| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sulfisoxazole perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sulfisoxazole_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.139416 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.133285 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.123305 |
| JMJD1C | jumonji domain containing 1C | 0.0658167 |
| YBX3 | Y box binding protein 3 | 0.0654645 |
| VMP1 | vacuole membrane protein 1 | 0.0647142 |
| TPM3 | tropomyosin 3 | 0.0591413 |
| EZR | ezrin | 0.0573231 |
| AREG | amphiregulin | 0.0535014 |
| RRM2 | ribonucleotide reductase M2 | 0.0530538 |
| ASPH | aspartate beta-hydroxylase | 0.0523007 |
| RPS12 | ribosomal protein S12 | 0.0495051 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0448033 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0441389 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0439548 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0434715 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0432976 |
| TMEM41B | transmembrane protein 41B | 0.0423696 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0421907 |
| RPS3 | ribosomal protein S3 | 0.0420463 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0418278 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0418238 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0407275 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0406476 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0406374 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0393003 |
| ZNF638 | zinc finger protein 638 | 0.0388155 |
| ANXA1 | annexin A1 | 0.0382018 |
| RPL4 | ribosomal protein L4 | 0.0381882 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0379495 |
| WWOX | WW domain containing oxidoreductase | 0.0372878 |
| ENO1 | enolase 1, (alpha) | 0.0368283 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0367477 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.036603 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0360906 |
| CALR | calreticulin | 0.0357488 |
| RBM39 | RNA binding motif protein 39 | 0.0353742 |
| NHSL1 | NHS-like 1 | 0.0347934 |
| FUS | FUS RNA binding protein | 0.033471 |
| RPS2 | ribosomal protein S2 | 0.0332028 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0326684 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0325242 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0323182 |
| PCDH9 | protocadherin 9 | 0.0320433 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0319489 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0319077 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0310684 |
| CEP192 | centrosomal protein 192kDa | 0.0308577 |
| EGR1 | early growth response 1 | 0.0307614 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0302305 |
| PTMA | prothymosin, alpha | 0.0300609 |
| ZNF292 | zinc finger protein 292 | 0.0298425 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.0297089 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0296096 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0286162 |
| SMYD3 | SET and MYND domain containing 3 | 0.0278179 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0277064 |
| SET | SET nuclear proto-oncogene | 0.0276149 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0271455 |
| RTN4 | reticulon 4 | 0.0270012 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0268638 |
| PCM1 | pericentriolar material 1 | 0.0267483 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0266066 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | 0.0263905 |
| RAD51B | RAD51 paralog B | 0.0261195 |
| PTMS | parathymosin | 0.0259971 |
| R3HDM2 | R3H domain containing 2 | 0.0258544 |
| PKM | pyruvate kinase, muscle | 0.025705 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0253765 |
| AUTS2 | autism susceptibility candidate 2 | 0.0252639 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0246956 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | 0.0244752 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.024453 |
| PRKCE | protein kinase C, epsilon | 0.0244461 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0244356 |
| EHBP1 | EH domain binding protein 1 | 0.0243161 |
| PCBP2 | poly(rC) binding protein 2 | 0.0242887 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0238486 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.023602 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0235744 |
| RPS18 | ribosomal protein S18 | 0.0234927 |
| PRDX1 | peroxiredoxin 1 | 0.0234887 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0234481 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0233297 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | 0.0233159 |
| ATP11A | ATPase, class VI, type 11A | 0.0232962 |
| PHF21A | PHD finger protein 21A | 0.0229054 |
| NLGN1 | neuroligin 1 | 0.0228098 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0227609 |
| NEBL | nebulette | 0.0226857 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0226208 |
| EXOC4 | exocyst complex component 4 | 0.0224818 |
| DIAPH3 | diaphanous-related formin 3 | 0.0223638 |
| TPR | translocated promoter region, nuclear basket protein | 0.0223506 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0222918 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0222249 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0220552 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0219174 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0218461 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0216037 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.432272 |
| MMP12 | matrix metallopeptidase 12 | -0.0815689 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0801335 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0775759 |
| VIM | vimentin | -0.0716317 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0660419 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0627506 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.060994 |
| CXADR | coxsackie virus and adenovirus receptor | -0.05223 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0520013 |
| ACTG1 | actin gamma 1 | -0.0519087 |
| HMGA1 | high mobility group AT-hook 1 | -0.0517589 |
| CLDN1 | claudin 1 | -0.0489415 |
| RPLP0 | ribosomal protein, large, P0 | -0.0484345 |
| AHNAK | AHNAK nucleoprotein | -0.0475227 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0463481 |
| BCHE | butyrylcholinesterase | -0.0463446 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0460445 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0459653 |
| TMEM123 | transmembrane protein 123 | -0.0453579 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0448357 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0447365 |
| ZNF804A | zinc finger protein 804A | -0.0434934 |
| LDHA | lactate dehydrogenase A | -0.0424049 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0422969 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.042175 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.0407936 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0389492 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0386604 |
| MGAT4C | MGAT4 family, member C | -0.0380925 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0374907 |
| PLK2 | polo-like kinase 2 | -0.0370665 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0366753 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0355949 |
| RPS24 | ribosomal protein S24 | -0.0351035 |
| ZNF217 | zinc finger protein 217 | -0.0350671 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0342206 |
| MYL12B | myosin, light chain 12B, regulatory | -0.033564 |
| NEK7 | NIMA-related kinase 7 | -0.0322373 |
| TENM3 | teneurin transmembrane protein 3 | -0.0321587 |
| NABP1 | nucleic acid binding protein 1 | -0.0321197 |
| ECT2 | epithelial cell transforming 2 | -0.0316142 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0313176 |
| GASK1B | golgi associated kinase 1B | -0.0312102 |
| CDK17 | cyclin-dependent kinase 17 | -0.0299544 |
| WASF2 | WAS protein family, member 2 | -0.0290622 |
| MTAP | methylthioadenosine phosphorylase | -0.0288682 |
| RPS23 | ribosomal protein S23 | -0.0280367 |
| KLF6 | Kruppel-like factor 6 | -0.0277626 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0273335 |
| WDR45B | WD repeat domain 45B | -0.0268762 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0266692 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0265633 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0261768 |
| POTEF | POTE ankyrin domain family, member F | -0.026147 |
| RPL27A | ribosomal protein L27a | -0.0260695 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0260111 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0259197 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0255534 |
| MYPN | myopalladin | -0.0255236 |
| UBC | ubiquitin C | -0.025521 |
| OXR1 | oxidation resistance 1 | -0.025321 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0249766 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | -0.0248332 |
| CANX | calnexin | -0.0241861 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.02371 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0234539 |
| CDK6 | cyclin-dependent kinase 6 | -0.0233578 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0231185 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0229842 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0229504 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | -0.0227799 |
| KLHL24 | kelch-like family member 24 | -0.0223033 |
| H3-3B | H3.3 histone B | -0.0222109 |
| RPS15 | ribosomal protein S15 | -0.0221412 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0221344 |
| RPL6 | ribosomal protein L6 | -0.0216891 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0216607 |
| S100A6 | S100 calcium binding protein A6 | -0.0216161 |
| CLTC | clathrin, heavy chain (Hc) | -0.0215901 |
| WDR43 | WD repeat domain 43 | -0.021543 |
| RPL19 | ribosomal protein L19 | -0.0213852 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0213768 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0213459 |
| ELP4 | elongator acetyltransferase complex subunit 4 | -0.0212934 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0212804 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0211629 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0210242 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0208488 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.020718 |
| RPL32 | ribosomal protein L32 | -0.0206349 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0205639 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0205059 |
| TUBA1B | tubulin, alpha 1b | -0.0204561 |
| VPS8 | vacuolar protein sorting 8 homolog (S. cerevisiae) | -0.020276 |
| MOB1A | MOB kinase activator 1A | -0.0201955 |
| IL6ST | interleukin 6 signal transducer | -0.0201885 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | -0.0201776 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.020101 |
| TGIF1 | TGFB-induced factor homeobox 1 | -0.0200256 |
