| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sulfatinib perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Sulfatinib_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.175118 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.127068 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.113179 |
| FAM13A | family with sequence similarity 13, member A | 0.101271 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0990178 |
| FNDC3B | fibronectin type III domain containing 3B | 0.089729 |
| GRB10 | growth factor receptor-bound protein 10 | 0.089071 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0769938 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0720997 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0656932 |
| ATP13A3 | ATPase type 13A3 | 0.0642245 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0635545 |
| RUNX2 | runt-related transcription factor 2 | 0.0627462 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0616247 |
| PRELID2 | PRELI domain containing 2 | 0.0606354 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0578219 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0572432 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.057182 |
| ADD3 | adducin 3 (gamma) | 0.0551922 |
| HELZ | helicase with zinc finger | 0.0534681 |
| PCBP2 | poly(rC) binding protein 2 | 0.0489914 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0488546 |
| NAV2 | neuron navigator 2 | 0.0485235 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0463532 |
| SIK3 | SIK family kinase 3 | 0.0458557 |
| MEF2A | myocyte enhancer factor 2A | 0.0454912 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0451546 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0445025 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0434204 |
| YBX1 | Y box binding protein 1 | 0.043036 |
| NGLY1 | N-glycanase 1 | 0.0427464 |
| DOCK5 | dedicator of cytokinesis 5 | 0.042362 |
| FAM20C | family with sequence similarity 20, member C | 0.0407354 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0391679 |
| ZNF292 | zinc finger protein 292 | 0.0380928 |
| RNF145 | ring finger protein 145 | 0.0378155 |
| OGA | O-GlcNAcase | 0.0368254 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0366991 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0366729 |
| ASPH | aspartate beta-hydroxylase | 0.0364753 |
| USP3 | ubiquitin specific peptidase 3 | 0.0356647 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0355423 |
| MYO1B | myosin IB | 0.0350405 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0342582 |
| NBAS | neuroblastoma amplified sequence | 0.0341493 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0340032 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0335204 |
| RIOK3 | RIO kinase 3 | 0.0318338 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0311148 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0310444 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0308285 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0305873 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0304515 |
| QKI | QKI, KH domain containing, RNA binding | 0.0303663 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0296671 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.029615 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0293324 |
| GPC6 | glypican 6 | 0.0291945 |
| RARB | retinoic acid receptor, beta | 0.0291035 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0289246 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | 0.028788 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0287716 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0287137 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0277728 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0276648 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0274433 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0272581 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0271694 |
| INSIG1 | insulin induced gene 1 | 0.0271595 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0271452 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0270279 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0270214 |
| PTK2 | protein tyrosine kinase 2 | 0.0265709 |
| MYOF | myoferlin | 0.0265141 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0264131 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0260231 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0257395 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0253901 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0252535 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0250391 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0250288 |
| RUNX1 | runt-related transcription factor 1 | 0.02488 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0247632 |
| PDGFC | platelet derived growth factor C | 0.0245572 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0243588 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0243485 |
| AHR | aryl hydrocarbon receptor | 0.0238484 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0232553 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0232257 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.023199 |
| SLTM | SAFB-like, transcription modulator | 0.022993 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0228989 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0227778 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0227384 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0226664 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0225354 |
| LOXL2 | lysyl oxidase-like 2 | 0.0223828 |
| SDC4 | syndecan 4 | 0.0222499 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0222094 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0220616 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.193242 |
| VIM | vimentin | -0.117157 |
| MT2A | metallothionein 2A | -0.107418 |
| CD44 | CD44 molecule (Indian blood group) | -0.0888768 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0868248 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0753263 |
| NDRG1 | N-myc downstream regulated 1 | -0.0751778 |
| STC1 | stanniocalcin 1 | -0.074158 |
| TMSB10 | thymosin beta 10 | -0.0724735 |
| LOX | lysyl oxidase | -0.0681913 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0607422 |
| USP34 | ubiquitin specific peptidase 34 | -0.0548889 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0531388 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0453751 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0447378 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0433198 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.043178 |
| EGFR | epidermal growth factor receptor | -0.0424796 |
| BPTF | bromodomain PHD finger transcription factor | -0.0423452 |
| RPLP1 | ribosomal protein, large, P1 | -0.0420318 |
| GLCCI1 | glucocorticoid induced 1 | -0.0417066 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0416275 |
| NTN4 | netrin 4 | -0.0387382 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0366513 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.036428 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.035715 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0354255 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0348892 |
| RPS19 | ribosomal protein S19 | -0.0348127 |
| SYT1 | synaptotagmin I | -0.033442 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0323888 |
| S100A10 | S100 calcium binding protein A10 | -0.0321126 |
| TMSB4X | thymosin beta 4, X-linked | -0.0321052 |
| EXT1 | exostosin glycosyltransferase 1 | -0.031924 |
| RPS2 | ribosomal protein S2 | -0.0318921 |
| EHBP1 | EH domain binding protein 1 | -0.0318908 |
| HDLBP | high density lipoprotein binding protein | -0.0315314 |
| CDCP1 | CUB domain containing protein 1 | -0.0311142 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0306957 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0305786 |
| ECE1 | endothelin converting enzyme 1 | -0.0302756 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0301748 |
| BMERB1 | bMERB domain containing 1 | -0.029904 |
| RNF24 | ring finger protein 24 | -0.0296825 |
| RPL38 | ribosomal protein L38 | -0.0295934 |
| FNBP1 | formin binding protein 1 | -0.0291065 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0288711 |
| RSU1 | Ras suppressor protein 1 | -0.0286339 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0273692 |
| CEP350 | centrosomal protein 350kDa | -0.0271636 |
| MYO10 | myosin X | -0.0271531 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0271193 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0271138 |
| RPS13 | ribosomal protein S13 | -0.0270886 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0270349 |
| FN1 | fibronectin 1 | -0.0268452 |
| SEPTIN9 | septin 9 | -0.0259929 |
| S100A6 | S100 calcium binding protein A6 | -0.0257987 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.025239 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0251813 |
| MYO9A | myosin IXA | -0.024927 |
| FRMD4A | FERM domain containing 4A | -0.0248995 |
| ATF7 | activating transcription factor 7 | -0.0245197 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0245191 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0243229 |
| NRP1 | neuropilin 1 | -0.0242005 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0241263 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0239991 |
| RPL32 | ribosomal protein L32 | -0.0238949 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0235997 |
| RPL31 | ribosomal protein L31 | -0.0234297 |
| DUSP5 | dual specificity phosphatase 5 | -0.0227113 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0225741 |
| RPL35A | ribosomal protein L35a | -0.0223179 |
| HLA-B | major histocompatibility complex, class I, B | -0.0222626 |
| HMGA1 | high mobility group AT-hook 1 | -0.0222586 |
| GLG1 | golgi glycoprotein 1 | -0.021929 |
| RPLP2 | ribosomal protein, large, P2 | -0.0218495 |
| SNX6 | sorting nexin 6 | -0.0217417 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0217377 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0216925 |
| KSR1 | kinase suppressor of ras 1 | -0.0214935 |
| HM13 | histocompatibility (minor) 13 | -0.0214442 |
| CLTC | clathrin, heavy chain (Hc) | -0.0213334 |
| FTL | ferritin, light polypeptide | -0.0211117 |
| RPS21 | ribosomal protein S21 | -0.0209218 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0208913 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.0208069 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.020797 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0207855 |
| RPL28 | ribosomal protein L28 | -0.0207568 |
| RPL12 | ribosomal protein L12 | -0.0207427 |
| SLFN5 | schlafen family member 5 | -0.0206757 |
| PRKCA | protein kinase C, alpha | -0.0206726 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | -0.0206027 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | -0.020556 |
| RPS24 | ribosomal protein S24 | -0.020521 |
| NUMB | numb homolog (Drosophila) | -0.0204226 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0203865 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0203677 |
