| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sulfatinib perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Sulfatinib_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.167193 |
| LAMB3 | laminin, beta 3 | 0.103025 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.102724 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.078793 |
| KYNU | kynureninase | 0.0719512 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0687613 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0680999 |
| UBC | ubiquitin C | 0.0602553 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0599812 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0597428 |
| KRT17 | keratin 17, type I | 0.0593937 |
| ASPH | aspartate beta-hydroxylase | 0.0571356 |
| SDC4 | syndecan 4 | 0.0557039 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0549278 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0540683 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.053795 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0523533 |
| MCL1 | myeloid cell leukemia 1 | 0.0522784 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0517759 |
| EZR | ezrin | 0.0497123 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.049437 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0493665 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0485913 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0475919 |
| CD109 | CD109 molecule | 0.0475651 |
| FMNL2 | formin-like 2 | 0.0475537 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0470671 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0465367 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0464548 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.046315 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0460156 |
| USP3 | ubiquitin specific peptidase 3 | 0.0458912 |
| RBM39 | RNA binding motif protein 39 | 0.0455374 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.045292 |
| FRY | furry homolog (Drosophila) | 0.0450429 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0449471 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0447133 |
| MYO1E | myosin IE | 0.0446657 |
| HELZ | helicase with zinc finger | 0.0446448 |
| ERBIN | erbb2 interacting protein | 0.0444021 |
| S100A9 | S100 calcium binding protein A9 | 0.0440456 |
| TXNRD1 | thioredoxin reductase 1 | 0.0440408 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0440358 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.043848 |
| MYOF | myoferlin | 0.042426 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0424057 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0422979 |
| STC1 | stanniocalcin 1 | 0.0415667 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0411705 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0411665 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0411104 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0406213 |
| NABP1 | nucleic acid binding protein 1 | 0.0391116 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0390785 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0386827 |
| RRM2 | ribonucleotide reductase M2 | 0.0385329 |
| FLNB | filamin B, beta | 0.0378321 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0373498 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0372502 |
| TPR | translocated promoter region, nuclear basket protein | 0.0367475 |
| ANXA2 | annexin A2 | 0.0360082 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0359739 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0355758 |
| SMAD3 | SMAD family member 3 | 0.0352599 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0352176 |
| CANX | calnexin | 0.0350757 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0345831 |
| FOXO3 | forkhead box O3 | 0.0345132 |
| USP53 | ubiquitin specific peptidase 53 | 0.0344767 |
| MATR3 | matrin 3 | 0.0344316 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0340374 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0338987 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0332409 |
| TC2N | tandem C2 domains, nuclear | 0.0330889 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0329019 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0324071 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.031798 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0317907 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0315906 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0312949 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0310797 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0308088 |
| SBF2 | SET binding factor 2 | 0.0305987 |
| MXD1 | MAX dimerization protein 1 | 0.0304088 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0302784 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0300031 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0299865 |
| COG5 | component of oligomeric golgi complex 5 | 0.0297885 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0297865 |
| RNF24 | ring finger protein 24 | 0.0297765 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0292443 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0288349 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.028707 |
| FMN1 | formin 1 | 0.0284782 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0281672 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0278958 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0277751 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0276781 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0274874 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.027018 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.119196 |
| PTMA | prothymosin, alpha | -0.117584 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0904605 |
| HLA-B | major histocompatibility complex, class I, B | -0.0695336 |
| RPS6 | ribosomal protein S6 | -0.0656708 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0641598 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0636485 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0618976 |
| RPLP1 | ribosomal protein, large, P1 | -0.0607827 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0573238 |
| AK1 | adenylate kinase 1 | -0.0540262 |
| IGF2 | insulin-like growth factor 2 | -0.0520884 |
| NUP98 | nucleoporin 98kDa | -0.0497118 |
| MED13L | mediator complex subunit 13-like | -0.0489653 |
| RPS8 | ribosomal protein S8 | -0.0479933 |
| RPLP2 | ribosomal protein, large, P2 | -0.0462844 |
| NSRP1 | nuclear speckle splicing regulatory protein 1 | -0.0455709 |
| PGK1 | phosphoglycerate kinase 1 | -0.0438084 |
| FAT1 | FAT atypical cadherin 1 | -0.0434763 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0434745 |
| TMSB10 | thymosin beta 10 | -0.0428492 |
| RPS11 | ribosomal protein S11 | -0.0426467 |
| ZNF638 | zinc finger protein 638 | -0.0418319 |
| RBM25 | RNA binding motif protein 25 | -0.0410721 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0410543 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0403432 |
| CNKSR3 | CNKSR family member 3 | -0.0393688 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0389974 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0385471 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0380038 |
| GOLGA2 | golgin A2 | -0.0376014 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0374546 |
| DENND1A | DENN/MADD domain containing 1A | -0.0373727 |
| RPL15 | ribosomal protein L15 | -0.0366666 |
| CALR | calreticulin | -0.0366086 |
| SMYD3 | SET and MYND domain containing 3 | -0.0365592 |
| RPL19 | ribosomal protein L19 | -0.036012 |
| SEPTIN7 | septin 7 | -0.0358631 |
| RPS19 | ribosomal protein S19 | -0.0355631 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.0354701 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0352 |
| B2M | beta-2-microglobulin | -0.0351316 |
| RPS21 | ribosomal protein S21 | -0.0348601 |
| H1-0 | H1.0 linker histone | -0.0347872 |
| RPS27A | ribosomal protein S27a | -0.0347344 |
| RPS12 | ribosomal protein S12 | -0.0345435 |
| RPL11 | ribosomal protein L11 | -0.0341899 |
| RPS25 | ribosomal protein S25 | -0.034183 |
| RPL35A | ribosomal protein L35a | -0.0338723 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0336789 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0336327 |
| SRPK2 | SRSF protein kinase 2 | -0.0332993 |
| AGO3 | argonaute RISC catalytic component 3 | -0.0331306 |
| HMGB1 | high mobility group box 1 | -0.0330097 |
| ZNF292 | zinc finger protein 292 | -0.0329339 |
| RPL7 | ribosomal protein L7 | -0.0324605 |
| MSI2 | musashi RNA-binding protein 2 | -0.0323126 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0322901 |
| GOLGB1 | golgin B1 | -0.0318142 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0317286 |
| PDE10A | phosphodiesterase 10A | -0.0315788 |
| EGFR | epidermal growth factor receptor | -0.0315574 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0310261 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0301779 |
| TMEM263 | transmembrane protein 263 | -0.029985 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | -0.0298896 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0297445 |
| USP33 | ubiquitin specific peptidase 33 | -0.029717 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.029714 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0294333 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0293511 |
| NCKAP1 | NCK-associated protein 1 | -0.0293494 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.029333 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0293304 |
| MAP7 | microtubule-associated protein 7 | -0.0292287 |
| RPS17 | ribosomal protein S17 | -0.0290068 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0289879 |
| SLC38A2 | solute carrier family 38, member 2 | -0.028751 |
| RPL9 | ribosomal protein L9 | -0.028528 |
| RPL8 | ribosomal protein L8 | -0.0282057 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.028105 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.027867 |
| INSIG1 | insulin induced gene 1 | -0.0277308 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0277017 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | -0.0270973 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | -0.0270367 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0269704 |
| RPS13 | ribosomal protein S13 | -0.0269699 |
| RPL31 | ribosomal protein L31 | -0.026688 |
| MAP1B | microtubule-associated protein 1B | -0.0260896 |
| NAV2 | neuron navigator 2 | -0.0258164 |
| RLF | rearranged L-myc fusion | -0.0257789 |
| NRG1 | neuregulin 1 | -0.025609 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0256087 |
| RPL38 | ribosomal protein L38 | -0.0251602 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0251458 |
| STAU2 | staufen double-stranded RNA binding protein 2 | -0.0251312 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0249379 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0248936 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0244035 |
