| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sulfisoxazole perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sulfisoxazole_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FAT1 | FAT atypical cadherin 1 | 0.0907338 |
| LMO7 | LIM domain 7 | 0.0859749 |
| DSPP | dentin sialophosphoprotein | 0.085717 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0825557 |
| RPL4 | ribosomal protein L4 | 0.0756541 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0756101 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0754589 |
| RPS12 | ribosomal protein S12 | 0.0739622 |
| EZR | ezrin | 0.0675136 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0650918 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0608269 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0584073 |
| MYO1E | myosin IE | 0.0582531 |
| RPS2 | ribosomal protein S2 | 0.0563108 |
| VEGFA | vascular endothelial growth factor A | 0.0515301 |
| MUC13 | mucin 13, cell surface associated | 0.0515255 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.0497366 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0490979 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0468622 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0467106 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0465187 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0447394 |
| AREG | amphiregulin | 0.0441756 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0440343 |
| JUN | jun proto-oncogene | 0.0435403 |
| ENO1 | enolase 1, (alpha) | 0.0434019 |
| RPL3 | ribosomal protein L3 | 0.0407509 |
| ITGB4 | integrin, beta 4 | 0.040687 |
| RPS3 | ribosomal protein S3 | 0.0391047 |
| UBC | ubiquitin C | 0.0386146 |
| PRRC2C | proline-rich coiled-coil 2C | 0.038112 |
| RPS18 | ribosomal protein S18 | 0.0373137 |
| PLEC | plectin | 0.0368207 |
| ONECUT3 | one cut homeobox 3 | 0.0351201 |
| ASPH | aspartate beta-hydroxylase | 0.0344881 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0340819 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0339299 |
| TPM3 | tropomyosin 3 | 0.0330092 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0328715 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0305957 |
| CALR | calreticulin | 0.0296018 |
| PKM | pyruvate kinase, muscle | 0.0287246 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0279221 |
| CLCN3 | chloride channel, voltage-sensitive 3 | 0.027767 |
| SLK | STE20-like kinase | 0.0275004 |
| MED13 | mediator complex subunit 13 | 0.0271444 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0270983 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0270403 |
| LAMA4 | laminin, alpha 4 | 0.0268841 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0267703 |
| BMP4 | bone morphogenetic protein 4 | 0.0264319 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0262013 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0256883 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0254878 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0253765 |
| RPL26 | ribosomal protein L26 | 0.0246935 |
| RPS27A | ribosomal protein S27a | 0.0244875 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.0244712 |
| RPS15A | ribosomal protein S15a | 0.0244192 |
| GOLGB1 | golgin B1 | 0.0244177 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0243174 |
| PRSS3 | protease, serine, 3 | 0.0242009 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0241029 |
| EMP1 | epithelial membrane protein 1 | 0.0228438 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0227948 |
| ABHD2 | abhydrolase domain containing 2 | 0.0225641 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0222568 |
| CLDN4 | claudin 4 | 0.0216864 |
| B2M | beta-2-microglobulin | 0.0216494 |
| DHFR | dihydrofolate reductase | 0.0216092 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0215633 |
| TLN1 | talin 1 | 0.0212334 |
| FLNB | filamin B, beta | 0.0210319 |
| PIGR | polymeric immunoglobulin receptor | 0.020944 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0205603 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0204554 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0203932 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.020254 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.020179 |
| TMF1 | TATA element modulatory factor 1 | 0.0199917 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0198606 |
| PRRC2B | proline-rich coiled-coil 2B | 0.019857 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0194496 |
| APP | amyloid beta (A4) precursor protein | 0.0194122 |
| LIPH | lipase, member H | 0.0193798 |
| TMEM45B | transmembrane protein 45B | 0.0193022 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0192627 |
| HLA-A | major histocompatibility complex, class I, A | 0.0192413 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0190948 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0189264 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0188955 |
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | 0.0188673 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0188228 |
| LAMC2 | laminin, gamma 2 | 0.0185808 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0184725 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0182825 |
| SET | SET nuclear proto-oncogene | 0.0181303 |
| DUSP4 | dual specificity phosphatase 4 | 0.0180334 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0179622 |
| SEPTIN9 | septin 9 | 0.0179601 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.333078 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.242595 |
| NPSR1 | neuropeptide S receptor 1 | -0.150128 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.108694 |
| GPHN | gephyrin | -0.100048 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0823932 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0745586 |
| TMSB10 | thymosin beta 10 | -0.0726442 |
| RPLP0 | ribosomal protein, large, P0 | -0.0687539 |
| RPS24 | ribosomal protein S24 | -0.0648174 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.063752 |
| RPS23 | ribosomal protein S23 | -0.062728 |
| RPL35A | ribosomal protein L35a | -0.0626112 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0585517 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0538769 |
| RPS25 | ribosomal protein S25 | -0.0532544 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0505572 |
| AGR2 | anterior gradient 2 | -0.0504066 |
| PTMA | prothymosin, alpha | -0.0500438 |
| HMGA1 | high mobility group AT-hook 1 | -0.0495926 |
| RPL8 | ribosomal protein L8 | -0.048993 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0468372 |
| SETD5 | SET domain containing 5 | -0.0456394 |
| RPL12 | ribosomal protein L12 | -0.0449549 |
| RPL34 | ribosomal protein L34 | -0.0447666 |
| ANXA2 | annexin A2 | -0.0437512 |
| RPS21 | ribosomal protein S21 | -0.0432488 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0432298 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.042705 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0413681 |
| S100A6 | S100 calcium binding protein A6 | -0.0413118 |
| RPS6 | ribosomal protein S6 | -0.0411085 |
| RPS19 | ribosomal protein S19 | -0.0410059 |
| RPLP1 | ribosomal protein, large, P1 | -0.0396814 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0396727 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0392646 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0390358 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0387587 |
| RPL27A | ribosomal protein L27a | -0.0386803 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0373764 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0371724 |
| RPL11 | ribosomal protein L11 | -0.0371484 |
| ACTG1 | actin gamma 1 | -0.0370416 |
| VCL | vinculin | -0.0365351 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0364649 |
| RPL7A | ribosomal protein L7a | -0.0357714 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0357243 |
| MSI2 | musashi RNA-binding protein 2 | -0.0356516 |
| TFRC | transferrin receptor | -0.0354187 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0351768 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0347599 |
| FAM13A | family with sequence similarity 13, member A | -0.033879 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0337432 |
| RPL38 | ribosomal protein L38 | -0.0335242 |
| RPL19 | ribosomal protein L19 | -0.0334252 |
| USP3 | ubiquitin specific peptidase 3 | -0.0330931 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0328884 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0328362 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0327384 |
| NFIA | nuclear factor I/A | -0.0326611 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.032588 |
| RPS16 | ribosomal protein S16 | -0.0323639 |
| RPLP2 | ribosomal protein, large, P2 | -0.0322663 |
| MED13L | mediator complex subunit 13-like | -0.0322579 |
| SBF2 | SET binding factor 2 | -0.0319641 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.031807 |
| DENND1A | DENN/MADD domain containing 1A | -0.0317564 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0314634 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0314231 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0313536 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.031285 |
| RPL32 | ribosomal protein L32 | -0.0311984 |
| S100A9 | S100 calcium binding protein A9 | -0.0311639 |
| FHIT | fragile histidine triad | -0.0309667 |
| INSIG1 | insulin induced gene 1 | -0.0307528 |
| DEK | DEK proto-oncogene | -0.0306437 |
| IER3 | immediate early response 3 | -0.0306378 |
| COG5 | component of oligomeric golgi complex 5 | -0.0305553 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0304872 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.0304407 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.030419 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0300926 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.030087 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0299997 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.029962 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0299464 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0298603 |
| TMEM123 | transmembrane protein 123 | -0.0295802 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0294081 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0292303 |
| FTL | ferritin, light polypeptide | -0.0292124 |
| SEC24D | SEC24 family member D | -0.0292042 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.029154 |
| MECOM | MDS1 and EVI1 complex locus | -0.0289149 |
| S100P | S100 calcium binding protein P | -0.0287789 |
| POTEF | POTE ankyrin domain family, member F | -0.0287661 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0286672 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.0285954 |
| MORF4L2 | mortality factor 4 like 2 | -0.0284972 |
| RPL7 | ribosomal protein L7 | -0.0282878 |
