| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sulfatinib perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Sulfatinib_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CES1 | carboxylesterase 1 | 0.0929133 |
| LAMC2 | laminin, gamma 2 | 0.0869413 |
| SLTM | SAFB-like, transcription modulator | 0.0858961 |
| EGFR | epidermal growth factor receptor | 0.0819024 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0775855 |
| NGLY1 | N-glycanase 1 | 0.0742868 |
| RUNX1 | runt-related transcription factor 1 | 0.0591972 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0577606 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0553551 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0547632 |
| OSMR | oncostatin M receptor | 0.0533743 |
| MKI67 | marker of proliferation Ki-67 | 0.0528113 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 0.0499945 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0481053 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0464664 |
| LAMA4 | laminin, alpha 4 | 0.0458536 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0456937 |
| H1-0 | H1.0 linker histone | 0.04459 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0441236 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.042182 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0418878 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0417795 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0413561 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0406816 |
| OGA | O-GlcNAcase | 0.0405843 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0402554 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0397879 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0393609 |
| TXNRD1 | thioredoxin reductase 1 | 0.0388032 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0360994 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0348115 |
| WDR26 | WD repeat domain 26 | 0.034082 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0340133 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0339941 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0339876 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0332365 |
| RTN4 | reticulon 4 | 0.0325387 |
| RASA2 | RAS p21 protein activator 2 | 0.032308 |
| ANO6 | anoctamin 6 | 0.0321245 |
| KIAA1217 | KIAA1217 | 0.0317482 |
| GPATCH2L | G patch domain containing 2-like | 0.0310127 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0308751 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0306731 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0305856 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0301833 |
| LAMB3 | laminin, beta 3 | 0.0296851 |
| PGK1 | phosphoglycerate kinase 1 | 0.0296167 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0292056 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0291823 |
| MARF1 | meiosis regulator and mRNA stability factor 1 | 0.0288174 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0287404 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0278079 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0277528 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0276139 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0274579 |
| RNF169 | ring finger protein 169 | 0.0273512 |
| MYO1B | myosin IB | 0.0271159 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0271021 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0270948 |
| JMJD1C | jumonji domain containing 1C | 0.0267702 |
| ASPH | aspartate beta-hydroxylase | 0.0266542 |
| YEATS2 | YEATS domain containing 2 | 0.0264779 |
| ZBTB1 | zinc finger and BTB domain containing 1 | 0.026443 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0263795 |
| USP34 | ubiquitin specific peptidase 34 | 0.0263574 |
| EP300 | E1A binding protein p300 | 0.0263398 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0262833 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0259194 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0257862 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0254049 |
| LRP12 | low density lipoprotein receptor-related protein 12 | 0.025397 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0253637 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0252784 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0251502 |
| SEPTIN10 | septin 10 | 0.024859 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.02478 |
| KLC1 | kinesin light chain 1 | 0.0247487 |
| PLEC | plectin | 0.0244567 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0244375 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0243559 |
| ATP13A3 | ATPase type 13A3 | 0.0243387 |
| TMF1 | TATA element modulatory factor 1 | 0.0243148 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0241206 |
| PRELID2 | PRELI domain containing 2 | 0.0236561 |
| NEK7 | NIMA-related kinase 7 | 0.0236165 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0235233 |
| METTL15 | methyltransferase like 15 | 0.0234927 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0234582 |
| SP3 | Sp3 transcription factor | 0.023455 |
| FNIP1 | folliculin interacting protein 1 | 0.0234516 |
| KIAA1328 | KIAA1328 | 0.0232504 |
| FAT1 | FAT atypical cadherin 1 | 0.0231551 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0230507 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0229357 |
| GPC6 | glypican 6 | 0.0226428 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.022602 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0224902 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.022489 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0224552 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0223773 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.332405 |
| TMSB10 | thymosin beta 10 | -0.149902 |
| NDRG1 | N-myc downstream regulated 1 | -0.116839 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0894193 |
| FTL | ferritin, light polypeptide | -0.0854116 |
| EGR1 | early growth response 1 | -0.0841029 |
| S100A10 | S100 calcium binding protein A10 | -0.0833592 |
| ACTG1 | actin gamma 1 | -0.0776555 |
| PTMA | prothymosin, alpha | -0.0776108 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0733455 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.071811 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0676618 |
| RPL35A | ribosomal protein L35a | -0.0651956 |
| RPLP1 | ribosomal protein, large, P1 | -0.0607742 |
| RPS25 | ribosomal protein S25 | -0.0599374 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0585079 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0555119 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0554524 |
| CST3 | cystatin C | -0.0541591 |
| ANXA2 | annexin A2 | -0.0516905 |
| PKM | pyruvate kinase, muscle | -0.0510561 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0495948 |
| SEC61G | Sec61 gamma subunit | -0.0477642 |
| RPS6 | ribosomal protein S6 | -0.0471371 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0446759 |
| RPS8 | ribosomal protein S8 | -0.0441338 |
| RPL31 | ribosomal protein L31 | -0.0432758 |
| INTS6 | integrator complex subunit 6 | -0.0430538 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0424125 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0423707 |
| RPS24 | ribosomal protein S24 | -0.0419366 |
| KRT7 | keratin 7, type II | -0.0417806 |
| RPL34 | ribosomal protein L34 | -0.0399976 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0395787 |
| S100P | S100 calcium binding protein P | -0.0380054 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0376155 |
| LDHA | lactate dehydrogenase A | -0.0368178 |
| RPLP0 | ribosomal protein, large, P0 | -0.0367233 |
| RPS3 | ribosomal protein S3 | -0.0357379 |
| IER3 | immediate early response 3 | -0.0350836 |
| KRT18 | keratin 18, type I | -0.033856 |
| RPS27A | ribosomal protein S27a | -0.0338276 |
| RPS12 | ribosomal protein S12 | -0.0337717 |
| RPL37A | ribosomal protein L37a | -0.0328608 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0326263 |
| MYOF | myoferlin | -0.0325276 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0322833 |
| HMGA1 | high mobility group AT-hook 1 | -0.0322681 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0316468 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0306998 |
| S100A6 | S100 calcium binding protein A6 | -0.0305717 |
| RPS29 | ribosomal protein S29 | -0.0303319 |
| B2M | beta-2-microglobulin | -0.030105 |
| RPS23 | ribosomal protein S23 | -0.029705 |
| AGR2 | anterior gradient 2 | -0.0295479 |
| HLA-B | major histocompatibility complex, class I, B | -0.0295296 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0294034 |
| GNAS | GNAS complex locus | -0.0293332 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0293246 |
| CUX1 | cut-like homeobox 1 | -0.0289445 |
| RPL12 | ribosomal protein L12 | -0.0279979 |
| RPL37 | ribosomal protein L37 | -0.0276084 |
| RPL11 | ribosomal protein L11 | -0.0272993 |
| CCND1 | cyclin D1 | -0.0272012 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0268578 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0266713 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0265502 |
| S100A11 | S100 calcium binding protein A11 | -0.026544 |
| RPS19 | ribosomal protein S19 | -0.0263533 |
| CAV2 | caveolin 2 | -0.0260622 |
| RPS17 | ribosomal protein S17 | -0.0260326 |
| RPL8 | ribosomal protein L8 | -0.0258622 |
| RPLP2 | ribosomal protein, large, P2 | -0.025401 |
| RPL19 | ribosomal protein L19 | -0.0242949 |
| RPL36A | ribosomal protein L36a | -0.0239906 |
| RPL23 | ribosomal protein L23 | -0.0239592 |
| RNF213 | ring finger protein 213 | -0.0235672 |
| RPS13 | ribosomal protein S13 | -0.0233498 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0229146 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0228959 |
| AREG | amphiregulin | -0.0227718 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0226786 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0225032 |
| S100A9 | S100 calcium binding protein A9 | -0.022467 |
| RPS27 | ribosomal protein S27 | -0.0224448 |
| TPM4 | tropomyosin 4 | -0.0223898 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0220123 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0219679 |
| ENO1 | enolase 1, (alpha) | -0.0219256 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0219003 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0218759 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0217743 |
| RPL30 | ribosomal protein L30 | -0.0217541 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0217254 |
| ANXA1 | annexin A1 | -0.0216643 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0213574 |
| SERF2 | small EDRK-rich factor 2 | -0.021118 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0209475 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0207012 |
| RPS14 | ribosomal protein S14 | -0.0205036 |
