| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sulfatinib perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sulfatinib_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.171749 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.153775 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.119456 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.100826 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0918227 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0827888 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0793874 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0786478 |
| RTN4 | reticulon 4 | 0.0736376 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0711373 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0706938 |
| NAV2 | neuron navigator 2 | 0.070496 |
| CENPF | centromere protein F, 350/400kDa | 0.070392 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0662239 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0577904 |
| OGA | O-GlcNAcase | 0.0567281 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0564115 |
| ZNF292 | zinc finger protein 292 | 0.0543323 |
| MSN | moesin | 0.0538496 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0538208 |
| MKI67 | marker of proliferation Ki-67 | 0.0525774 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0485549 |
| ANLN | anillin, actin binding protein | 0.048502 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.047584 |
| SPAG9 | sperm associated antigen 9 | 0.0452301 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0431649 |
| CALD1 | caldesmon 1 | 0.0430946 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0429391 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0424212 |
| ARRDC3 | arrestin domain containing 3 | 0.0392754 |
| FN1 | fibronectin 1 | 0.0392674 |
| KIF4A | kinesin family member 4A | 0.038423 |
| TPX2 | TPX2, microtubule-associated | 0.0373869 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0367526 |
| SBF2 | SET binding factor 2 | 0.0364028 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0362572 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.035799 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0353911 |
| CCNL1 | cyclin L1 | 0.0352135 |
| ATP13A3 | ATPase type 13A3 | 0.0350858 |
| TXNRD1 | thioredoxin reductase 1 | 0.0348539 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0347186 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0335131 |
| MATR3 | matrin 3 | 0.0333333 |
| MX1 | MX dynamin-like GTPase 1 | 0.0332745 |
| SDC4 | syndecan 4 | 0.0330665 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0327218 |
| DIAPH3 | diaphanous-related formin 3 | 0.0309016 |
| GOLGA4 | golgin A4 | 0.0308129 |
| PGK1 | phosphoglycerate kinase 1 | 0.029624 |
| JMJD1C | jumonji domain containing 1C | 0.029058 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0286289 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0282087 |
| PRKCSH | protein kinase C substrate 80K-H | 0.0272713 |
| TFG | TRK-fused gene | 0.0272135 |
| THBS1 | thrombospondin 1 | 0.0271419 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0269543 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0269528 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0262011 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0259627 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.025396 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0252449 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0252023 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0250556 |
| KIF18A | kinesin family member 18A | 0.0248424 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0244965 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0240925 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0239567 |
| YBX3 | Y box binding protein 3 | 0.0238145 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0237649 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0236854 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0236082 |
| RNF145 | ring finger protein 145 | 0.0236071 |
| AFDN | afadin, adherens junction formation factor | 0.0235594 |
| NUP153 | nucleoporin 153kDa | 0.0234738 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0234563 |
| HELZ | helicase with zinc finger | 0.0234547 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0231373 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.023117 |
| ANXA5 | annexin A5 | 0.0229649 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0229161 |
| YBX1 | Y box binding protein 1 | 0.0228654 |
| GAS2L3 | growth arrest-specific 2 like 3 | 0.0228199 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0226213 |
| WTAP | Wilms tumor 1 associated protein | 0.0225219 |
| ECT2 | epithelial cell transforming 2 | 0.0224881 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0224099 |
| KIF11 | kinesin family member 11 | 0.0224062 |
| SYAP1 | synapse associated protein 1 | 0.0222102 |
| SNX9 | sorting nexin 9 | 0.0220522 |
| CKAP2 | cytoskeleton associated protein 2 | 0.021983 |
| TXNIP | thioredoxin interacting protein | 0.021706 |
| RBM39 | RNA binding motif protein 39 | 0.0216441 |
| NEK7 | NIMA-related kinase 7 | 0.0216113 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0215436 |
| NCKAP1 | NCK-associated protein 1 | 0.0215243 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0214789 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0213993 |
| YTHDC1 | YTH domain containing 1 | 0.021245 |
| EZR | ezrin | 0.0211562 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.169562 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.162493 |
| GLIS3 | GLIS family zinc finger 3 | -0.144498 |
| HMGA2 | high mobility group AT-hook 2 | -0.134141 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.129686 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.128607 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.121747 |
| FRMD4A | FERM domain containing 4A | -0.113302 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.109995 |
| CDH13 | cadherin 13 | -0.100576 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0793601 |
| IER3 | immediate early response 3 | -0.0785036 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0782953 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.076112 |
| INTS6 | integrator complex subunit 6 | -0.0708428 |
| NDRG1 | N-myc downstream regulated 1 | -0.0697609 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0678623 |
| TMSB10 | thymosin beta 10 | -0.0619441 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.060405 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0603472 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0587834 |
| EGFR | epidermal growth factor receptor | -0.0587269 |
| DIAPH2 | diaphanous-related formin 2 | -0.0575292 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0567766 |
| EFNA5 | ephrin-A5 | -0.055191 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0544653 |
| COL5A1 | collagen, type V, alpha 1 | -0.0543835 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0542597 |
| HDAC9 | histone deacetylase 9 | -0.0540545 |
| FTL | ferritin, light polypeptide | -0.0534118 |
| HLA-B | major histocompatibility complex, class I, B | -0.0519909 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0514407 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0499309 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0473273 |
| TMEM132D | transmembrane protein 132D | -0.0457626 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.04471 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0433348 |
| NAV1 | neuron navigator 1 | -0.0432504 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0417387 |
| PLIN2 | perilipin 2 | -0.0410831 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.041014 |
| LOX | lysyl oxidase | -0.0408507 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0400886 |
| RAI14 | retinoic acid induced 14 | -0.0397894 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0388113 |
| PDE10A | phosphodiesterase 10A | -0.0385635 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0376295 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.037231 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0363846 |
| SQSTM1 | sequestosome 1 | -0.0356596 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0352828 |
| ASPH | aspartate beta-hydroxylase | -0.03459 |
| TNS3 | tensin 3 | -0.0339846 |
| CTSD | cathepsin D | -0.0339809 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0338106 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0328688 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0325285 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0324081 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0321472 |
| CLMP | CXADR-like membrane protein | -0.0318964 |
| BNC2 | basonuclin 2 | -0.0318567 |
| HLA-A | major histocompatibility complex, class I, A | -0.0317118 |
| PRKCA | protein kinase C, alpha | -0.0317053 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0314216 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0310671 |
| GPC6 | glypican 6 | -0.0310315 |
| RPL23 | ribosomal protein L23 | -0.0309797 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0307675 |
| TMSB4X | thymosin beta 4, X-linked | -0.0299432 |
| VCAN | versican | -0.0296585 |
| RND3 | Rho family GTPase 3 | -0.028817 |
| SEPTIN9 | septin 9 | -0.0287319 |
| NCKAP5 | NCK-associated protein 5 | -0.0283509 |
| RPL35A | ribosomal protein L35a | -0.0281846 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0279374 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0278647 |
| CD44 | CD44 molecule (Indian blood group) | -0.0278264 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0276449 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0276235 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0274581 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0272139 |
| LDHA | lactate dehydrogenase A | -0.0269643 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0269441 |
| MT2A | metallothionein 2A | -0.0268093 |
| DTNA | dystrobrevin, alpha | -0.0265542 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0263764 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0261992 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0259198 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0256719 |
| NABP1 | nucleic acid binding protein 1 | -0.0255601 |
| ACTG1 | actin gamma 1 | -0.02553 |
| SMYD3 | SET and MYND domain containing 3 | -0.0254036 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.025344 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0251802 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0251502 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0251036 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0249472 |
| RAD51B | RAD51 paralog B | -0.0247339 |
| EHBP1 | EH domain binding protein 1 | -0.0247051 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0246541 |
