Sulfatinib_SNU-1 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Sulfatinib perturbation in SNU-1 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Sulfatinib_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
PDE4B phosphodiesterase 4B, cAMP-specific 0.144185
VCL vinculin 0.135491
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.134795
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 0.13043
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 0.123785
CPED1 cadherin-like and PC-esterase domain containing 1 0.121007
PDGFC platelet derived growth factor C 0.11829
ENOX1 ecto-NOX disulfide-thiol exchanger 1 0.107424
AHNAK AHNAK nucleoprotein 0.102226
LPP LIM domain containing preferred translocation partner in lipoma 0.0952549
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.0880756
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.082545
RBMS3 RNA binding motif, single stranded interacting protein 3 0.0820766
ZEB1 zinc finger E-box binding homeobox 1 0.0789882
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0760641
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.0737806
SSBP2 single-stranded DNA binding protein 2 0.072883
NBEA neurobeachin 0.0669245
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0667672
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.0661955
EVI5 ecotropic viral integration site 5 0.065424
SAMD4A sterile alpha motif domain containing 4A 0.0650915
ECT2 epithelial cell transforming 2 0.0647671
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0646703
SOX6 SRY (sex determining region Y)-box 6 0.0636638
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0634247
GOLGA4 golgin A4 0.0625696
PICALM phosphatidylinositol binding clathrin assembly protein 0.0624135
FLNB filamin B, beta 0.0608341
DSCAM Down syndrome cell adhesion molecule 0.0581315
DLG1 discs, large homolog 1 (Drosophila) 0.0573797
CD47 CD47 molecule 0.0572195
EFNA5 ephrin-A5 0.0557273
PLXNA1 plexin A1 0.0541054
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.0533488
PRELID2 PRELI domain containing 2 0.053105
PARD3 par-3 family cell polarity regulator 0.0520619
PUM2 pumilio RNA-binding family member 2 0.0508341
HDLBP high density lipoprotein binding protein 0.0507147
CNOT6L CCR4-NOT transcription complex, subunit 6-like 0.0501608
TGFBR3 transforming growth factor, beta receptor III 0.0500137
TMSB4X thymosin beta 4, X-linked 0.0491282
ZNF292 zinc finger protein 292 0.0485478
CACNB4 calcium channel, voltage-dependent, beta 4 subunit 0.0480974
PTK2 protein tyrosine kinase 2 0.047707
RTN4 reticulon 4 0.0469077
RBM39 RNA binding motif protein 39 0.0467128
GNPDA1 glucosamine-6-phosphate deaminase 1 0.046296
ELOVL5 ELOVL fatty acid elongase 5 0.0460268
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 0.0455183
TJP1 tight junction protein 1 0.0454772
NFIA nuclear factor I/A 0.0448422
SBF2 SET binding factor 2 0.0441615
CCNL1 cyclin L1 0.0436005
TTC3 tetratricopeptide repeat domain 3 0.0432349
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 0.0426335
CDC73 cell division cycle 73 0.0424117
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0420963
NBAS neuroblastoma amplified sequence 0.0414058
PGK1 phosphoglycerate kinase 1 0.0412571
TXNIP thioredoxin interacting protein 0.0408739
HDAC9 histone deacetylase 9 0.0403502
CALR calreticulin 0.0399745
ADAM10 ADAM metallopeptidase domain 10 0.0399567
EPS8 epidermal growth factor receptor pathway substrate 8 0.0399487
WDR43 WD repeat domain 43 0.0397112
RBM25 RNA binding motif protein 25 0.0397101
PTBP2 polypyrimidine tract binding protein 2 0.0395662
PYGB phosphorylase, glycogen; brain 0.0389953
QKI QKI, KH domain containing, RNA binding 0.0388677
KDM3A lysine (K)-specific demethylase 3A 0.0386584
ZFC3H1 zinc finger, C3H1-type containing 0.0385898
FOXP1 forkhead box P1 0.0379368
RPL4 ribosomal protein L4 0.0371245
LOXL3 lysyl oxidase-like 3 0.0367223
PNISR PNN-interacting serine/arginine-rich protein 0.0364135
JMJD1C jumonji domain containing 1C 0.0362192
SET SET nuclear proto-oncogene 0.0361944
SRRM2 serine/arginine repetitive matrix 2 0.0359182
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0358665
CNOT1 CCR4-NOT transcription complex, subunit 1 0.0353663
CAMKMT calmodulin-lysine N-methyltransferase 0.0353577
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like 0.0349783
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.0332949
PPP1R9A protein phosphatase 1, regulatory subunit 9A 0.0330146
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 0.0329085
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.0327585
AHI1 Abelson helper integration site 1 0.0323593
RPL13A ribosomal protein L13a 0.0323243
TMEM263 transmembrane protein 263 0.0315999
ASXL1 additional sex combs like transcriptional regulator 1 0.031471
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0312658
YBX1 Y box binding protein 1 0.0311855
NT5C2 5'-nucleotidase, cytosolic II 0.0310481
TRA2A transformer 2 alpha homolog (Drosophila) 0.0310016
DPYD dihydropyrimidine dehydrogenase 0.0304459
EIF4B eukaryotic translation initiation factor 4B 0.0304391
OGA O-GlcNAcase 0.0302343
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.0301064
COG5 component of oligomeric golgi complex 5 0.0300617

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.206311
TPT1 tumor protein, translationally-controlled 1 -0.0906913
CCND1 cyclin D1 -0.0818367
BMP10 bone morphogenetic protein 10 -0.0758212
PKM pyruvate kinase, muscle -0.0679584
RPS2 ribosomal protein S2 -0.05649
MKI67 marker of proliferation Ki-67 -0.0529558
ARL4C ADP-ribosylation factor-like 4C -0.0509946
RPS6 ribosomal protein S6 -0.049335
RPLP1 ribosomal protein, large, P1 -0.0479023
CENPF centromere protein F, 350/400kDa -0.0475324
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) -0.0451878
ACTG1 actin gamma 1 -0.0448362
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0437709
S100A10 S100 calcium binding protein A10 -0.0428451
RPL35A ribosomal protein L35a -0.0394505
RPL7A ribosomal protein L7a -0.037933
LOC102724023 ES1 protein homolog, mitochondrial -0.037014
RPS8 ribosomal protein S8 -0.0355358
HJURP Holliday junction recognition protein -0.0354584
RPL26 ribosomal protein L26 -0.0352903
RPS13 ribosomal protein S13 -0.0351909
RPL31 ribosomal protein L31 -0.0338192
IRF2BP2 interferon regulatory factor 2 binding protein 2 -0.0330817
RPL38 ribosomal protein L38 -0.0328877
IFI16 interferon, gamma-inducible protein 16 -0.0312003
RPL36 ribosomal protein L36 -0.0302051
RPS25 ribosomal protein S25 -0.0298115
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -0.0295028
ERC2 ELKS/RAB6-interacting/CAST family member 2 -0.029367
USP34 ubiquitin specific peptidase 34 -0.0287849
TASOR2 transcription activation suppressor family member 2 -0.0286678
FTL ferritin, light polypeptide -0.0286473
RPS5 ribosomal protein S5 -0.028324
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -0.0283174
DUSP6 dual specificity phosphatase 6 -0.0282039
SMC4 structural maintenance of chromosomes 4 -0.0281767
NIPBL Nipped-B homolog (Drosophila) -0.0280927
TUBB4B tubulin, beta 4B class IVb -0.0278366
RPL36A ribosomal protein L36a -0.0275395
RPL9 ribosomal protein L9 -0.0275047
PDE4D phosphodiesterase 4D, cAMP-specific -0.026147
MT2A metallothionein 2A -0.0251141
POTEF POTE ankyrin domain family, member F -0.0247497
UBC ubiquitin C -0.024613
RPL27A ribosomal protein L27a -0.0244191
RPLP2 ribosomal protein, large, P2 -0.0241094
S100A6 S100 calcium binding protein A6 -0.0239763
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) -0.0237685
NAV2 neuron navigator 2 -0.0237411
S100A11 S100 calcium binding protein A11 -0.023522
B2M beta-2-microglobulin -0.0234954
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0234707
SPRY4 sprouty homolog 4 (Drosophila) -0.0234187
TUBA1B tubulin, alpha 1b -0.0230986
RPS12 ribosomal protein S12 -0.0226919
RPL12 ribosomal protein L12 -0.0226584
RPS23 ribosomal protein S23 -0.0226111
RPL17-C18ORF32 RPL17-C18orf32 readthrough -0.0225807
FAM162A family with sequence similarity 162, member A -0.0225623
MACROD2 MACRO domain containing 2 -0.0224924
RPL7 ribosomal protein L7 -0.0224345
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.0223152
TAOK1 TAO kinase 1 -0.021165
RPS10 ribosomal protein S10 -0.0210952
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa -0.0209353
RPS24 ribosomal protein S24 -0.0208499
RPS16 ribosomal protein S16 -0.0208463
SCLT1 sodium channel and clathrin linker 1 -0.0208463
FN1 fibronectin 1 -0.0204634
ASTN2 astrotactin 2 -0.0202803
S100A9 S100 calcium binding protein A9 -0.0200739
NFE2L2 nuclear factor, erythroid 2-like 2 -0.0200272
HMGA1 high mobility group AT-hook 1 -0.0200123
RPL34 ribosomal protein L34 -0.0197337
HSPB1 heat shock 27kDa protein 1 -0.0197092
RBM3 RNA binding motif (RNP1, RRM) protein 3 -0.019661
RRM2 ribonucleotide reductase M2 -0.0195107
VDAC1 voltage-dependent anion channel 1 -0.0194955
CENPE centromere protein E, 312kDa -0.0194513
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0192534
RPS27 ribosomal protein S27 -0.0192246
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 -0.0191944
KIF18B kinesin family member 18B -0.0191137
CALM1 calmodulin 1 (phosphorylase kinase, delta) -0.0189208
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa -0.0187695
CREBBP CREB binding protein -0.0185773
RPS15 ribosomal protein S15 -0.0185456
RPS17 ribosomal protein S17 -0.0183514
RPL37 ribosomal protein L37 -0.0183386
HSPA8 heat shock 70kDa protein 8 -0.0182438
RPL21 ribosomal protein L21 -0.0181724
PFN1 profilin 1 -0.0180672
ZBTB10 zinc finger and BTB domain containing 10 -0.0177443
DEK DEK proto-oncogene -0.0177073
VTI1A vesicle transport through interaction with t-SNAREs 1A -0.0176528
RPL8 ribosomal protein L8 -0.0175082
DARS1 aspartyl-tRNA synthetase 1 -0.0174178
CCNI cyclin I -0.0173446
RPL27 ribosomal protein L27 -0.0168558