| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sulfisoxazole perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Sulfisoxazole_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.0999986 |
| FMN1 | formin 1 | 0.0760213 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0674445 |
| TLE4 | transducin-like enhancer of split 4 | 0.0606454 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.059267 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.056576 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0559738 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.049482 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0487959 |
| DST | dystonin | 0.048242 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0447914 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0423263 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0402048 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0401409 |
| SMYD3 | SET and MYND domain containing 3 | 0.037312 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0367165 |
| VMP1 | vacuole membrane protein 1 | 0.0353582 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0352537 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.035094 |
| EGR1 | early growth response 1 | 0.035088 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0342971 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0339399 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0330615 |
| IGF2 | insulin-like growth factor 2 | 0.0328777 |
| MEIS2 | Meis homeobox 2 | 0.0327206 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0325661 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0324069 |
| VEGFA | vascular endothelial growth factor A | 0.0322329 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.031855 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0317895 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0311964 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0307355 |
| ZNF638 | zinc finger protein 638 | 0.0304721 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0304136 |
| IRS1 | insulin receptor substrate 1 | 0.0300641 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0300472 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0297299 |
| GOLGB1 | golgin B1 | 0.0293241 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0288836 |
| BPTF | bromodomain PHD finger transcription factor | 0.0288155 |
| SNX14 | sorting nexin 14 | 0.0281232 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0273859 |
| PDE10A | phosphodiesterase 10A | 0.0266721 |
| THBS1 | thrombospondin 1 | 0.0264175 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0262304 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0261894 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0257074 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0254248 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0249679 |
| RPL4 | ribosomal protein L4 | 0.0249221 |
| MYO1E | myosin IE | 0.0248212 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0248023 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0246256 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0245908 |
| DIAPH2 | diaphanous-related formin 2 | 0.0244848 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0242946 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0238707 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0238568 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0238461 |
| SIK2 | salt-inducible kinase 2 | 0.0235515 |
| ITGAV | integrin, alpha V | 0.0233801 |
| TMEM14B | transmembrane protein 14B | 0.0232827 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0232302 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0231908 |
| GPC5 | glypican 5 | 0.0228798 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0228008 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0226685 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0225981 |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 | 0.0222319 |
| SBF2 | SET binding factor 2 | 0.0220975 |
| ZFHX3 | zinc finger homeobox 3 | 0.0220765 |
| STK38L | serine/threonine kinase 38 like | 0.0220338 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.0218 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0214731 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0214404 |
| PLAT | plasminogen activator, tissue | 0.0214101 |
| RIGI | RNA sensor RIG-I | 0.0213357 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0210692 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0209906 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0209612 |
| INHBA | inhibin, beta A | 0.0207709 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.020632 |
| PDE8A | phosphodiesterase 8A | 0.0204723 |
| GLCCI1 | glucocorticoid induced 1 | 0.0204619 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0203453 |
| TFCP2 | transcription factor CP2 | 0.0203209 |
| BCL2L13 | BCL2-like 13 (apoptosis facilitator) | 0.0203029 |
| RAD51B | RAD51 paralog B | 0.0202899 |
| KCNT2 | potassium channel, sodium activated subfamily T, member 2 | 0.0202801 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0202683 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0202195 |
| TLN1 | talin 1 | 0.0201867 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0201437 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0199948 |
| DHX40 | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 0.0199693 |
| PRKCE | protein kinase C, epsilon | 0.0199016 |
| HOMER1 | homer scaffolding protein 1 | 0.0197899 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0195035 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0194657 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0194034 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.386678 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.225066 |
| NRG1 | neuregulin 1 | -0.129135 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.103302 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0950246 |
| VIM | vimentin | -0.0905017 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0645919 |
| TRIB2 | tribbles pseudokinase 2 | -0.0627323 |
| PTMA | prothymosin, alpha | -0.0611933 |
| MAP1B | microtubule-associated protein 1B | -0.0579495 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0576562 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0575007 |
| H3-3B | H3.3 histone B | -0.054668 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.048547 |
| FAM13A | family with sequence similarity 13, member A | -0.04832 |
| CADM2 | cell adhesion molecule 2 | -0.0478987 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0473535 |
| HELZ | helicase with zinc finger | -0.0452276 |
| ACTG1 | actin gamma 1 | -0.0440366 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0438889 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0428356 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0423962 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0422496 |
| RPL38 | ribosomal protein L38 | -0.0412558 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.04103 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0396934 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0396282 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0395973 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0394545 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0394083 |
| HIP1 | huntingtin interacting protein 1 | -0.0392647 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0390462 |
| AHNAK | AHNAK nucleoprotein | -0.0390287 |
| RPL35A | ribosomal protein L35a | -0.0381172 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0377441 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0371492 |
| RPLP1 | ribosomal protein, large, P1 | -0.036553 |
| RPLP0 | ribosomal protein, large, P0 | -0.0361681 |
| WDR45B | WD repeat domain 45B | -0.0358117 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0356701 |
| RPL19 | ribosomal protein L19 | -0.0347374 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0346634 |
| QKI | QKI, KH domain containing, RNA binding | -0.0345818 |
| LPIN1 | lipin 1 | -0.0336235 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0333407 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0330801 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | -0.0326695 |
| COL3A1 | collagen, type III, alpha 1 | -0.0324667 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0323002 |
| RPS11 | ribosomal protein S11 | -0.0321936 |
| RPS24 | ribosomal protein S24 | -0.0320929 |
| CENPF | centromere protein F, 350/400kDa | -0.0319907 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0309854 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0307604 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0305513 |
| DTNA | dystrobrevin, alpha | -0.0305247 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0304127 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0300124 |
| COL1A1 | collagen, type I, alpha 1 | -0.029613 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.029079 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0287792 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0284062 |
| COL4A5 | collagen, type IV, alpha 5 | -0.028354 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.028254 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0280488 |
| COPA | coatomer protein complex, subunit alpha | -0.0280421 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0275074 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0273248 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.027275 |
| CCND1 | cyclin D1 | -0.0266886 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0266405 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0265876 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0264335 |
| SPAG9 | sperm associated antigen 9 | -0.0264273 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0263311 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0259988 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0259977 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0256654 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0256418 |
| USP3 | ubiquitin specific peptidase 3 | -0.0253817 |
| RPL32 | ribosomal protein L32 | -0.0250438 |
| PCDH9 | protocadherin 9 | -0.0249748 |
| UBC | ubiquitin C | -0.0249364 |
| CCDC47 | coiled-coil domain containing 47 | -0.0248509 |
| NOP58 | NOP58 ribonucleoprotein | -0.0247783 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0247588 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0246452 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0244412 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0242579 |
| CLINT1 | clathrin interactor 1 | -0.0242477 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0241873 |
| ANXA2 | annexin A2 | -0.0239035 |
| HMGB2 | high mobility group box 2 | -0.0238834 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0238804 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0236648 |
| CUX1 | cut-like homeobox 1 | -0.0236512 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0235973 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0234979 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | -0.0233986 |
| KLHL5 | kelch-like family member 5 | -0.023134 |
