| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sulfisoxazole perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Sulfisoxazole_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.229638 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.144905 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.108142 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0905511 |
| INHBA | inhibin, beta A | 0.0700749 |
| PLEC | plectin | 0.0699298 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0698112 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0697281 |
| CALR | calreticulin | 0.0672341 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0638785 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0609181 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0606539 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0595359 |
| VEGFA | vascular endothelial growth factor A | 0.0561609 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0541621 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.049413 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0490096 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0487958 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0476308 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0476304 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0461292 |
| STC1 | stanniocalcin 1 | 0.0461279 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0447744 |
| SDC2 | syndecan 2 | 0.0446844 |
| HLA-A | major histocompatibility complex, class I, A | 0.0443165 |
| MYO10 | myosin X | 0.0433821 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0433439 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0423581 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0418721 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0415221 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.041035 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0408253 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0399358 |
| ATP13A3 | ATPase type 13A3 | 0.0385354 |
| COL3A1 | collagen, type III, alpha 1 | 0.0385141 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0380332 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0378144 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0375203 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0371971 |
| RBM39 | RNA binding motif protein 39 | 0.0369031 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0342983 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0342388 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0339459 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0337319 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0332847 |
| HLA-B | major histocompatibility complex, class I, B | 0.0331851 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0324981 |
| ENO1 | enolase 1, (alpha) | 0.0323792 |
| FMNL2 | formin-like 2 | 0.0322735 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0313369 |
| NAV2 | neuron navigator 2 | 0.0313211 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0311426 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.030384 |
| RPS2 | ribosomal protein S2 | 0.0303803 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0301714 |
| RPS12 | ribosomal protein S12 | 0.0295321 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0293711 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.029343 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0292202 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0290433 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0283871 |
| ANGPTL4 | angiopoietin-like 4 | 0.0281398 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0274967 |
| ASPH | aspartate beta-hydroxylase | 0.0273875 |
| PTMA | prothymosin, alpha | 0.0273612 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0269989 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.026225 |
| ANXA1 | annexin A1 | 0.0259603 |
| MED13L | mediator complex subunit 13-like | 0.0259511 |
| MYO1B | myosin IB | 0.0259352 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0259305 |
| TMF1 | TATA element modulatory factor 1 | 0.0254674 |
| DSPP | dentin sialophosphoprotein | 0.0254068 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0253238 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0252776 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0252498 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0251673 |
| VMP1 | vacuole membrane protein 1 | 0.0244257 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0243829 |
| RPL11 | ribosomal protein L11 | 0.0242523 |
| RPL26 | ribosomal protein L26 | 0.0240116 |
| ADM | adrenomedullin | 0.0238546 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0237688 |
| SP100 | SP100 nuclear antigen | 0.0234954 |
| TMSB4X | thymosin beta 4, X-linked | 0.0234436 |
| ZNF292 | zinc finger protein 292 | 0.0234336 |
| FLNB | filamin B, beta | 0.0234051 |
| JAK1 | Janus kinase 1 | 0.0232246 |
| RASA2 | RAS p21 protein activator 2 | 0.0232108 |
| OPTN | optineurin | 0.0231696 |
| RPS18 | ribosomal protein S18 | 0.0231275 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0230027 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0229261 |
| RPL4 | ribosomal protein L4 | 0.0229078 |
| CCNY | cyclin Y | 0.0228586 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0227412 |
| RPS6 | ribosomal protein S6 | 0.0227054 |
| TPM3 | tropomyosin 3 | 0.0226771 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0226175 |
| SFTPA2 | surfactant protein A2 | 0.0225096 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.245474 |
| FN1 | fibronectin 1 | -0.221128 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.132771 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.118342 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.116275 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.104589 |
| MT2A | metallothionein 2A | -0.100772 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0753445 |
| FBN1 | fibrillin 1 | -0.0749182 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0720795 |
| LDHA | lactate dehydrogenase A | -0.0652991 |
| VIM | vimentin | -0.06262 |
| CDH13 | cadherin 13 | -0.0609677 |
| NDRG1 | N-myc downstream regulated 1 | -0.0609202 |
| CLIC4 | chloride intracellular channel 4 | -0.0531856 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0508769 |
| MAP1B | microtubule-associated protein 1B | -0.0497617 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0483361 |
| PRELID2 | PRELI domain containing 2 | -0.046509 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0441221 |
| AHNAK | AHNAK nucleoprotein | -0.0416083 |
| GLIS3 | GLIS family zinc finger 3 | -0.0407253 |
| ACTG1 | actin gamma 1 | -0.0399315 |
| TMSB10 | thymosin beta 10 | -0.0390374 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0380312 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0377686 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0373908 |
| PALLD | palladin, cytoskeletal associated protein | -0.0366256 |
| TPM4 | tropomyosin 4 | -0.0365805 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0364221 |
| FTL | ferritin, light polypeptide | -0.0364066 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0360293 |
| WASF2 | WAS protein family, member 2 | -0.0353178 |
| COL1A1 | collagen, type I, alpha 1 | -0.0351883 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0351192 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0339555 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0336425 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0330961 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0327489 |
| EHD2 | EH-domain containing 2 | -0.0321855 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0315069 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0312645 |
| POSTN | periostin, osteoblast specific factor | -0.0310027 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0306945 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0298734 |
| MAP4 | microtubule-associated protein 4 | -0.0295592 |
| BNC2 | basonuclin 2 | -0.0291845 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0291405 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0289069 |
| TMEM263 | transmembrane protein 263 | -0.0288364 |
| TAPBP | TAP binding protein (tapasin) | -0.0287987 |
| CALD1 | caldesmon 1 | -0.0281247 |
| UBC | ubiquitin C | -0.0277754 |
| TENM3 | teneurin transmembrane protein 3 | -0.0274716 |
| SBF2 | SET binding factor 2 | -0.0268359 |
| RIGI | RNA sensor RIG-I | -0.0268082 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0266308 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0264938 |
| NABP1 | nucleic acid binding protein 1 | -0.0264687 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0264023 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.026137 |
| PRR16 | proline rich 16 | -0.0261055 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0258949 |
| RNF220 | ring finger protein 220 | -0.0257677 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0255824 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0252147 |
| PPP3CC | protein phosphatase 3, catalytic subunit, gamma isozyme | -0.0251662 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0246942 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0245955 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0244127 |
| MT1X | metallothionein 1X | -0.024063 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0240493 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0239359 |
| TENM1 | teneurin transmembrane protein 1 | -0.0239257 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.023854 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0236474 |
| NBEAL1 | neurobeachin-like 1 | -0.0236243 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0235141 |
| SMYD3 | SET and MYND domain containing 3 | -0.0234495 |
| GOLGB1 | golgin B1 | -0.0234315 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0232645 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0230869 |
| CANX | calnexin | -0.0230453 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0227134 |
| EBF1 | early B-cell factor 1 | -0.0225259 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.02241 |
| NCOA2 | nuclear receptor coactivator 2 | -0.022183 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0220768 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0220223 |
| EXOC4 | exocyst complex component 4 | -0.0214251 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0213977 |
| NAV1 | neuron navigator 1 | -0.021172 |
| NREP | neuronal regeneration related protein | -0.0211018 |
| FOXP1 | forkhead box P1 | -0.0210178 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.021014 |
| FRMD4A | FERM domain containing 4A | -0.020772 |
| SULF1 | sulfatase 1 | -0.0206821 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0204953 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0204128 |
| NRP1 | neuropilin 1 | -0.0201091 |
