| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sulfisoxazole perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Sulfisoxazole_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MEF2A | myocyte enhancer factor 2A | 0.064135 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0623492 |
| MT2A | metallothionein 2A | 0.0593077 |
| LMO7 | LIM domain 7 | 0.0571445 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0563977 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0546513 |
| OSMR | oncostatin M receptor | 0.0522992 |
| SLK | STE20-like kinase | 0.0517706 |
| PLAT | plasminogen activator, tissue | 0.0510557 |
| BCL2L1 | BCL2-like 1 | 0.0509128 |
| RPL4 | ribosomal protein L4 | 0.050036 |
| TGM2 | transglutaminase 2 | 0.0485952 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0463814 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.045258 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0444231 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0442 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0426303 |
| B2M | beta-2-microglobulin | 0.0426003 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0424566 |
| TPM3 | tropomyosin 3 | 0.0420411 |
| HLA-B | major histocompatibility complex, class I, B | 0.0416547 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0410381 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0410089 |
| ITGB4 | integrin, beta 4 | 0.0396569 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.038707 |
| IFI44L | interferon-induced protein 44-like | 0.0385505 |
| HLA-A | major histocompatibility complex, class I, A | 0.0380284 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0373375 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0365966 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0361734 |
| EZR | ezrin | 0.0360287 |
| YBX3 | Y box binding protein 3 | 0.0359311 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0354338 |
| ASPH | aspartate beta-hydroxylase | 0.0354243 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0347108 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0345217 |
| PLEC | plectin | 0.0337378 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0335494 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0335421 |
| TXNIP | thioredoxin interacting protein | 0.0334774 |
| DSPP | dentin sialophosphoprotein | 0.0334026 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0326662 |
| DHFR | dihydrofolate reductase | 0.0323043 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0319237 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0318602 |
| KRT17 | keratin 17, type I | 0.0317654 |
| RPS2 | ribosomal protein S2 | 0.0302642 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0302389 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0300435 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0300045 |
| SEPTIN9 | septin 9 | 0.0300014 |
| BARX2 | BARX homeobox 2 | 0.029403 |
| RBM39 | RNA binding motif protein 39 | 0.0291797 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0284027 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0279639 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0278157 |
| ANXA11 | annexin A11 | 0.0275354 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 0.0274581 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.0274434 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0270203 |
| LUZP1 | leucine zipper protein 1 | 0.0269457 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0269341 |
| ANGPTL4 | angiopoietin-like 4 | 0.0269104 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.026752 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.026724 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0264632 |
| RIN2 | Ras and Rab interactor 2 | 0.0264456 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0261232 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0260556 |
| PDLIM1 | PDZ and LIM domain 1 | 0.025996 |
| VIM | vimentin | 0.0259287 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0259207 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0257406 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0254286 |
| FOXP1 | forkhead box P1 | 0.0253794 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0253224 |
| TNS4 | tensin 4 | 0.0252545 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0252472 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0251947 |
| TXNRD1 | thioredoxin reductase 1 | 0.0250092 |
| TMF1 | TATA element modulatory factor 1 | 0.0249237 |
| IFI44 | interferon-induced protein 44 | 0.024751 |
| OGA | O-GlcNAcase | 0.0246218 |
| OPTN | optineurin | 0.0245147 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0243184 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.024244 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0239313 |
| RPL26 | ribosomal protein L26 | 0.0239179 |
| RPS12 | ribosomal protein S12 | 0.0238254 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0235665 |
| AOPEP | aminopeptidase O (putative) | 0.0234481 |
| RPS18 | ribosomal protein S18 | 0.0232861 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0232706 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0231033 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0230713 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0229301 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0225726 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0224454 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0221356 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0219575 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.238104 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.205878 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.139666 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.12721 |
| INTS6 | integrator complex subunit 6 | -0.114124 |
| DPYD | dihydropyrimidine dehydrogenase | -0.10399 |
| AHNAK | AHNAK nucleoprotein | -0.0968135 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0956876 |
| SULF1 | sulfatase 1 | -0.0882014 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0866891 |
| POTEF | POTE ankyrin domain family, member F | -0.0844898 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0771685 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0705403 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0685843 |
| S100A10 | S100 calcium binding protein A10 | -0.0681398 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0677198 |
| LDHA | lactate dehydrogenase A | -0.0668472 |
| HM13 | histocompatibility (minor) 13 | -0.0649941 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0638803 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0614686 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0599044 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0561077 |
| GNAS | GNAS complex locus | -0.0507429 |
| MORF4L2 | mortality factor 4 like 2 | -0.0499153 |
| CANX | calnexin | -0.0498625 |
| NDRG1 | N-myc downstream regulated 1 | -0.049812 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0495652 |
| RPS24 | ribosomal protein S24 | -0.0495485 |
| SQSTM1 | sequestosome 1 | -0.0486295 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.047452 |
| RPS25 | ribosomal protein S25 | -0.0469316 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0467832 |
| ANXA2 | annexin A2 | -0.0438898 |
| STC1 | stanniocalcin 1 | -0.0421832 |
| RPS23 | ribosomal protein S23 | -0.0417567 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0404335 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0402912 |
| RPS13 | ribosomal protein S13 | -0.0394809 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0392386 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0374937 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0366095 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0360518 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.035931 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0356949 |
| PLTP | phospholipid transfer protein | -0.0355768 |
| SDCBP | syndecan binding protein (syntenin) | -0.0354549 |
| S100A2 | S100 calcium binding protein A2 | -0.0350079 |
| ARF1 | ADP-ribosylation factor 1 | -0.0349422 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0347657 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0347591 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0344642 |
| RPS21 | ribosomal protein S21 | -0.03444 |
| PGK1 | phosphoglycerate kinase 1 | -0.0343302 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.033992 |
| WASF2 | WAS protein family, member 2 | -0.0329669 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0329267 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0328226 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0325827 |
| FLNB | filamin B, beta | -0.0321078 |
| RPL11 | ribosomal protein L11 | -0.0318312 |
| ACTG1 | actin gamma 1 | -0.0316666 |
| RPL27A | ribosomal protein L27a | -0.0314998 |
| RPL19 | ribosomal protein L19 | -0.0310908 |
| RPS29 | ribosomal protein S29 | -0.0310675 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0310562 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0308361 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0306694 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0302786 |
| DENND1A | DENN/MADD domain containing 1A | -0.0300999 |
| TNS3 | tensin 3 | -0.0300874 |
| SEC24D | SEC24 family member D | -0.0300485 |
| CLIC4 | chloride intracellular channel 4 | -0.0299575 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.0299216 |
| EMP1 | epithelial membrane protein 1 | -0.0292226 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0291227 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0290925 |
| RUNX1 | runt-related transcription factor 1 | -0.0289855 |
| CAVIN1 | caveolae associated protein 1 | -0.0288242 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0284533 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0284216 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | -0.0282562 |
| KRT6A | keratin 6A, type II | -0.0281111 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0280547 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0275698 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0275455 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0273955 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0273438 |
| DGKH | diacylglycerol kinase, eta | -0.0271999 |
| ANXA1 | annexin A1 | -0.0270326 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0268543 |
| MECOM | MDS1 and EVI1 complex locus | -0.0267414 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0265284 |
| PLS3 | plastin 3 | -0.0260542 |
| PRSS23 | protease, serine, 23 | -0.0260131 |
| ZNF217 | zinc finger protein 217 | -0.0258276 |
| CRACDL | CRACD like | -0.0257886 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0253965 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0251357 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0250011 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0247364 |