| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sulfisoxazole perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Sulfisoxazole_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.262561 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.128159 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.10761 |
| NAV2 | neuron navigator 2 | 0.0856204 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0783352 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0775172 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0757654 |
| LOX | lysyl oxidase | 0.0734363 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0700021 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0680375 |
| ANGPTL4 | angiopoietin-like 4 | 0.0639688 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0638391 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0623852 |
| SMAD3 | SMAD family member 3 | 0.0605747 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0599802 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0597645 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0569502 |
| TGM2 | transglutaminase 2 | 0.0546723 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0541108 |
| MYO10 | myosin X | 0.051598 |
| NTN4 | netrin 4 | 0.0512575 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0511596 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0511243 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0508063 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0506326 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0505324 |
| RPL4 | ribosomal protein L4 | 0.0499695 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0494354 |
| CD44 | CD44 molecule (Indian blood group) | 0.0492555 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0467785 |
| VMP1 | vacuole membrane protein 1 | 0.0448669 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.044687 |
| STK38L | serine/threonine kinase 38 like | 0.0424362 |
| RPS12 | ribosomal protein S12 | 0.0419863 |
| KSR1 | kinase suppressor of ras 1 | 0.0412518 |
| LOXL2 | lysyl oxidase-like 2 | 0.0407417 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0393185 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0382396 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0376822 |
| SEPTIN9 | septin 9 | 0.0369147 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0368151 |
| RPS6 | ribosomal protein S6 | 0.0367828 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0367264 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0366242 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0356761 |
| DST | dystonin | 0.0350603 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0347603 |
| RHCG | Rh family, C glycoprotein | 0.0330791 |
| RBM39 | RNA binding motif protein 39 | 0.0326136 |
| RPS17 | ribosomal protein S17 | 0.0323678 |
| OPTN | optineurin | 0.0322729 |
| FLNB | filamin B, beta | 0.0321592 |
| SQSTM1 | sequestosome 1 | 0.0317791 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.03163 |
| CAPRIN2 | caprin family member 2 | 0.0309752 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0308349 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0304867 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0303211 |
| WLS | wntless Wnt ligand secretion mediator | 0.0298246 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0290526 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0288992 |
| ENO1 | enolase 1, (alpha) | 0.0285082 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0275929 |
| ECE1 | endothelin converting enzyme 1 | 0.0270281 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.026742 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0265445 |
| RARB | retinoic acid receptor, beta | 0.0264849 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0264044 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.0261931 |
| MLPH | melanophilin | 0.0259521 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0254564 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0254259 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0253962 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0251968 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0250768 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0247233 |
| JUN | jun proto-oncogene | 0.0245714 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0240603 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0237709 |
| TOP6BL | TOP6B like initiator of meiotic double strand breaks | 0.0237333 |
| PALLD | palladin, cytoskeletal associated protein | 0.0235399 |
| RPS18 | ribosomal protein S18 | 0.0233947 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.023381 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0233496 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0230982 |
| USP53 | ubiquitin specific peptidase 53 | 0.0230326 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.023013 |
| PLEC | plectin | 0.0230106 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0229878 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.022758 |
| ZNF638 | zinc finger protein 638 | 0.0225944 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0224285 |
| FBXO32 | F-box protein 32 | 0.0224094 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.022375 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.022322 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0223172 |
| RPL5 | ribosomal protein L5 | 0.0221326 |
| INTS6 | integrator complex subunit 6 | 0.0221146 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0218659 |
| TGFB2 | transforming growth factor, beta 2 | 0.0216807 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.168787 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.167601 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.153644 |
| FN1 | fibronectin 1 | -0.119925 |
| CDH13 | cadherin 13 | -0.115539 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.112843 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.112012 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0895223 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0852799 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0783 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0768016 |
| TMSB10 | thymosin beta 10 | -0.0736633 |
| GPC6 | glypican 6 | -0.0727484 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0696546 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0659778 |
| PCBP2 | poly(rC) binding protein 2 | -0.0655273 |
| USP34 | ubiquitin specific peptidase 34 | -0.0608017 |
| NRG1 | neuregulin 1 | -0.0606658 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0605922 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0603922 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0584891 |
| OSMR | oncostatin M receptor | -0.0558963 |
| NCOA7 | nuclear receptor coactivator 7 | -0.054967 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0511578 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0510303 |
| POTEF | POTE ankyrin domain family, member F | -0.0497051 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0483298 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0482701 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0476855 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0473655 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0461888 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0446473 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0444171 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0434914 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0429985 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0417564 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0416081 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0407657 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0398201 |
| TMEM263 | transmembrane protein 263 | -0.0396526 |
| TMEM165 | transmembrane protein 165 | -0.0392889 |
| MECOM | MDS1 and EVI1 complex locus | -0.0392822 |
| HMGA1 | high mobility group AT-hook 1 | -0.0391348 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0388549 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0388034 |
| HMGA2 | high mobility group AT-hook 2 | -0.0384705 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0379121 |
| PARD3 | par-3 family cell polarity regulator | -0.037575 |
| CCDC91 | coiled-coil domain containing 91 | -0.0374328 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0372489 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0368116 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0364847 |
| NAV3 | neuron navigator 3 | -0.0359352 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0356094 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0356047 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.035461 |
| ATG7 | autophagy related 7 | -0.0348164 |
| MX2 | MX dynamin-like GTPase 2 | -0.0344949 |
| FTL | ferritin, light polypeptide | -0.0341256 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0340948 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0334728 |
| MTSS1 | metastasis suppressor 1 | -0.033091 |
| NDRG1 | N-myc downstream regulated 1 | -0.0329838 |
| ZNF804A | zinc finger protein 804A | -0.0323677 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0319054 |
| LDHA | lactate dehydrogenase A | -0.0317932 |
| PCNX1 | pecanex 1 | -0.0316789 |
| VRK2 | vaccinia related kinase 2 | -0.0316632 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0316447 |
| SBF2 | SET binding factor 2 | -0.0315725 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0315432 |
| ABCA6 | ATP-binding cassette, sub-family A (ABC1), member 6 | -0.0314808 |
| COL12A1 | collagen, type XII, alpha 1 | -0.0310262 |
| STC1 | stanniocalcin 1 | -0.0309587 |
| WDR45B | WD repeat domain 45B | -0.0302397 |
| CDK14 | cyclin-dependent kinase 14 | -0.0301212 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0294864 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0294431 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0291962 |
| RAD51B | RAD51 paralog B | -0.0291476 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0289852 |
| DIAPH2 | diaphanous-related formin 2 | -0.0289706 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0286721 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0285076 |
| NF1 | neurofibromin 1 | -0.028391 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0283481 |
| CFAP20DC | CFAP20 domain containing | -0.0283054 |
| MORF4L2 | mortality factor 4 like 2 | -0.0280298 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0279833 |
| UBC | ubiquitin C | -0.0278961 |
| OXR1 | oxidation resistance 1 | -0.0273202 |
| IER3 | immediate early response 3 | -0.0272864 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0272045 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0268509 |
| CDCP1 | CUB domain containing protein 1 | -0.026791 |
| CCNI | cyclin I | -0.025917 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0257513 |
| FBN1 | fibrillin 1 | -0.0257482 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0256875 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0256761 |
