| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sulfisoxazole perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sulfisoxazole_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PLAT | plasminogen activator, tissue | 0.148943 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.125967 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.113795 |
| VIM | vimentin | 0.108081 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.104049 |
| HDAC9 | histone deacetylase 9 | 0.0856648 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.078155 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0691486 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0658265 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0623594 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0591441 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0558157 |
| B2M | beta-2-microglobulin | 0.055602 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0521281 |
| ASPH | aspartate beta-hydroxylase | 0.0511578 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0510036 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0479901 |
| CALR | calreticulin | 0.0474619 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0471389 |
| RBM39 | RNA binding motif protein 39 | 0.0470821 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.046559 |
| GOLGA4 | golgin A4 | 0.04557 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0452059 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0432166 |
| EZR | ezrin | 0.0427958 |
| VEGFC | vascular endothelial growth factor C | 0.0423532 |
| EFNA5 | ephrin-A5 | 0.0421273 |
| RUNX1 | runt-related transcription factor 1 | 0.0418333 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0417418 |
| SMYD3 | SET and MYND domain containing 3 | 0.0414275 |
| ERBIN | erbb2 interacting protein | 0.0403068 |
| RAI1 | retinoic acid induced 1 | 0.0394156 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0391171 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0388671 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0387306 |
| GLIS3 | GLIS family zinc finger 3 | 0.0383436 |
| MB21D2 | Mab-21 domain containing 2 | 0.0382497 |
| SMAD3 | SMAD family member 3 | 0.0371431 |
| CD44 | CD44 molecule (Indian blood group) | 0.0369415 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0358061 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0357822 |
| JMJD1C | jumonji domain containing 1C | 0.0356066 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0354348 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0351323 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.034893 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0345178 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0343821 |
| TPM3 | tropomyosin 3 | 0.0342009 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0333541 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0326384 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0319748 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0316697 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0303967 |
| PRSS23 | protease, serine, 23 | 0.0297007 |
| HLA-A | major histocompatibility complex, class I, A | 0.0295519 |
| EGR1 | early growth response 1 | 0.029183 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0290894 |
| ANO6 | anoctamin 6 | 0.0289486 |
| HLA-B | major histocompatibility complex, class I, B | 0.0286435 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0281151 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0279503 |
| BPTF | bromodomain PHD finger transcription factor | 0.0278246 |
| SYTL3 | synaptotagmin-like 3 | 0.0276488 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0275369 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0274331 |
| FAM107B | family with sequence similarity 107, member B | 0.0272517 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0269636 |
| S100A10 | S100 calcium binding protein A10 | 0.0269514 |
| DST | dystonin | 0.0269013 |
| LMO7 | LIM domain 7 | 0.0264509 |
| RNF145 | ring finger protein 145 | 0.0264336 |
| MYO10 | myosin X | 0.0263906 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0261584 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0261384 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0261242 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0260769 |
| DNMBP | dynamin binding protein | 0.0258316 |
| ZNF292 | zinc finger protein 292 | 0.0256507 |
| CSTB | cystatin B (stefin B) | 0.0254962 |
| PLEC | plectin | 0.0254867 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0254045 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0250367 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0249953 |
| HIP1 | huntingtin interacting protein 1 | 0.0249014 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.024858 |
| ITSN2 | intersectin 2 | 0.024849 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0247909 |
| BCL2L1 | BCL2-like 1 | 0.0247767 |
| TPR | translocated promoter region, nuclear basket protein | 0.0243535 |
| SNX9 | sorting nexin 9 | 0.0243441 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0241768 |
| MT2A | metallothionein 2A | 0.023916 |
| TOP1 | topoisomerase (DNA) I | 0.0235465 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0234656 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0233854 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0233602 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0233306 |
| VCL | vinculin | 0.023319 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.0230494 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0228924 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.214185 |
| AHNAK | AHNAK nucleoprotein | -0.172672 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.154942 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.149525 |
| UBC | ubiquitin C | -0.149172 |
| FBN1 | fibrillin 1 | -0.134742 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.116065 |
| LOX | lysyl oxidase | -0.114033 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.10841 |
| COL5A2 | collagen, type V, alpha 2 | -0.0996687 |
| POTEF | POTE ankyrin domain family, member F | -0.0982346 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0776869 |
| AUTS2 | autism susceptibility candidate 2 | -0.0773829 |
| LDHA | lactate dehydrogenase A | -0.0610832 |
| COL5A1 | collagen, type V, alpha 1 | -0.060087 |
| COL3A1 | collagen, type III, alpha 1 | -0.0600244 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0575172 |
| COL1A2 | collagen, type I, alpha 2 | -0.0568966 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0554685 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0549186 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0537388 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0525908 |
| TMSB10 | thymosin beta 10 | -0.0480325 |
| THBS2 | thrombospondin 2 | -0.0464446 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0456883 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0426251 |
| RIGI | RNA sensor RIG-I | -0.0424985 |
| TAGLN2 | transgelin 2 | -0.0407321 |
| EGFR | epidermal growth factor receptor | -0.0402662 |
| PODXL | podocalyxin-like | -0.0401517 |
| ANXA2 | annexin A2 | -0.039657 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0389377 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0388713 |
| ACTN4 | actinin, alpha 4 | -0.038805 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0379898 |
| TNS3 | tensin 3 | -0.0379185 |
| NDRG1 | N-myc downstream regulated 1 | -0.0374764 |
| CANX | calnexin | -0.0372519 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0367848 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0360946 |
| MEIS2 | Meis homeobox 2 | -0.0359159 |
| NAV1 | neuron navigator 1 | -0.0351206 |
| ADAR | adenosine deaminase, RNA-specific | -0.0348658 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0341474 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0339001 |
| CCND1 | cyclin D1 | -0.0336688 |
| LOXL2 | lysyl oxidase-like 2 | -0.0332045 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0328836 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0325054 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0320888 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0319022 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0317158 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0316979 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0316507 |
| CDH13 | cadherin 13 | -0.0304996 |
| FLNA | filamin A, alpha | -0.0298908 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0298713 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0297019 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0285701 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0285485 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0284338 |
| PKM | pyruvate kinase, muscle | -0.027696 |
| COL18A1 | collagen, type XVIII, alpha 1 | -0.0265249 |
| JAZF1 | JAZF zinc finger 1 | -0.0263641 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.024909 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0246063 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0243982 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0242941 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0242308 |
| CAVIN1 | caveolae associated protein 1 | -0.0240513 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0236364 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.0236089 |
| SLFN5 | schlafen family member 5 | -0.0235637 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0235065 |
| CD109 | CD109 molecule | -0.023296 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.023107 |
| MNT | MAX network transcriptional repressor | -0.0228397 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0227712 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0226901 |
| TENM3 | teneurin transmembrane protein 3 | -0.0225208 |
| TUBB | tubulin, beta class I | -0.0222676 |
| MYADM | myeloid-associated differentiation marker | -0.0221551 |
| TOX | thymocyte selection-associated high mobility group box | -0.0219372 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.021897 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | -0.0218679 |
| LRRC49 | leucine rich repeat containing 49 | -0.021715 |
| FSTL1 | follistatin-like 1 | -0.0216062 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor | -0.0215601 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0214759 |
| TRIM22 | tripartite motif containing 22 | -0.0214517 |
| SP3 | Sp3 transcription factor | -0.0212695 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0210855 |
| HLA-E | major histocompatibility complex, class I, E | -0.0208264 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.0207272 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0207221 |
| MSI2 | musashi RNA-binding protein 2 | -0.020569 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0203534 |
| ATP13A3 | ATPase type 13A3 | -0.0202301 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.0202158 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0201807 |
