| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sulfisoxazole perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Sulfisoxazole_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGR1 | early growth response 1 | 0.120573 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.108447 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0844206 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0802021 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.079018 |
| CES1 | carboxylesterase 1 | 0.0707889 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0704018 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0702033 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0671295 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0666059 |
| FAM13A | family with sequence similarity 13, member A | 0.0660753 |
| MT2A | metallothionein 2A | 0.0557777 |
| SLTM | SAFB-like, transcription modulator | 0.0548319 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0467981 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0464136 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0446974 |
| RBM39 | RNA binding motif protein 39 | 0.0438406 |
| RPS12 | ribosomal protein S12 | 0.0427885 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.042656 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0421101 |
| RPL4 | ribosomal protein L4 | 0.0417527 |
| SMAD3 | SMAD family member 3 | 0.0405791 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0405778 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0392563 |
| EFNA5 | ephrin-A5 | 0.0368408 |
| NDRG1 | N-myc downstream regulated 1 | 0.0362991 |
| STC1 | stanniocalcin 1 | 0.0360756 |
| YBX3 | Y box binding protein 3 | 0.0349674 |
| ZNF292 | zinc finger protein 292 | 0.0349349 |
| AREG | amphiregulin | 0.0348426 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0339724 |
| RPS6 | ribosomal protein S6 | 0.0334822 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0334634 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0327892 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0320624 |
| MYO1E | myosin IE | 0.0316599 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0316583 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0309866 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0308808 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0307786 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0306679 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0305935 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0301447 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.029978 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.029932 |
| RPS2 | ribosomal protein S2 | 0.0298325 |
| RAD51B | RAD51 paralog B | 0.0298048 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0296721 |
| JUN | jun proto-oncogene | 0.0291644 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.029015 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0288925 |
| EZR | ezrin | 0.0286476 |
| IRS2 | insulin receptor substrate 2 | 0.0286304 |
| SPAG9 | sperm associated antigen 9 | 0.0270956 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0265799 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0263311 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0263069 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0262936 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0260341 |
| JMJD1C | jumonji domain containing 1C | 0.0255757 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0253434 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0251621 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0251302 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0248171 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0244699 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.02408 |
| ATP11A | ATPase, class VI, type 11A | 0.0240728 |
| ANGPTL4 | angiopoietin-like 4 | 0.0239715 |
| HMGA2 | high mobility group AT-hook 2 | 0.0239602 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0239342 |
| GOLGA4 | golgin A4 | 0.0238776 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0237964 |
| MSN | moesin | 0.0237243 |
| BMP6 | bone morphogenetic protein 6 | 0.0235872 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0235805 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0234516 |
| MCL1 | myeloid cell leukemia 1 | 0.0233145 |
| FRY | furry homolog (Drosophila) | 0.0230974 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0228957 |
| SIK3 | SIK family kinase 3 | 0.0228507 |
| RPLP1 | ribosomal protein, large, P1 | 0.0227144 |
| RPL37A | ribosomal protein L37a | 0.0225919 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0225622 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0222842 |
| TMEM45B | transmembrane protein 45B | 0.0222641 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0221677 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0219496 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0218741 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0218359 |
| PER2 | period circadian clock 2 | 0.021725 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0216308 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0215357 |
| ITSN2 | intersectin 2 | 0.0213138 |
| ITGB5 | integrin, beta 5 | 0.0212768 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | 0.0212675 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0210729 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0210338 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0210102 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0209698 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0209529 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.259655 |
| TXNRD1 | thioredoxin reductase 1 | -0.220284 |
| ASPH | aspartate beta-hydroxylase | -0.183402 |
| EGFR | epidermal growth factor receptor | -0.174342 |
| UBC | ubiquitin C | -0.0983021 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0855439 |
| LDHA | lactate dehydrogenase A | -0.0785455 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0779224 |
| ACTG1 | actin gamma 1 | -0.0767992 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0738398 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0735401 |
| AHNAK | AHNAK nucleoprotein | -0.0683272 |
| HDLBP | high density lipoprotein binding protein | -0.0672333 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0634544 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0625871 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.056478 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0541998 |
| CANX | calnexin | -0.053263 |
| SCEL | sciellin | -0.0525746 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0524134 |
| FTL | ferritin, light polypeptide | -0.0518984 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0511282 |
| NABP1 | nucleic acid binding protein 1 | -0.0432799 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0426196 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0415677 |
| ANXA2 | annexin A2 | -0.0407269 |
| INTS6 | integrator complex subunit 6 | -0.0404132 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0372267 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.036936 |
| LRP12 | low density lipoprotein receptor-related protein 12 | -0.036599 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0363952 |
| MKI67 | marker of proliferation Ki-67 | -0.0363492 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.036266 |
| KRT8 | keratin 8, type II | -0.0361315 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0357216 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0353307 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0351075 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0346603 |
| WASF2 | WAS protein family, member 2 | -0.0338466 |
| MYOF | myoferlin | -0.0337142 |
| KRT7 | keratin 7, type II | -0.0331952 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0319822 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0311222 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0309203 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0306613 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0304988 |
| PCBP2 | poly(rC) binding protein 2 | -0.0304981 |
| RAB10 | RAB10, member RAS oncogene family | -0.0303712 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0302909 |
| TNS3 | tensin 3 | -0.030272 |
| RPS27A | ribosomal protein S27a | -0.0302488 |
| MCU | mitochondrial calcium uniporter | -0.0298877 |
| MGST1 | microsomal glutathione S-transferase 1 | -0.0291285 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0289237 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0285049 |
| ECT2 | epithelial cell transforming 2 | -0.0282756 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0275115 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0272429 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0269216 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0267671 |
| TES | testin LIM domain protein | -0.0267362 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0265076 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.026422 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.026078 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0257208 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0255586 |
| GM2A | GM2 ganglioside activator | -0.0255512 |
| TKT | transketolase | -0.0254037 |
| FRYL | FRY-like | -0.0252764 |
| PGK1 | phosphoglycerate kinase 1 | -0.0251635 |
| WDR45B | WD repeat domain 45B | -0.0251241 |
| PERP | PERP, TP53 apoptosis effector | -0.0249387 |
| H1-0 | H1.0 linker histone | -0.0247956 |
| SEPTIN2 | septin 2 | -0.0243922 |
| MARF1 | meiosis regulator and mRNA stability factor 1 | -0.0242888 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0240895 |
| HYOU1 | hypoxia up-regulated 1 | -0.0240609 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0240042 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0239025 |
| RPS25 | ribosomal protein S25 | -0.0237785 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0232957 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0232814 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0232651 |
| OSMR | oncostatin M receptor | -0.0232642 |
| AEBP2 | AE binding protein 2 | -0.0232452 |
| TAOK1 | TAO kinase 1 | -0.023164 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0229761 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0229728 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0228929 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.022834 |
| NCOA2 | nuclear receptor coactivator 2 | -0.0228017 |
| TMEM165 | transmembrane protein 165 | -0.0227986 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0227281 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0226597 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0225706 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0224756 |
| CCND1 | cyclin D1 | -0.0223336 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0222436 |
| CCNI | cyclin I | -0.0221788 |
| NDE1 | nudE neurodevelopment protein 1 | -0.0221598 |
