |
| PODXL | podocalyxin-like | 0.0427197 |
| CANX | calnexin | 0.0421536 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0416999 |
| MYO10 | myosin X | 0.0414537 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.0405921 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0404294 |
| TOP1 | topoisomerase (DNA) I | 0.0401993 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0401554 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0401 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0400468 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0396979 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.039657 |
| TMF1 | TATA element modulatory factor 1 | 0.0396101 |
| SUCO | SUN domain containing ossification factor | 0.0392601 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0390538 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0383844 |
| FAM13A | family with sequence similarity 13, member A | 0.0382479 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0380198 |
| KRT17 | keratin 17, type I | 0.0379445 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0376407 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0373101 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0372948 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | 0.0371269 |
| PTMA | prothymosin, alpha | 0.0368444 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.036758 |
| XPO1 | exportin 1 | 0.0365485 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0362197 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0357062 |
| ANLN | anillin, actin binding protein | 0.0356079 |
| YEATS2 | YEATS domain containing 2 | 0.0353747 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.035191 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0349959 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0349236 |
| ANXA5 | annexin A5 | 0.0348855 |
| ARRDC3 | arrestin domain containing 3 | 0.03487 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0339859 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0339272 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0337059 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0336854 |
| DIDO1 | death inducer-obliterator 1 | 0.0330558 |
| RNF145 | ring finger protein 145 | 0.0329309 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0328006 |
| ANXA1 | annexin A1 | 0.032782 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0324539 |
| YAP1 | Yes-associated protein 1 | 0.0323452 |
| RPL3 | ribosomal protein L3 | 0.0323262 |
| DSTN | destrin (actin depolymerizing factor) | 0.0319844 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 0.031963 |
| RIN2 | Ras and Rab interactor 2 | 0.0319272 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0317778 |
| KRT6A | keratin 6A, type II | 0.0314435 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0313042 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.190799 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0997069 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0741374 |
| TMSB10 | thymosin beta 10 | -0.0656172 |
| S100A10 | S100 calcium binding protein A10 | -0.0641917 |
| INTS6 | integrator complex subunit 6 | -0.0582559 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0510039 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0503239 |
| RIGI | RNA sensor RIG-I | -0.0478755 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0473321 |
| FOXO1 | forkhead box O1 | -0.0470631 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0464862 |
| OSMR | oncostatin M receptor | -0.0442768 |
| PALLD | palladin, cytoskeletal associated protein | -0.0425857 |
| VCL | vinculin | -0.0422306 |
| SULF2 | sulfatase 2 | -0.0388806 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0387099 |
| EGR1 | early growth response 1 | -0.03734 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0351733 |
| RPS24 | ribosomal protein S24 | -0.0328831 |
| RASAL2 | RAS protein activator like 2 | -0.0325403 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0319568 |
| MT2A | metallothionein 2A | -0.031516 |
| CD44 | CD44 molecule (Indian blood group) | -0.0314248 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0313791 |
| GNAS | GNAS complex locus | -0.0312286 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0306236 |
| PITPNB | phosphatidylinositol transfer protein, beta | -0.0305571 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0303333 |
| FOXP1 | forkhead box P1 | -0.0303203 |
| MT1X | metallothionein 1X | -0.0302718 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0296341 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0294335 |
| AOPEP | aminopeptidase O (putative) | -0.028203 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.0277531 |
| TMSB4X | thymosin beta 4, X-linked | -0.0275831 |
| LMO7 | LIM domain 7 | -0.0271712 |
| ARF1 | ADP-ribosylation factor 1 | -0.0269528 |
| CAVIN1 | caveolae associated protein 1 | -0.0266217 |
| CORO2A | coronin, actin binding protein, 2A | -0.0262705 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0260964 |
| NDRG1 | N-myc downstream regulated 1 | -0.0260878 |
| ACTG1 | actin gamma 1 | -0.0256657 |
| RPS4X | ribosomal protein S4, X-linked | -0.025031 |
| ACTN4 | actinin, alpha 4 | -0.0250203 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0249556 |
| FN1 | fibronectin 1 | -0.0247079 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0246709 |
| DUSP6 | dual specificity phosphatase 6 | -0.0245838 |
| FBXO11 | F-box protein 11 | -0.0244726 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0241151 |
| RPL35A | ribosomal protein L35a | -0.0237718 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0237646 |
| HLA-B | major histocompatibility complex, class I, B | -0.0236203 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0235629 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0235086 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0230079 |
| THBD | thrombomodulin | -0.0228253 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.022397 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0221229 |
| TJP1 | tight junction protein 1 | -0.0221074 |
| RPLP0 | ribosomal protein, large, P0 | -0.0220183 |
| RPL27A | ribosomal protein L27a | -0.0219565 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0217275 |
| RPLP1 | ribosomal protein, large, P1 | -0.0216731 |
| EGFR | epidermal growth factor receptor | -0.0214009 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0212989 |
| MEIS2 | Meis homeobox 2 | -0.021224 |
| DGKH | diacylglycerol kinase, eta | -0.0210097 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0209396 |
| PLSCR1 | phospholipid scramblase 1 | -0.0204401 |
| S100A6 | S100 calcium binding protein A6 | -0.0204324 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0204069 |
| RPS20 | ribosomal protein S20 | -0.0203496 |
| MECOM | MDS1 and EVI1 complex locus | -0.0202168 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | -0.0199982 |
| S100A4 | S100 calcium binding protein A4 | -0.0197576 |
| CNTNAP3 | contactin associated protein-like 3 | -0.0196469 |
| RPL34 | ribosomal protein L34 | -0.0195925 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.019419 |
| RPL36A | ribosomal protein L36a | -0.0193166 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.0193064 |
| RAB31 | RAB31, member RAS oncogene family | -0.0192669 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0191921 |
| RPS21 | ribosomal protein S21 | -0.0190606 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0187499 |
| S100A11 | S100 calcium binding protein A11 | -0.0186093 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0185324 |
| SETX | senataxin | -0.0183246 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.018274 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0181075 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0180024 |
| HM13 | histocompatibility (minor) 13 | -0.017784 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.0177293 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | -0.0175492 |
| OXSR1 | oxidative stress responsive 1 | -0.0175271 |
| OGFR | opioid growth factor receptor | -0.0175009 |
| GM2A | GM2 ganglioside activator | -0.0174166 |
| RPL39 | ribosomal protein L39 | -0.0173582 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0170998 |
