| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sulfatinib perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sulfatinib_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | 0.152231 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.115854 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.109625 |
| EFNA5 | ephrin-A5 | 0.0993977 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0808877 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0773053 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0759858 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0659102 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0647447 |
| DST | dystonin | 0.064114 |
| NRCAM | neuronal cell adhesion molecule | 0.0619715 |
| PCBP3 | poly(rC) binding protein 3 | 0.0589529 |
| NEK7 | NIMA-related kinase 7 | 0.0573432 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0531001 |
| KYNU | kynureninase | 0.0529356 |
| CTSC | cathepsin C | 0.052278 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0463121 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0450439 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0444121 |
| COL5A2 | collagen, type V, alpha 2 | 0.0434877 |
| GDA | guanine deaminase | 0.0432346 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0410491 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0399734 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0376672 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0328729 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.0318349 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0309752 |
| COL4A6 | collagen, type IV, alpha 6 | 0.0297106 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0277473 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0270066 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0267519 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0259612 |
| MSN | moesin | 0.0259232 |
| PDE10A | phosphodiesterase 10A | 0.0258642 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0254776 |
| NBAS | neuroblastoma amplified sequence | 0.0251875 |
| CDH13 | cadherin 13 | 0.0250646 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0249085 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0246256 |
| GPRIN3 | GPRIN family member 3 | 0.0244226 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0242949 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0239545 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.023896 |
| RTN4 | reticulon 4 | 0.0237812 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0237609 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0233602 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0232779 |
| RBM39 | RNA binding motif protein 39 | 0.0227511 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0225554 |
| CD109 | CD109 molecule | 0.0225444 |
| NCKAP1 | NCK-associated protein 1 | 0.022431 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0222611 |
| ZNF292 | zinc finger protein 292 | 0.0219749 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0217883 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0213537 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0210572 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0207471 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0202395 |
| WDR43 | WD repeat domain 43 | 0.0200127 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0199642 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.019778 |
| OGA | O-GlcNAcase | 0.0197185 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0197086 |
| RNF145 | ring finger protein 145 | 0.0196493 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0196118 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0194612 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0193988 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0191326 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0191108 |
| SUCO | SUN domain containing ossification factor | 0.0189555 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0187018 |
| TNPO1 | transportin 1 | 0.0186303 |
| HELZ | helicase with zinc finger | 0.0185389 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0183655 |
| CUL3 | cullin 3 | 0.0183612 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0181908 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | 0.018166 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0181193 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0180069 |
| MALT1 | MALT1 paracaspase | 0.0179111 |
| TXNRD1 | thioredoxin reductase 1 | 0.0177931 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0177773 |
| CLTC | clathrin, heavy chain (Hc) | 0.0176303 |
| UBQLN1 | ubiquilin 1 | 0.0175043 |
| GPC6 | glypican 6 | 0.0174584 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0174166 |
| NHSL1 | NHS-like 1 | 0.0173046 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0172935 |
| SP3 | Sp3 transcription factor | 0.0170302 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0168673 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0167612 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0167539 |
| FAM13A | family with sequence similarity 13, member A | 0.0166361 |
| ECT2 | epithelial cell transforming 2 | 0.016519 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0164936 |
| H1-4 | H1.4 linker histone, cluster member | 0.0163574 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0159601 |
| ENAH | enabled homolog (Drosophila) | 0.015877 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0158678 |
| BDNF | brain-derived neurotrophic factor | 0.0158354 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.281544 |
| FN1 | fibronectin 1 | -0.186233 |
| VIM | vimentin | -0.174735 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.158211 |
| TMSB10 | thymosin beta 10 | -0.14958 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.134819 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0780946 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0766597 |
| RPLP1 | ribosomal protein, large, P1 | -0.0737218 |
| PTMA | prothymosin, alpha | -0.0734718 |
| FTL | ferritin, light polypeptide | -0.072749 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0696866 |
| RPS27A | ribosomal protein S27a | -0.065928 |
| S100A6 | S100 calcium binding protein A6 | -0.0655495 |
| RPL12 | ribosomal protein L12 | -0.0626616 |
| RPS6 | ribosomal protein S6 | -0.0626142 |
| RPL23 | ribosomal protein L23 | -0.0603921 |
| RPS24 | ribosomal protein S24 | -0.0581368 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0564247 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.056286 |
| RPS8 | ribosomal protein S8 | -0.05262 |
| RPL31 | ribosomal protein L31 | -0.0524417 |
| S100A10 | S100 calcium binding protein A10 | -0.0516311 |
| UBC | ubiquitin C | -0.0503824 |
| MT2A | metallothionein 2A | -0.0493335 |
| RPS23 | ribosomal protein S23 | -0.0468463 |
| RPLP0 | ribosomal protein, large, P0 | -0.0465971 |
| ACTG1 | actin gamma 1 | -0.0446284 |
| RPS4X | ribosomal protein S4, X-linked | -0.0443828 |
| RPL19 | ribosomal protein L19 | -0.0438172 |
| RPL36A | ribosomal protein L36a | -0.0433888 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0432285 |
| RPS19 | ribosomal protein S19 | -0.0432209 |
| RPL37A | ribosomal protein L37a | -0.0430725 |
| RPL35A | ribosomal protein L35a | -0.0425806 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0422924 |
| RPL26 | ribosomal protein L26 | -0.0413999 |
| RPS12 | ribosomal protein S12 | -0.0403083 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0394868 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0390408 |
| B2M | beta-2-microglobulin | -0.0386869 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.03823 |
| GNAS | GNAS complex locus | -0.037077 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.03669 |
| RACK1 | receptor for activated C kinase 1 | -0.0365654 |
| NDRG1 | N-myc downstream regulated 1 | -0.0363272 |
| RPS3 | ribosomal protein S3 | -0.0362613 |
| SRGN | serglycin | -0.0357751 |
| RPL7A | ribosomal protein L7a | -0.0356316 |
| RPL34 | ribosomal protein L34 | -0.0355673 |
| RPS27 | ribosomal protein S27 | -0.0351957 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0343254 |
| STC1 | stanniocalcin 1 | -0.0343098 |
| RPS25 | ribosomal protein S25 | -0.0339134 |
| RPS16 | ribosomal protein S16 | -0.0336451 |
| RPLP2 | ribosomal protein, large, P2 | -0.0334363 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0334292 |
| RPL9 | ribosomal protein L9 | -0.0330273 |
| CANX | calnexin | -0.0329986 |
| RPS14 | ribosomal protein S14 | -0.0329177 |
| RPS13 | ribosomal protein S13 | -0.0328002 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0323778 |
| HLA-B | major histocompatibility complex, class I, B | -0.0319 |
| RPL36 | ribosomal protein L36 | -0.0318666 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0311027 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.030046 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0296816 |
| HLA-A | major histocompatibility complex, class I, A | -0.0288701 |
| PKM | pyruvate kinase, muscle | -0.0285734 |
| RPS29 | ribosomal protein S29 | -0.0280796 |
| LDHA | lactate dehydrogenase A | -0.0280533 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0280094 |
| ASTN2 | astrotactin 2 | -0.0279373 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.027747 |
| RPL38 | ribosomal protein L38 | -0.0276971 |
| RPL37 | ribosomal protein L37 | -0.0276247 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0268073 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0267936 |
| TPI1 | triosephosphate isomerase 1 | -0.0265891 |
| MAP7 | microtubule-associated protein 7 | -0.0259696 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0258711 |
| RPS21 | ribosomal protein S21 | -0.0251293 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0249135 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0245397 |
| RPS5 | ribosomal protein S5 | -0.0241205 |
| RPL35 | ribosomal protein L35 | -0.0240817 |
| CUX1 | cut-like homeobox 1 | -0.023924 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0237596 |
| SMYD3 | SET and MYND domain containing 3 | -0.023745 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0237298 |
| RPL5 | ribosomal protein L5 | -0.0236701 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0236034 |
| RPL32 | ribosomal protein L32 | -0.0235578 |
| RPL28 | ribosomal protein L28 | -0.023437 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0232418 |
| ENO1 | enolase 1, (alpha) | -0.0231651 |
| CALR | calreticulin | -0.0229681 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0229442 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0221816 |
| PCBP2 | poly(rC) binding protein 2 | -0.0220997 |
