| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sulfisoxazole perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Sulfisoxazole_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.146159 |
| EZR | ezrin | 0.0759944 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0757269 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0724036 |
| EMP1 | epithelial membrane protein 1 | 0.0690962 |
| RBM39 | RNA binding motif protein 39 | 0.0671168 |
| RPS6 | ribosomal protein S6 | 0.0606522 |
| ANXA1 | annexin A1 | 0.0561575 |
| ASPH | aspartate beta-hydroxylase | 0.0505483 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0476586 |
| DSPP | dentin sialophosphoprotein | 0.0456161 |
| PLEC | plectin | 0.0452017 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.0446033 |
| SMAD3 | SMAD family member 3 | 0.0443016 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.043783 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0434308 |
| PTMA | prothymosin, alpha | 0.0422853 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0409385 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.039613 |
| RPL35A | ribosomal protein L35a | 0.0389092 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0373049 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0371774 |
| NDRG1 | N-myc downstream regulated 1 | 0.0363756 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.035233 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0347527 |
| MYOF | myoferlin | 0.0338785 |
| DST | dystonin | 0.0333707 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0323908 |
| AREG | amphiregulin | 0.0320453 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0319194 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0318063 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0312279 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0305091 |
| RPS8 | ribosomal protein S8 | 0.0304693 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0302378 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0302195 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0297272 |
| AHNAK | AHNAK nucleoprotein | 0.0295971 |
| OGA | O-GlcNAcase | 0.029591 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0290347 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.028928 |
| SEPTIN9 | septin 9 | 0.0288043 |
| LMNA | lamin A/C | 0.0287369 |
| EFNA5 | ephrin-A5 | 0.0282912 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.027823 |
| FRMD5 | FERM domain containing 5 | 0.0276713 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0269898 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0269805 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0268736 |
| RPL26 | ribosomal protein L26 | 0.0259765 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0257522 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0255206 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0254489 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0253294 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0253018 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0252718 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0250366 |
| LAMB3 | laminin, beta 3 | 0.0249636 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0248119 |
| PRELID2 | PRELI domain containing 2 | 0.0247155 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0244649 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0243569 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0241919 |
| SQSTM1 | sequestosome 1 | 0.0240493 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0238603 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0237605 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0229754 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.022898 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0227755 |
| RPS19 | ribosomal protein S19 | 0.0225835 |
| RPL37A | ribosomal protein L37a | 0.0225753 |
| LCN2 | lipocalin 2 | 0.0224804 |
| EGFR | epidermal growth factor receptor | 0.0224317 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0222321 |
| FTL | ferritin, light polypeptide | 0.022209 |
| USP53 | ubiquitin specific peptidase 53 | 0.0219736 |
| RPL23 | ribosomal protein L23 | 0.0217359 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0215937 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0215037 |
| TXNRD1 | thioredoxin reductase 1 | 0.021237 |
| HMGB2 | high mobility group box 2 | 0.021102 |
| JMJD1C | jumonji domain containing 1C | 0.0210173 |
| SNX9 | sorting nexin 9 | 0.0207735 |
| RASEF | RAS and EF-hand domain containing | 0.0206674 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0206522 |
| HLA-A | major histocompatibility complex, class I, A | 0.0205304 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0200651 |
| PPL | periplakin | 0.0198221 |
| RPS29 | ribosomal protein S29 | 0.0198194 |
| SPAG9 | sperm associated antigen 9 | 0.0197556 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0195502 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0194976 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0191313 |
| FNIP1 | folliculin interacting protein 1 | 0.0188127 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0188007 |
| HKDC1 | hexokinase domain containing 1 | 0.018745 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0186904 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.0185577 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0185081 |
| TMC5 | transmembrane channel-like 5 | 0.0184319 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.209414 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.196639 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.108594 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0994998 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0882757 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0714601 |
| POTEF | POTE ankyrin domain family, member F | -0.068753 |
| MUC17 | mucin 17, cell surface associated | -0.0611727 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0567858 |
| CDK6 | cyclin-dependent kinase 6 | -0.0553438 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0521613 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0509825 |
| TNIK | TRAF2 and NCK interacting kinase | -0.0505752 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0499327 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0498712 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.049503 |
| ANXA2 | annexin A2 | -0.0438675 |
| TMEM123 | transmembrane protein 123 | -0.0423455 |
| INSIG1 | insulin induced gene 1 | -0.0417723 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0417195 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0410847 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0408745 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0402263 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0399071 |
| S100A6 | S100 calcium binding protein A6 | -0.0388111 |
| GPX2 | glutathione peroxidase 2 | -0.0383216 |
| LYZ | lysozyme | -0.0361174 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0359258 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.035006 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.034427 |
| YAP1 | Yes-associated protein 1 | -0.034316 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0343029 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0337432 |
| PRSS3 | protease, serine, 3 | -0.0331005 |
| HMGA1 | high mobility group AT-hook 1 | -0.0329384 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0327903 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0326204 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0323793 |
| RUNX1 | runt-related transcription factor 1 | -0.0323652 |
| TCF12 | transcription factor 12 | -0.0322233 |
| FAT1 | FAT atypical cadherin 1 | -0.0317756 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0314998 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0312967 |
| MCU | mitochondrial calcium uniporter | -0.0310131 |
| FASN | fatty acid synthase | -0.0305448 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0293071 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0286966 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0286944 |
| PLSCR1 | phospholipid scramblase 1 | -0.0285283 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | -0.0283201 |
| SULF2 | sulfatase 2 | -0.0278975 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0278412 |
| CCNL1 | cyclin L1 | -0.0274 |
| PKM | pyruvate kinase, muscle | -0.0271308 |
| ABHD2 | abhydrolase domain containing 2 | -0.0270925 |
| SH3RF1 | SH3 domain containing ring finger 1 | -0.0268064 |
| ARHGAP6 | Rho GTPase activating protein 6 | -0.0267321 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0263915 |
| B2M | beta-2-microglobulin | -0.0263803 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0263167 |
| VEGFA | vascular endothelial growth factor A | -0.0262061 |
| APOL6 | apolipoprotein L, 6 | -0.0261543 |
| EHBP1 | EH domain binding protein 1 | -0.0259045 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0257296 |
| TAPBP | TAP binding protein (tapasin) | -0.0251215 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | -0.0247967 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0247567 |
| MECOM | MDS1 and EVI1 complex locus | -0.0246249 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0245841 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0244278 |
| ETNK1 | ethanolamine kinase 1 | -0.0243463 |
| CLDN7 | claudin 7 | -0.0242438 |
| IRF1 | interferon regulatory factor 1 | -0.0241717 |
| EGR1 | early growth response 1 | -0.024081 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0239848 |
| MSMO1 | methylsterol monooxygenase 1 | -0.0238473 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0236499 |
| MUC1 | mucin 1, cell surface associated | -0.0233631 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.023013 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.022997 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0228791 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.0225676 |
| DSTN | destrin (actin depolymerizing factor) | -0.0224993 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.022487 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.022354 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0223453 |
| TTYH3 | tweety family member 3 | -0.022329 |
| TPM4 | tropomyosin 4 | -0.0217979 |
| PKP4 | plakophilin 4 | -0.0217963 |
| MX1 | MX dynamin-like GTPase 1 | -0.0215281 |
| CTSE | cathepsin E | -0.0213465 |
| HYOU1 | hypoxia up-regulated 1 | -0.0213015 |
| TFRC | transferrin receptor | -0.0210411 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0210119 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | -0.0210046 |
| WWC1 | WW and C2 domain containing 1 | -0.0207169 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | -0.0206581 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | -0.020321 |
| LDHA | lactate dehydrogenase A | -0.0202843 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0201816 |