| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sulfisoxazole perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sulfisoxazole_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.186407 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.104889 |
| MYO1E | myosin IE | 0.0921912 |
| TMC5 | transmembrane channel-like 5 | 0.0639037 |
| SMAD3 | SMAD family member 3 | 0.0574364 |
| EZR | ezrin | 0.0568005 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0552228 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0550662 |
| TJP1 | tight junction protein 1 | 0.0511228 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0509355 |
| LCN2 | lipocalin 2 | 0.0503021 |
| EGR1 | early growth response 1 | 0.0502068 |
| MLPH | melanophilin | 0.0477651 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0476321 |
| PHF3 | PHD finger protein 3 | 0.0474838 |
| JUN | jun proto-oncogene | 0.0465746 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0450958 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.042769 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0424307 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0413083 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0403524 |
| DIAPH1 | diaphanous-related formin 1 | 0.0400584 |
| SEPTIN9 | septin 9 | 0.0378034 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0373767 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.03721 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0363901 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0363637 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0360419 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.035011 |
| AREG | amphiregulin | 0.0344934 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0339628 |
| SDC4 | syndecan 4 | 0.0326789 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0326555 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0321264 |
| BCL2L1 | BCL2-like 1 | 0.0320421 |
| ERBIN | erbb2 interacting protein | 0.0319905 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0319188 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0316215 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0303239 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0296911 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0295342 |
| MCL1 | myeloid cell leukemia 1 | 0.0294734 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0294636 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0291901 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.028926 |
| RPL4 | ribosomal protein L4 | 0.0289225 |
| VMP1 | vacuole membrane protein 1 | 0.0287753 |
| MUC13 | mucin 13, cell surface associated | 0.0284287 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.028212 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.028119 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0276114 |
| JUP | junction plakoglobin | 0.02753 |
| SLK | STE20-like kinase | 0.0273247 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0272728 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.027269 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.026978 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0266978 |
| DHFR | dihydrofolate reductase | 0.0265603 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0264212 |
| RPS6 | ribosomal protein S6 | 0.026335 |
| YBX3 | Y box binding protein 3 | 0.0253611 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0253271 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0252463 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0250752 |
| CLDN4 | claudin 4 | 0.0248342 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0244125 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0242581 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0236853 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.023333 |
| LIMA1 | LIM domain and actin binding 1 | 0.0233076 |
| CYTH1 | cytohesin 1 | 0.0232241 |
| RBM39 | RNA binding motif protein 39 | 0.0231916 |
| FHL2 | four and a half LIM domains 2 | 0.0231703 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | 0.0229607 |
| KIF13B | kinesin family member 13B | 0.0228471 |
| FOXO1 | forkhead box O1 | 0.0228113 |
| VCL | vinculin | 0.0227525 |
| PSEN1 | presenilin 1 | 0.0227176 |
| SET | SET nuclear proto-oncogene | 0.0225795 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0219904 |
| RPS12 | ribosomal protein S12 | 0.0219179 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0216783 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0214231 |
| ITPKC | inositol-trisphosphate 3-kinase C | 0.0213458 |
| STK24 | serine/threonine kinase 24 | 0.0213213 |
| TPM3 | tropomyosin 3 | 0.020976 |
| MYO6 | myosin VI | 0.0207314 |
| EHBP1 | EH domain binding protein 1 | 0.0205847 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | 0.0205813 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0204486 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0201807 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 0.020039 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.020013 |
| ABHD17C | abhydrolase domain containing 17C | 0.0198701 |
| DUSP10 | dual specificity phosphatase 10 | 0.0197589 |
| EFNB2 | ephrin-B2 | 0.0196536 |
| ACTN4 | actinin, alpha 4 | 0.0196506 |
| DSPP | dentin sialophosphoprotein | 0.0196095 |
| FHIT | fragile histidine triad | 0.0196019 |
| KIF5B | kinesin family member 5B | 0.0194426 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.193537 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.150933 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.150097 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.109237 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.106952 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.100241 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0982323 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0905708 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0821392 |
| TXNIP | thioredoxin interacting protein | -0.0773777 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0760154 |
| B2M | beta-2-microglobulin | -0.0754811 |
| RNF213 | ring finger protein 213 | -0.0741927 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0737339 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0725976 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0724027 |
| PERP | PERP, TP53 apoptosis effector | -0.071109 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0704096 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0661978 |
| NDRG1 | N-myc downstream regulated 1 | -0.0646168 |
| LYZ | lysozyme | -0.0625105 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0582575 |
| UBC | ubiquitin C | -0.058206 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0565311 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0540593 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0529751 |
| CANX | calnexin | -0.0525943 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0518522 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0518121 |
| RUNX1 | runt-related transcription factor 1 | -0.0508114 |
| FNIP1 | folliculin interacting protein 1 | -0.048763 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.04853 |
| DIAPH3 | diaphanous-related formin 3 | -0.0482843 |
| LDHA | lactate dehydrogenase A | -0.0481181 |
| RIGI | RNA sensor RIG-I | -0.0477895 |
| AGR2 | anterior gradient 2 | -0.0458785 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0455789 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0445907 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0437756 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -0.0434938 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0426543 |
| SP100 | SP100 nuclear antigen | -0.0422504 |
| H1-0 | H1.0 linker histone | -0.0421555 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0414315 |
| XAF1 | XIAP associated factor 1 | -0.0404431 |
| ABLIM1 | actin binding LIM protein 1 | -0.0402309 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0400753 |
| NPSR1 | neuropeptide S receptor 1 | -0.0397236 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0395286 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0388946 |
| APOL6 | apolipoprotein L, 6 | -0.0382035 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.038157 |
| SEC24D | SEC24 family member D | -0.0376023 |
| PTEN | phosphatase and tensin homolog | -0.0375453 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0375318 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0373043 |
| NUCB2 | nucleobindin 2 | -0.0366942 |
| H3-3B | H3.3 histone B | -0.0355774 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0355317 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0352585 |
| MKI67 | marker of proliferation Ki-67 | -0.0347033 |
| IRF1 | interferon regulatory factor 1 | -0.0340751 |
| PTMA | prothymosin, alpha | -0.0340666 |
| HLA-E | major histocompatibility complex, class I, E | -0.0337515 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.0335401 |
| TMEM263 | transmembrane protein 263 | -0.0333536 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0333491 |
| SMC4 | structural maintenance of chromosomes 4 | -0.033237 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0327146 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0323513 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0321376 |
| MX1 | MX dynamin-like GTPase 1 | -0.0321234 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0318387 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0315979 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0315963 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0315156 |
| AHI1 | Abelson helper integration site 1 | -0.0313784 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.0313082 |
| PKM | pyruvate kinase, muscle | -0.03123 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0308974 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.030785 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.030599 |
| HBS1L | HBS1-like translational GTPase | -0.0305275 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0302145 |
| TFG | TRK-fused gene | -0.0301978 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0300317 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0299792 |
| MECOM | MDS1 and EVI1 complex locus | -0.0298123 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0294064 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0293275 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0292288 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0289803 |
| CTSD | cathepsin D | -0.0288687 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0286676 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0283858 |
| WASF2 | WAS protein family, member 2 | -0.0281626 |
| EPB41 | erythrocyte membrane protein band 4.1 | -0.0280333 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0279926 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0279819 |
| UBAC2 | UBA domain containing 2 | -0.0277071 |
