| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sulfatinib perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sulfatinib_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.208888 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0957733 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0596906 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0564092 |
| NRXN3 | neurexin 3 | 0.0563181 |
| CDH13 | cadherin 13 | 0.0524742 |
| CADM1 | cell adhesion molecule 1 | 0.0490072 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.048828 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0455449 |
| ATP13A3 | ATPase type 13A3 | 0.045137 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0361572 |
| EFNA5 | ephrin-A5 | 0.0358896 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0357765 |
| ANLN | anillin, actin binding protein | 0.0350567 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0338836 |
| IL6 | interleukin 6 | 0.0337965 |
| NKTR | natural killer cell triggering receptor | 0.0333534 |
| STC1 | stanniocalcin 1 | 0.0333266 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0326723 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0319731 |
| KIAA1217 | KIAA1217 | 0.031328 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0303377 |
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | 0.0300419 |
| GOLGA4 | golgin A4 | 0.0299673 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.02992 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0297541 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0297355 |
| TNS3 | tensin 3 | 0.0297302 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0297075 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0295509 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0293738 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0293711 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0293215 |
| SUCO | SUN domain containing ossification factor | 0.0293087 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0287824 |
| SBF2 | SET binding factor 2 | 0.0287147 |
| CLINT1 | clathrin interactor 1 | 0.0284297 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.0282166 |
| VEGFC | vascular endothelial growth factor C | 0.0280822 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.028036 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0276725 |
| TPX2 | TPX2, microtubule-associated | 0.0274206 |
| KIAA0319L | KIAA0319-like | 0.0271022 |
| RAB5A | RAB5A, member RAS oncogene family | 0.0270429 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0268823 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0268626 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0267859 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.026725 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0267141 |
| HJURP | Holliday junction recognition protein | 0.0266756 |
| FHIT | fragile histidine triad | 0.0266167 |
| FMNL2 | formin-like 2 | 0.026507 |
| TNPO3 | transportin 3 | 0.0264924 |
| CDCA2 | cell division cycle associated 2 | 0.0264763 |
| OXSR1 | oxidative stress responsive 1 | 0.0262659 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0262034 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0259874 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | 0.0259678 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0258752 |
| FNIP1 | folliculin interacting protein 1 | 0.025788 |
| FRMD6 | FERM domain containing 6 | 0.025558 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.0255064 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0254188 |
| STAM2 | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 | 0.025298 |
| PRKCSH | protein kinase C substrate 80K-H | 0.025236 |
| YBX1 | Y box binding protein 1 | 0.0251776 |
| CORO1C | coronin, actin binding protein, 1C | 0.0248629 |
| MMP12 | matrix metallopeptidase 12 | 0.0247619 |
| TMED5 | transmembrane emp24 protein transport domain containing 5 | 0.0245236 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0241186 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0239768 |
| CLDN12 | claudin 12 | 0.0238876 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0237725 |
| NUDCD3 | NudC domain containing 3 | 0.0234887 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | 0.0234875 |
| WDR1 | WD repeat domain 1 | 0.0233431 |
| ZNF133 | zinc finger protein 133 | 0.0233404 |
| KLHDC10 | kelch domain containing 10 | 0.0230896 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0230411 |
| FAM193B | family with sequence similarity 193, member B | 0.0230305 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0230282 |
| ZNF292 | zinc finger protein 292 | 0.0230169 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.023002 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0229973 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0229801 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.02283 |
| NFX1 | nuclear transcription factor, X-box binding 1 | 0.0227308 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0227279 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0227274 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.02272 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0227033 |
| ECD | ecdysoneless homolog (Drosophila) | 0.0227 |
| CA12 | carbonic anhydrase XII | 0.0224315 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0222632 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0222115 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0221902 |
| VMP1 | vacuole membrane protein 1 | 0.0221445 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.0220957 |
| OPTN | optineurin | 0.0220501 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 | 0.0220185 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.317055 |
| TMSB10 | thymosin beta 10 | -0.25698 |
| VIM | vimentin | -0.239251 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.144757 |
| FN1 | fibronectin 1 | -0.136803 |
| ENO1 | enolase 1, (alpha) | -0.126414 |
| MT2A | metallothionein 2A | -0.115417 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.115106 |
| UBC | ubiquitin C | -0.104831 |
| HLA-B | major histocompatibility complex, class I, B | -0.104178 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0987717 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0983761 |
| B2M | beta-2-microglobulin | -0.0971414 |
| CALD1 | caldesmon 1 | -0.0903293 |
| COL1A1 | collagen, type I, alpha 1 | -0.0894017 |
| POTEF | POTE ankyrin domain family, member F | -0.0853051 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0813494 |
| COL1A2 | collagen, type I, alpha 2 | -0.0725008 |
| FTL | ferritin, light polypeptide | -0.0690461 |
| LDHA | lactate dehydrogenase A | -0.0635501 |
| PTMA | prothymosin, alpha | -0.0625678 |
| CCNI | cyclin I | -0.0603336 |
| TPM4 | tropomyosin 4 | -0.0568031 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0550719 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0493958 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0487478 |
| ANXA5 | annexin A5 | -0.0486509 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0477685 |
| ACTG1 | actin gamma 1 | -0.0474053 |
| WTAP | Wilms tumor 1 associated protein | -0.0468697 |
| CALU | calumenin | -0.0459969 |
| CALR | calreticulin | -0.0443236 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0439167 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0430494 |
| MAP1B | microtubule-associated protein 1B | -0.0425255 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0421184 |
| RPL37A | ribosomal protein L37a | -0.0415963 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0413042 |
| SEPTIN7 | septin 7 | -0.0412509 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0404918 |
| PKM | pyruvate kinase, muscle | -0.0401724 |
| FLNA | filamin A, alpha | -0.0396095 |
| JUN | jun proto-oncogene | -0.0395554 |
| HLA-C | major histocompatibility complex, class I, C | -0.0389568 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0385981 |
| FLNB | filamin B, beta | -0.0378265 |
| LOX | lysyl oxidase | -0.0376634 |
| MT1X | metallothionein 1X | -0.0376421 |
| SRPK2 | SRSF protein kinase 2 | -0.0372158 |
| BSG | basigin (Ok blood group) | -0.037071 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0369949 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0366062 |
| RPS8 | ribosomal protein S8 | -0.0365348 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0362934 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0362248 |
| TOP1 | topoisomerase (DNA) I | -0.0359856 |
| CDK6 | cyclin-dependent kinase 6 | -0.034946 |
| TXNIP | thioredoxin interacting protein | -0.0348292 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.034791 |
| PRSS23 | protease, serine, 23 | -0.0346587 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0345247 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0344028 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0341824 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0337012 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | -0.0336422 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.033308 |
| RPL23 | ribosomal protein L23 | -0.0331538 |
| GANAB | glucosidase, alpha; neutral AB | -0.033055 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0327698 |
| SPAG9 | sperm associated antigen 9 | -0.0327205 |
| HLA-A | major histocompatibility complex, class I, A | -0.0325698 |
| RPLP1 | ribosomal protein, large, P1 | -0.0324395 |
| S100A10 | S100 calcium binding protein A10 | -0.0321535 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0320429 |
| S100A9 | S100 calcium binding protein A9 | -0.0318456 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.0317991 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0317827 |
| ZNF207 | zinc finger protein 207 | -0.0314379 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0311331 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | -0.030802 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0306786 |
| RIGI | RNA sensor RIG-I | -0.030306 |
| SEM1 | SEM1 26S proteasome subunit | -0.0296701 |
| THOC2 | THO complex 2 | -0.029573 |
| SEC61G | Sec61 gamma subunit | -0.029566 |
| FBN1 | fibrillin 1 | -0.0293432 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0292197 |
| RPS27A | ribosomal protein S27a | -0.0290218 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0285878 |
| GLG1 | golgi glycoprotein 1 | -0.0283679 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0281709 |
| SDC4 | syndecan 4 | -0.028088 |
| S100A6 | S100 calcium binding protein A6 | -0.0280751 |
| SMYD3 | SET and MYND domain containing 3 | -0.0277293 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0276764 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0272843 |
| SEC24D | SEC24 family member D | -0.0271633 |
| RPS4X | ribosomal protein S4, X-linked | -0.0270569 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0270205 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.026988 |
