| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sulfisoxazole perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Sulfisoxazole_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.211521 |
| GRAMD1B | GRAM domain containing 1B | 0.135269 |
| MT2A | metallothionein 2A | 0.109343 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0861785 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0799755 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0789164 |
| RPL4 | ribosomal protein L4 | 0.0631469 |
| FAM107B | family with sequence similarity 107, member B | 0.063083 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0577425 |
| RBM39 | RNA binding motif protein 39 | 0.0573172 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0570157 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0530367 |
| WWOX | WW domain containing oxidoreductase | 0.0467388 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0460898 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0460763 |
| TPM3 | tropomyosin 3 | 0.0451527 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0437826 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0436806 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0420865 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.041594 |
| STC1 | stanniocalcin 1 | 0.0384455 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0372026 |
| DSE | dermatan sulfate epimerase | 0.0364354 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.03577 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0351303 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0338966 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0338543 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0320965 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0320832 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0320433 |
| RPS18 | ribosomal protein S18 | 0.0316165 |
| EZR | ezrin | 0.031226 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0311112 |
| HLA-A | major histocompatibility complex, class I, A | 0.0306991 |
| ANGPTL4 | angiopoietin-like 4 | 0.0306133 |
| ATXN1 | ataxin 1 | 0.0305301 |
| BMP6 | bone morphogenetic protein 6 | 0.0300692 |
| HLA-B | major histocompatibility complex, class I, B | 0.0298861 |
| INHBA | inhibin, beta A | 0.029445 |
| AXL | AXL receptor tyrosine kinase | 0.0285605 |
| NRG1 | neuregulin 1 | 0.0283834 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0278627 |
| NDRG1 | N-myc downstream regulated 1 | 0.0275869 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0275351 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0264516 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.026394 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0263922 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0261015 |
| EPAS1 | endothelial PAS domain protein 1 | 0.026053 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.025726 |
| DSPP | dentin sialophosphoprotein | 0.0255764 |
| GOLGB1 | golgin B1 | 0.0250604 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0247955 |
| PRELID2 | PRELI domain containing 2 | 0.024735 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0247209 |
| CD44 | CD44 molecule (Indian blood group) | 0.0242034 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0236937 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0236385 |
| USP53 | ubiquitin specific peptidase 53 | 0.0235591 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0232491 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0232275 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0230794 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0230543 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0229815 |
| MED13 | mediator complex subunit 13 | 0.0228638 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0227947 |
| TCIM | transcriptional and immune response regulator | 0.0223474 |
| ENO1 | enolase 1, (alpha) | 0.0221234 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0220633 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0218023 |
| OGA | O-GlcNAcase | 0.0214975 |
| MYO10 | myosin X | 0.0213319 |
| ITGA6 | integrin, alpha 6 | 0.0212144 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0210029 |
| TPR | translocated promoter region, nuclear basket protein | 0.0210004 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0208441 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0208416 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0207855 |
| CALR | calreticulin | 0.0207696 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0206967 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0205061 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0202878 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0200581 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0199249 |
| BMERB1 | bMERB domain containing 1 | 0.0195126 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0194123 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.019278 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0192284 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0191935 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0191271 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0190353 |
| B2M | beta-2-microglobulin | 0.0189941 |
| USP47 | ubiquitin specific peptidase 47 | 0.0189402 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0189225 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0185776 |
| NEMF | nuclear export mediator factor | 0.0183496 |
| TERF2IP | telomeric repeat binding factor 2, interacting protein | 0.018336 |
| RPS8 | ribosomal protein S8 | 0.018125 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0180631 |
| CHMP1B | charged multivesicular body protein 1B | 0.0180109 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.38503 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.273205 |
| TXNRD1 | thioredoxin reductase 1 | -0.108651 |
| IGF2 | insulin-like growth factor 2 | -0.0956529 |
| TMSB10 | thymosin beta 10 | -0.0811696 |
| FTL | ferritin, light polypeptide | -0.0762606 |
| ACTG1 | actin gamma 1 | -0.0749605 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0659156 |
| EGR1 | early growth response 1 | -0.0605912 |
| ERBIN | erbb2 interacting protein | -0.0605116 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0598337 |
| POTEF | POTE ankyrin domain family, member F | -0.0583266 |
| WDR43 | WD repeat domain 43 | -0.0576256 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0575795 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0519864 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0514862 |
| PTK2 | protein tyrosine kinase 2 | -0.0492033 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0483797 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0468005 |
| RASAL2 | RAS protein activator like 2 | -0.045617 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0453602 |
| AK1 | adenylate kinase 1 | -0.0449112 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.044288 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0422888 |
| RHOA | ras homolog family member A | -0.0421339 |
| LDHA | lactate dehydrogenase A | -0.0420817 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0398871 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0396615 |
| AHNAK | AHNAK nucleoprotein | -0.0394177 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0393456 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0390256 |
| CYRIB | CYFIP related Rac1 interactor B | -0.0389486 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0388514 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0375373 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.037507 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0369595 |
| EFNA5 | ephrin-A5 | -0.0369437 |
| PARD3 | par-3 family cell polarity regulator | -0.035275 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0349956 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0346524 |
| HDAC9 | histone deacetylase 9 | -0.0346119 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.034569 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.034368 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0342302 |
| BICC1 | BicC family RNA binding protein 1 | -0.0341383 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0341169 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0330377 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0318611 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0318397 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0317688 |
| IER3 | immediate early response 3 | -0.0315648 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0312008 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0311164 |
| WTAP | Wilms tumor 1 associated protein | -0.0307734 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.030765 |
| USP3 | ubiquitin specific peptidase 3 | -0.0306786 |
| PFN1 | profilin 1 | -0.0304598 |
| DENND4A | DENN/MADD domain containing 4A | -0.0303124 |
| KYNU | kynureninase | -0.0302338 |
| PKM | pyruvate kinase, muscle | -0.0301378 |
| FGB | fibrinogen beta chain | -0.0300432 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0294676 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0294562 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0291972 |
| NEGR1 | neuronal growth regulator 1 | -0.0290367 |
| TPD52 | tumor protein D52 | -0.0290197 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0287977 |
| UTRN | utrophin | -0.0282744 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0281569 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0277313 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0275625 |
| RHEB | Ras homolog enriched in brain | -0.0273031 |
| ECT2 | epithelial cell transforming 2 | -0.0272396 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0270158 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0270011 |
| NAV3 | neuron navigator 3 | -0.0269691 |
| CCNL1 | cyclin L1 | -0.0266233 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0264941 |
| BMPR1B | bone morphogenetic protein receptor, type IB | -0.0258948 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0258739 |
| FBXO11 | F-box protein 11 | -0.0256196 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0255023 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0253328 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.0251575 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0251055 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0248975 |
| TPM4 | tropomyosin 4 | -0.0246683 |
| CAVIN1 | caveolae associated protein 1 | -0.0245103 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0244036 |
| ANXA2 | annexin A2 | -0.0241909 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0239317 |
| RCC1 | regulator of chromosome condensation 1 | -0.0238256 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0234511 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0233159 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.023251 |
| TMED10 | transmembrane emp24-like trafficking protein 10 (yeast) | -0.0232156 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0231341 |
| GLG1 | golgi glycoprotein 1 | -0.0230285 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0229367 |
| HMGA1 | high mobility group AT-hook 1 | -0.0228875 |
