| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sulfatinib perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Sulfatinib_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.300668 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.141142 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.122708 |
| ASPH | aspartate beta-hydroxylase | 0.11847 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0886981 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0691204 |
| TXNRD1 | thioredoxin reductase 1 | 0.0676279 |
| YBX1 | Y box binding protein 1 | 0.0644953 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0611391 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.054784 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0519994 |
| ENO1 | enolase 1, (alpha) | 0.0515591 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0481161 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0480325 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.043346 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0413176 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0351206 |
| KYNU | kynureninase | 0.0351078 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0349707 |
| AHNAK | AHNAK nucleoprotein | 0.0338244 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0329997 |
| CANX | calnexin | 0.0326441 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0319389 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0316439 |
| THBS1 | thrombospondin 1 | 0.0310328 |
| FGB | fibrinogen beta chain | 0.0304405 |
| LDHA | lactate dehydrogenase A | 0.030071 |
| RPL4 | ribosomal protein L4 | 0.0294864 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0294705 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0288596 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0280911 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0280132 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0279432 |
| TPM4 | tropomyosin 4 | 0.0277652 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0273764 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0272795 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0267069 |
| SDC4 | syndecan 4 | 0.0266349 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.026469 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0262071 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0259393 |
| MYOF | myoferlin | 0.0257857 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | 0.0256072 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0246987 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0244576 |
| ANXA2 | annexin A2 | 0.0242983 |
| TPM3 | tropomyosin 3 | 0.0237993 |
| BICC1 | BicC family RNA binding protein 1 | 0.0236219 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0236062 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | 0.0233612 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0232728 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0232404 |
| IL6 | interleukin 6 | 0.0228798 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0227594 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0220945 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0219691 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.021298 |
| ZNF804A | zinc finger protein 804A | 0.0212655 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.021193 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0210574 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0209435 |
| CLU | clusterin | 0.0209148 |
| FGG | fibrinogen gamma chain | 0.020906 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0208901 |
| TAGLN2 | transgelin 2 | 0.020178 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0201372 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.0200924 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0200206 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0199792 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0198575 |
| AHR | aryl hydrocarbon receptor | 0.0197737 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0197306 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0195863 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | 0.0194006 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0193051 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0192325 |
| FAM168A | family with sequence similarity 168, member A | 0.019225 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0191374 |
| ECT2 | epithelial cell transforming 2 | 0.0188485 |
| EFNA5 | ephrin-A5 | 0.0185941 |
| FHIT | fragile histidine triad | 0.0185517 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.017968 |
| VDAC1 | voltage-dependent anion channel 1 | 0.0179072 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0178336 |
| UTRN | utrophin | 0.0178165 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.0177921 |
| TMED10 | transmembrane emp24-like trafficking protein 10 (yeast) | 0.0177334 |
| FGA | fibrinogen alpha chain | 0.0173268 |
| SKP1 | S-phase kinase-associated protein 1 | 0.017254 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.0172485 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0172329 |
| RRM2 | ribonucleotide reductase M2 | 0.0171484 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0168682 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0168384 |
| ETV3 | ets variant 3 | 0.0167344 |
| CD109 | CD109 molecule | 0.016693 |
| SRGN | serglycin | 0.0165443 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0164771 |
| CALR | calreticulin | 0.0164078 |
| MOK | MOK protein kinase | 0.0163257 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.431596 |
| GRAMD1B | GRAM domain containing 1B | -0.13451 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0838188 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0797002 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0786666 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0752463 |
| RPS2 | ribosomal protein S2 | -0.074808 |
| IER3 | immediate early response 3 | -0.0666013 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0663427 |
| PFDN2 | prefoldin subunit 2 | -0.0591826 |
| RTN4 | reticulon 4 | -0.0552406 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.0540089 |
| RBM39 | RNA binding motif protein 39 | -0.0535364 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0527221 |
| ACTG1 | actin gamma 1 | -0.0527058 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0504149 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0491755 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0476789 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.04736 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0468853 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0463962 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0458126 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.04442 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0442636 |
| STC1 | stanniocalcin 1 | -0.0442088 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0417287 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0415868 |
| RPL23 | ribosomal protein L23 | -0.0401036 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0388721 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0388691 |
| TMSB10 | thymosin beta 10 | -0.0375014 |
| KIF5B | kinesin family member 5B | -0.0368532 |
| USP34 | ubiquitin specific peptidase 34 | -0.0354017 |
| RPS12 | ribosomal protein S12 | -0.03413 |
| ZNF207 | zinc finger protein 207 | -0.0337812 |
| RPL7 | ribosomal protein L7 | -0.0331061 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0327722 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0327615 |
| GLG1 | golgi glycoprotein 1 | -0.0327479 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0327015 |
| BMP6 | bone morphogenetic protein 6 | -0.0326722 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0320954 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0318842 |
| SVIL | supervillin | -0.0314215 |
| RHEB | Ras homolog enriched in brain | -0.0310777 |
| RPS25 | ribosomal protein S25 | -0.0308754 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0303135 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0299052 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0297549 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0293814 |
| PARD3 | par-3 family cell polarity regulator | -0.0291389 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0289565 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0288939 |
| BRD2 | bromodomain containing 2 | -0.0288508 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0286377 |
| RPL19 | ribosomal protein L19 | -0.0285979 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0280855 |
| FAM13B | family with sequence similarity 13, member B | -0.0278102 |
| WWOX | WW domain containing oxidoreductase | -0.0274833 |
| FAM168B | family with sequence similarity 168, member B | -0.0273843 |
| SRPK1 | SRSF protein kinase 1 | -0.0272831 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0271517 |
| S100A6 | S100 calcium binding protein A6 | -0.0267128 |
| CCNY | cyclin Y | -0.0266268 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0264057 |
| NPLOC4 | nuclear protein localization 4 homolog (S. cerevisiae) | -0.0263705 |
| NCOA1 | nuclear receptor coactivator 1 | -0.0263566 |
| ATXN1 | ataxin 1 | -0.0262575 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0261241 |
| EXOC6B | exocyst complex component 6B | -0.0260824 |
| NUMB | numb homolog (Drosophila) | -0.0259743 |
| GOLT1B | golgi transport 1B | -0.0259353 |
| MRTFA | myocardin related transcription factor A | -0.0258267 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.025722 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0253629 |
| MEMO1 | mediator of cell motility 1 | -0.0252424 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0252314 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0251789 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0251725 |
| RPL38 | ribosomal protein L38 | -0.0251699 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0250304 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0248682 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.024715 |
| ATAD2B | ATPase family, AAA domain containing 2B | -0.024434 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0244067 |
| UPP1 | uridine phosphorylase 1 | -0.0243998 |
| TERF2IP | telomeric repeat binding factor 2, interacting protein | -0.0243388 |
| SPAG9 | sperm associated antigen 9 | -0.0239475 |
| CYRIB | CYFIP related Rac1 interactor B | -0.0239463 |
| GPHN | gephyrin | -0.0237612 |
| RSRP1 | arginine/serine-rich protein 1 | -0.0237335 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0236565 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.0236451 |
| RAB10 | RAB10, member RAS oncogene family | -0.0234363 |
| RPL36A | ribosomal protein L36a | -0.0233917 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0233209 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0231847 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | -0.023073 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0229745 |
| MATR3 | matrin 3 | -0.0229572 |
