| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sulfisoxazole perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Sulfisoxazole_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.16309 |
| DSPP | dentin sialophosphoprotein | 0.127023 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.117653 |
| MT2A | metallothionein 2A | 0.105854 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0977522 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0919511 |
| SVIL | supervillin | 0.0906297 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0889141 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0876152 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0822787 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.0787548 |
| ENO1 | enolase 1, (alpha) | 0.0779587 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0774954 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0737183 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.062838 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.061446 |
| FAM107B | family with sequence similarity 107, member B | 0.0597708 |
| ASPH | aspartate beta-hydroxylase | 0.0589127 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0580262 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0544464 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0519894 |
| FMNL2 | formin-like 2 | 0.0515623 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0493704 |
| RPL4 | ribosomal protein L4 | 0.0467116 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.044983 |
| DST | dystonin | 0.0435892 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0432167 |
| STC2 | stanniocalcin 2 | 0.0431879 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0431547 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0423724 |
| TNS1 | tensin 1 | 0.0420527 |
| NDRG1 | N-myc downstream regulated 1 | 0.0409712 |
| VEGFA | vascular endothelial growth factor A | 0.039834 |
| KIF1B | kinesin family member 1B | 0.0382384 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0373976 |
| INTS6 | integrator complex subunit 6 | 0.03694 |
| FKTN | fukutin | 0.0366938 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0363652 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.0354597 |
| FRMD5 | FERM domain containing 5 | 0.0354074 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0341149 |
| H1-0 | H1.0 linker histone | 0.0337314 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0324084 |
| DTNA | dystrobrevin, alpha | 0.0323678 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.0309923 |
| RAD51B | RAD51 paralog B | 0.0308946 |
| KYNU | kynureninase | 0.0306287 |
| RPS18 | ribosomal protein S18 | 0.0305032 |
| SERTAD2 | SERTA domain containing 2 | 0.0304464 |
| ZNF292 | zinc finger protein 292 | 0.0298838 |
| ATXN1 | ataxin 1 | 0.0297477 |
| KIAA1217 | KIAA1217 | 0.0294163 |
| TLE4 | transducin-like enhancer of split 4 | 0.0292816 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0292564 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.029059 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0288907 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0277735 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0270685 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0267508 |
| FOXP1 | forkhead box P1 | 0.0266422 |
| PLEC | plectin | 0.0260449 |
| FERMT2 | fermitin family member 2 | 0.0258375 |
| OGA | O-GlcNAcase | 0.0258203 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | 0.0257332 |
| LMO7 | LIM domain 7 | 0.0255984 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0254933 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0253156 |
| CAPRIN2 | caprin family member 2 | 0.0250881 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0250653 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.024765 |
| ANO6 | anoctamin 6 | 0.0245716 |
| TMEM14B | transmembrane protein 14B | 0.024509 |
| EZR | ezrin | 0.0243356 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0241525 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0239036 |
| ZNF638 | zinc finger protein 638 | 0.02388 |
| RPL3 | ribosomal protein L3 | 0.0237316 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 0.0234283 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0232307 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0229258 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0229118 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0228022 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0227554 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0226575 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0225531 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0225518 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0225254 |
| PRELID2 | PRELI domain containing 2 | 0.0225047 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0224175 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0220473 |
| TPD52 | tumor protein D52 | 0.0219086 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0215464 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0214404 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.0213786 |
| FAM13A | family with sequence similarity 13, member A | 0.0213043 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0210161 |
| HLA-A | major histocompatibility complex, class I, A | 0.02101 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0209635 |
| FNIP1 | folliculin interacting protein 1 | 0.0205833 |
| TLN1 | talin 1 | 0.0205729 |
| Symbol | Name | Standardized Value |
|---|---|---|
| APOB | apolipoprotein B | -0.225185 |
| FN1 | fibronectin 1 | -0.151265 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.131457 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.121948 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.115412 |
| FNDC3B | fibronectin type III domain containing 3B | -0.114031 |
| IGF2 | insulin-like growth factor 2 | -0.108748 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0935864 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0918605 |
| GPC3 | glypican 3 | -0.0914106 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0851528 |
| GPC6 | glypican 6 | -0.0837037 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0835676 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | -0.0833891 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0784696 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.074073 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0716889 |
| ITGAV | integrin, alpha V | -0.0711747 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.070082 |
| C3 | complement component 3 | -0.0696943 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0659561 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0647186 |
| A2M | alpha-2-macroglobulin | -0.0636341 |
| CP | ceruloplasmin (ferroxidase) | -0.0633599 |
| TRIM26 | tripartite motif containing 26 | -0.0593176 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0581701 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0571898 |
| APOA2 | apolipoprotein A-II | -0.05025 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0490166 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.047044 |
| MBNL3 | muscleblind-like splicing regulator 3 | -0.0461789 |
| MRTFA | myocardin related transcription factor A | -0.0427869 |
| SESTD1 | SEC14 and spectrin domains 1 | -0.0427146 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0417503 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0415311 |
| RPS24 | ribosomal protein S24 | -0.0415178 |
| OSMR | oncostatin M receptor | -0.0409054 |
| EGR1 | early growth response 1 | -0.0407956 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0406164 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0404404 |
| PERP | PERP, TP53 apoptosis effector | -0.0396692 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0395605 |
| GDF15 | growth differentiation factor 15 | -0.0395318 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0394421 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.039225 |
| DNAH17 | dynein, axonemal, heavy chain 17 | -0.0389345 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0387832 |
| VCL | vinculin | -0.0382112 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0380542 |
| ZFHX3 | zinc finger homeobox 3 | -0.0367409 |
| MSI2 | musashi RNA-binding protein 2 | -0.0366475 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0361062 |
| IER3 | immediate early response 3 | -0.035354 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0352379 |
| RPLP0 | ribosomal protein, large, P0 | -0.0350487 |
| TULP4 | tubby like protein 4 | -0.0343833 |
| ARL5A | ADP-ribosylation factor-like 5A | -0.0343347 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0339821 |
| TMEM123 | transmembrane protein 123 | -0.033565 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0332759 |
| RPL11 | ribosomal protein L11 | -0.0331307 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0329401 |
| RPL34 | ribosomal protein L34 | -0.032689 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0325523 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.0322245 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0320441 |
| ACSS3 | acyl-CoA synthetase short-chain family member 3 | -0.0317831 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0317621 |
| AHSG | alpha-2-HS-glycoprotein | -0.0312498 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0300773 |
| CPE | carboxypeptidase E | -0.0300454 |
| RPLP1 | ribosomal protein, large, P1 | -0.0300404 |
| LYZ | lysozyme | -0.0300079 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0299169 |
| RNF213 | ring finger protein 213 | -0.0297883 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0296172 |
| AMBP | alpha-1-microglobulin/bikunin precursor | -0.0294247 |
| PTCHD4 | patched domain containing 4 | -0.0292665 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0291165 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | -0.0291079 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0290468 |
| RPL35A | ribosomal protein L35a | -0.028916 |
| GNAS | GNAS complex locus | -0.0288828 |
| H3-3B | H3.3 histone B | -0.0279858 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0279675 |
| GLG1 | golgi glycoprotein 1 | -0.0277698 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.0277373 |
| DOK6 | docking protein 6 | -0.0276941 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | -0.0269325 |
| LMCD1 | LIM and cysteine-rich domains 1 | -0.0269161 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.0267002 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0266226 |
| RRBP1 | ribosome binding protein 1 | -0.0265858 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0265476 |
| MX2 | MX dynamin-like GTPase 2 | -0.0264888 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0262306 |
| WTAP | Wilms tumor 1 associated protein | -0.0259185 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | -0.025784 |
| EHBP1 | EH domain binding protein 1 | -0.0257821 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.0257339 |
