| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sulfisoxazole perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sulfisoxazole_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.089428 |
| PDE10A | phosphodiesterase 10A | 0.0887612 |
| IGF2 | insulin-like growth factor 2 | 0.0846542 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0799701 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0701761 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0689158 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0682892 |
| GPHN | gephyrin | 0.0651765 |
| RAD51B | RAD51 paralog B | 0.0638753 |
| KRT17 | keratin 17, type I | 0.0637672 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0635511 |
| RPL26 | ribosomal protein L26 | 0.0624482 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0590963 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0572774 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0572483 |
| EZR | ezrin | 0.0571989 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0570693 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0557936 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0536473 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0527862 |
| RBM25 | RNA binding motif protein 25 | 0.0522704 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0515662 |
| HMGA2 | high mobility group AT-hook 2 | 0.050455 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.050003 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0498136 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0479965 |
| DTNA | dystrobrevin, alpha | 0.0475894 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0473561 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0472421 |
| RBM15 | RNA binding motif protein 15 | 0.0463591 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.046279 |
| IRS2 | insulin receptor substrate 2 | 0.0462635 |
| ENO1 | enolase 1, (alpha) | 0.0461191 |
| RPL4 | ribosomal protein L4 | 0.0459837 |
| RPS3 | ribosomal protein S3 | 0.0457257 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0456811 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0453853 |
| JMJD1C | jumonji domain containing 1C | 0.0450865 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0441855 |
| LAMC2 | laminin, gamma 2 | 0.0433394 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0429382 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0422508 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0410619 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0406254 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0406034 |
| RPS27A | ribosomal protein S27a | 0.0399263 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0396585 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0396261 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0393665 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0391934 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0391074 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0389422 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | 0.0379882 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0378088 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0372457 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0372371 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0369068 |
| ANKRD11 | ankyrin repeat domain 11 | 0.036758 |
| RPS17 | ribosomal protein S17 | 0.0366096 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0363865 |
| RBM39 | RNA binding motif protein 39 | 0.0363339 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0361823 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0360666 |
| CERS6 | ceramide synthase 6 | 0.0356694 |
| FMNL2 | formin-like 2 | 0.035591 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0352256 |
| ZFHX3 | zinc finger homeobox 3 | 0.035077 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0348498 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0348174 |
| STC1 | stanniocalcin 1 | 0.0347357 |
| RPL31 | ribosomal protein L31 | 0.0346128 |
| KIF5B | kinesin family member 5B | 0.0345361 |
| QKI | QKI, KH domain containing, RNA binding | 0.0344168 |
| USP36 | ubiquitin specific peptidase 36 | 0.0341216 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0338068 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0337947 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0336796 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0332355 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0327165 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.032621 |
| UBE2D1 | ubiquitin-conjugating enzyme E2D 1 | 0.0325646 |
| RPL12 | ribosomal protein L12 | 0.0325377 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0324822 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0321203 |
| PRKCE | protein kinase C, epsilon | 0.031932 |
| HLA-A | major histocompatibility complex, class I, A | 0.0318051 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0316553 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0315486 |
| CDK6 | cyclin-dependent kinase 6 | 0.0315067 |
| RPL37A | ribosomal protein L37a | 0.0314214 |
| RPS24 | ribosomal protein S24 | 0.0313565 |
| CDH13 | cadherin 13 | 0.0312575 |
| GOLGA4 | golgin A4 | 0.0309124 |
| GPATCH8 | G patch domain containing 8 | 0.0305664 |
| FHIT | fragile histidine triad | 0.0305326 |
| POU2F1 | POU class 2 homeobox 1 | 0.030494 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0302409 |
| LMO7 | LIM domain 7 | 0.0301799 |
| INHBA | inhibin, beta A | 0.0299394 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0298613 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.177733 |
| MYO1E | myosin IE | -0.158314 |
| GRB10 | growth factor receptor-bound protein 10 | -0.151694 |
| MUC16 | mucin 16, cell surface associated | -0.107332 |
| FTL | ferritin, light polypeptide | -0.0979082 |
| AHNAK | AHNAK nucleoprotein | -0.0951491 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.087181 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0867933 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0856675 |
| VIM | vimentin | -0.082538 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0822458 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0795057 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0793837 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0789114 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.077876 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0768511 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0746579 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0706514 |
| ATOSA | atos homolog A | -0.0695124 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0672089 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0661279 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0657092 |
| ANXA2 | annexin A2 | -0.0655024 |
| SRPK2 | SRSF protein kinase 2 | -0.0649138 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0646479 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0628961 |
| MXD1 | MAX dimerization protein 1 | -0.0620597 |
| NBEAL1 | neurobeachin-like 1 | -0.059963 |
| ASPH | aspartate beta-hydroxylase | -0.0589285 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0587889 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0582371 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0562463 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.056142 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0550864 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0529072 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0523468 |
| ACTG1 | actin gamma 1 | -0.0522034 |
| S100A10 | S100 calcium binding protein A10 | -0.051774 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0513141 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0502616 |
| NDRG1 | N-myc downstream regulated 1 | -0.0495366 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0479363 |
| ANXA1 | annexin A1 | -0.0477939 |
| LDHA | lactate dehydrogenase A | -0.0474796 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0473399 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0468984 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0468972 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0466613 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0464728 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0462738 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0461685 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0451711 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0449394 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0447543 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0445715 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0442132 |
| NHSL1 | NHS-like 1 | -0.0438974 |
| RPLP0 | ribosomal protein, large, P0 | -0.0430863 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0427259 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.042035 |
| TUFT1 | tuftelin 1 | -0.0419235 |
| TAOK3 | TAO kinase 3 | -0.0418725 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0418334 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.041477 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | -0.0404111 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0403729 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0401085 |
| MYO5B | myosin VB | -0.040104 |
| WASL | Wiskott-Aldrich syndrome-like | -0.0401005 |
| RBM47 | RNA binding motif protein 47 | -0.0399711 |
| NEK7 | NIMA-related kinase 7 | -0.039651 |
| BPTF | bromodomain PHD finger transcription factor | -0.0393486 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0389491 |
| HOMER1 | homer scaffolding protein 1 | -0.0383919 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0377495 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.037721 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0376683 |
| CMIP | c-Maf inducing protein | -0.0370143 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0367967 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0363899 |
| COL6A3 | collagen, type VI, alpha 3 | -0.035712 |
| MATR3 | matrin 3 | -0.0356345 |
| ZNF609 | zinc finger protein 609 | -0.0354977 |
| TMEM123 | transmembrane protein 123 | -0.035461 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0353263 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0353147 |
| PARD3 | par-3 family cell polarity regulator | -0.0346272 |
| INTS6 | integrator complex subunit 6 | -0.034596 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0344161 |
| SFTPA2 | surfactant protein A2 | -0.0342588 |
| OXR1 | oxidation resistance 1 | -0.0340442 |
| SPAG9 | sperm associated antigen 9 | -0.0331799 |
| PRKCSH | protein kinase C substrate 80K-H | -0.0330551 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0327073 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0323851 |
| WASF2 | WAS protein family, member 2 | -0.0321907 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0321713 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.0321199 |
| UBAP1 | ubiquitin associated protein 1 | -0.0316269 |
| RAB8B | RAB8B, member RAS oncogene family | -0.0314746 |
