| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sulfatinib perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Sulfatinib_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.151067 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.105673 |
| TXNRD1 | thioredoxin reductase 1 | 0.0735146 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.052124 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0517875 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0449771 |
| SPAG9 | sperm associated antigen 9 | 0.043856 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0422505 |
| CANX | calnexin | 0.0368068 |
| OGA | O-GlcNAcase | 0.0366101 |
| RTN4 | reticulon 4 | 0.0355975 |
| NUP58 | nucleoporin 58 | 0.0349209 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0344603 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0338943 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0330257 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0317063 |
| EZR | ezrin | 0.0314765 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0314714 |
| RBM39 | RNA binding motif protein 39 | 0.0307589 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0304487 |
| JMJD1C | jumonji domain containing 1C | 0.0302117 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0291945 |
| AHNAK | AHNAK nucleoprotein | 0.028666 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0275095 |
| ANKRD11 | ankyrin repeat domain 11 | 0.026396 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0260767 |
| TOP1 | topoisomerase (DNA) I | 0.0256499 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0256268 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0255196 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0252002 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0251165 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0245881 |
| CENPF | centromere protein F, 350/400kDa | 0.0240702 |
| ECT2 | epithelial cell transforming 2 | 0.023976 |
| ANLN | anillin, actin binding protein | 0.0238332 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0237166 |
| TFRC | transferrin receptor | 0.023366 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0233187 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0232254 |
| RNF145 | ring finger protein 145 | 0.0227788 |
| WDR43 | WD repeat domain 43 | 0.0227192 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0226475 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0224316 |
| MATR3 | matrin 3 | 0.0222271 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0217467 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0214917 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0213717 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0211505 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0209643 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0208465 |
| QKI | QKI, KH domain containing, RNA binding | 0.0206961 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0205588 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0204969 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0203489 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0202398 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0200237 |
| FNIP1 | folliculin interacting protein 1 | 0.0200135 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0199421 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0198744 |
| TFG | TRK-fused gene | 0.0196471 |
| CLTC | clathrin, heavy chain (Hc) | 0.0196149 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0196117 |
| SBF2 | SET binding factor 2 | 0.0195511 |
| CDC73 | cell division cycle 73 | 0.0195017 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0193587 |
| RLF | rearranged L-myc fusion | 0.0192045 |
| NBAS | neuroblastoma amplified sequence | 0.0191331 |
| FOXJ3 | forkhead box J3 | 0.0186942 |
| TMEM41B | transmembrane protein 41B | 0.0186395 |
| ANXA1 | annexin A1 | 0.0186203 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0182033 |
| WDR26 | WD repeat domain 26 | 0.018198 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0180548 |
| WDR45B | WD repeat domain 45B | 0.0180113 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0180047 |
| CUL3 | cullin 3 | 0.0179951 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0179155 |
| NCKAP1 | NCK-associated protein 1 | 0.0179064 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0178498 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0177133 |
| TNPO1 | transportin 1 | 0.0175563 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0175218 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0174214 |
| RBM33 | RNA binding motif protein 33 | 0.0173659 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0172905 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0172252 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0171886 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0171192 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0169779 |
| MEMO1 | mediator of cell motility 1 | 0.0169398 |
| ZNF292 | zinc finger protein 292 | 0.0169303 |
| NUP153 | nucleoporin 153kDa | 0.0168687 |
| UBQLN1 | ubiquilin 1 | 0.016818 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0167621 |
| ARRDC3 | arrestin domain containing 3 | 0.0166504 |
| XPO1 | exportin 1 | 0.0166062 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0166058 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0165704 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0164875 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.0164784 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.312708 |
| MT2A | metallothionein 2A | -0.21312 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.203844 |
| TP63 | tumor protein p63 | -0.178621 |
| TMSB10 | thymosin beta 10 | -0.13011 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.128643 |
| CD44 | CD44 molecule (Indian blood group) | -0.109539 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.104845 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.097276 |
| PTMA | prothymosin, alpha | -0.091066 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0908905 |
| HLA-B | major histocompatibility complex, class I, B | -0.0871465 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0800697 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0668886 |
| CADM2 | cell adhesion molecule 2 | -0.0658795 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0654976 |
| RPS19 | ribosomal protein S19 | -0.0646654 |
| POTEF | POTE ankyrin domain family, member F | -0.0642069 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0568133 |
| MT1E | metallothionein 1E | -0.0549183 |
| FTL | ferritin, light polypeptide | -0.0530215 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0516704 |
| RPL12 | ribosomal protein L12 | -0.050209 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0499234 |
| RPS8 | ribosomal protein S8 | -0.0499171 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0494415 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0491614 |
| EHBP1 | EH domain binding protein 1 | -0.0486872 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0467488 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.046377 |
| RNF213 | ring finger protein 213 | -0.0463326 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0459775 |
| RPL36 | ribosomal protein L36 | -0.0457284 |
| RPS6 | ribosomal protein S6 | -0.0445437 |
| RIGI | RNA sensor RIG-I | -0.0440738 |
| TNS3 | tensin 3 | -0.0433067 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0421583 |
| HMGA1 | high mobility group AT-hook 1 | -0.0409867 |
| DST | dystonin | -0.0408245 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.040486 |
| RPS12 | ribosomal protein S12 | -0.0402991 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0401534 |
| RUNX1 | runt-related transcription factor 1 | -0.0393499 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0392592 |
| RPL23 | ribosomal protein L23 | -0.0390353 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0388079 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0386846 |
| HLA-A | major histocompatibility complex, class I, A | -0.0366124 |
| PDE10A | phosphodiesterase 10A | -0.0365401 |
| SP100 | SP100 nuclear antigen | -0.0363786 |
| DNER | delta/notch-like EGF repeat containing | -0.036357 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0360791 |
| TMSB4X | thymosin beta 4, X-linked | -0.0360179 |
| PLSCR1 | phospholipid scramblase 1 | -0.0358161 |
| RPL35A | ribosomal protein L35a | -0.035816 |
| B2M | beta-2-microglobulin | -0.0354808 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0349753 |
| RPL31 | ribosomal protein L31 | -0.0349542 |
| EGR1 | early growth response 1 | -0.034263 |
| RPL35 | ribosomal protein L35 | -0.0340418 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0338641 |
| RAD51B | RAD51 paralog B | -0.0335597 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0333934 |
| RPL37A | ribosomal protein L37a | -0.0331483 |
| RPLP2 | ribosomal protein, large, P2 | -0.0328435 |
| MT1X | metallothionein 1X | -0.0324451 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0301447 |
| RPLP1 | ribosomal protein, large, P1 | -0.0298562 |
| TGM2 | transglutaminase 2 | -0.0295931 |
| EPHA4 | EPH receptor A4 | -0.0295199 |
| RPL37 | ribosomal protein L37 | -0.0291651 |
| RPL28 | ribosomal protein L28 | -0.0291222 |
| ECE1 | endothelin converting enzyme 1 | -0.0288368 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0288186 |
| COL5A2 | collagen, type V, alpha 2 | -0.0288161 |
| ACTG1 | actin gamma 1 | -0.028732 |
| HDAC9 | histone deacetylase 9 | -0.028406 |
| RPS27 | ribosomal protein S27 | -0.0280557 |
| CMIP | c-Maf inducing protein | -0.028036 |
| RPL26 | ribosomal protein L26 | -0.0280043 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0276222 |
| ANGPTL4 | angiopoietin-like 4 | -0.0271992 |
| RPL19 | ribosomal protein L19 | -0.0271882 |
| S100A9 | S100 calcium binding protein A9 | -0.027146 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | -0.0270654 |
| SRGN | serglycin | -0.0269103 |
| PMP22 | peripheral myelin protein 22 | -0.0268047 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0267217 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0266869 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0265839 |
| RPS23 | ribosomal protein S23 | -0.0265606 |
| RPL8 | ribosomal protein L8 | -0.0265133 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0262103 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0261019 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0259919 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.025723 |
| RPS29 | ribosomal protein S29 | -0.0256312 |
| PFN1 | profilin 1 | -0.0253273 |
| PRELID2 | PRELI domain containing 2 | -0.0252879 |
| RPS14 | ribosomal protein S14 | -0.0252046 |
