| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sulfisoxazole perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Sulfisoxazole_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.288291 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0911918 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0573733 |
| KRT18 | keratin 18, type I | 0.0572412 |
| RBM39 | RNA binding motif protein 39 | 0.052899 |
| FMNL2 | formin-like 2 | 0.0517845 |
| YBX3 | Y box binding protein 3 | 0.0498418 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0475043 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.047169 |
| RPS4X | ribosomal protein S4, X-linked | 0.0428677 |
| PRELID2 | PRELI domain containing 2 | 0.0416826 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0409982 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0397888 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0395005 |
| VMP1 | vacuole membrane protein 1 | 0.0392873 |
| HMGA2 | high mobility group AT-hook 2 | 0.0385727 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0375226 |
| WWOX | WW domain containing oxidoreductase | 0.0370409 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0360759 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.03518 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0350879 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0340594 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0333672 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.031476 |
| INTS6 | integrator complex subunit 6 | 0.0304891 |
| TLN1 | talin 1 | 0.0304724 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0304683 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0300687 |
| PDE10A | phosphodiesterase 10A | 0.0287985 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0282456 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0278609 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0275589 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0275433 |
| TPM2 | tropomyosin 2 (beta) | 0.027523 |
| SMAD3 | SMAD family member 3 | 0.0274765 |
| VCL | vinculin | 0.0272906 |
| KLF6 | Kruppel-like factor 6 | 0.0272416 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.026908 |
| RPL4 | ribosomal protein L4 | 0.0266955 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0266832 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0265745 |
| OSMR | oncostatin M receptor | 0.0248999 |
| ATP11A | ATPase, class VI, type 11A | 0.0246952 |
| HDAC4 | histone deacetylase 4 | 0.0246074 |
| AEBP2 | AE binding protein 2 | 0.0245263 |
| EGFR | epidermal growth factor receptor | 0.0241105 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.024017 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0239245 |
| DST | dystonin | 0.0238479 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0237388 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | 0.0234301 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0232438 |
| HOMER1 | homer scaffolding protein 1 | 0.0231759 |
| FHIT | fragile histidine triad | 0.0227892 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0223213 |
| EGR1 | early growth response 1 | 0.0217413 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0214121 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.021335 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | 0.0212488 |
| SVIL | supervillin | 0.021171 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0208874 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0207813 |
| ATXN1 | ataxin 1 | 0.0202963 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0198763 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0197902 |
| FUS | FUS RNA binding protein | 0.0188114 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0186953 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0186462 |
| INTS1 | integrator complex subunit 1 | 0.0185351 |
| RPL35 | ribosomal protein L35 | 0.0183001 |
| COPA | coatomer protein complex, subunit alpha | 0.0181066 |
| JUN | jun proto-oncogene | 0.0179329 |
| PER1 | period circadian clock 1 | 0.0177488 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0173781 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0173094 |
| CAPRIN2 | caprin family member 2 | 0.0165804 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0164424 |
| INTS3 | integrator complex subunit 3 | 0.0161548 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0161133 |
| NRG1 | neuregulin 1 | 0.016061 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0160038 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.015975 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.015891 |
| ATP13A3 | ATPase type 13A3 | 0.0158264 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0157666 |
| PLEC | plectin | 0.0157312 |
| CREBBP | CREB binding protein | 0.0156803 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0156673 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0155456 |
| TCIM | transcriptional and immune response regulator | 0.0155154 |
| FLNB | filamin B, beta | 0.0154324 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0153458 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0151456 |
| RPL18 | ribosomal protein L18 | 0.0150749 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0148052 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0146743 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0146199 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0143561 |
| H1-0 | H1.0 linker histone | 0.0143516 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0142561 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TFPI2 | tissue factor pathway inhibitor 2 | -0.267246 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.236355 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.105847 |
| TXNRD1 | thioredoxin reductase 1 | -0.100137 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0678489 |
| PTMA | prothymosin, alpha | -0.0670756 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0654826 |
| RTN4 | reticulon 4 | -0.0643016 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0619451 |
| CCND2 | cyclin D2 | -0.0612963 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0590553 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0554776 |
| PHIP | pleckstrin homology domain interacting protein | -0.0554759 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0552135 |
| MKI67 | marker of proliferation Ki-67 | -0.0546704 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0542256 |
| RPL38 | ribosomal protein L38 | -0.0516219 |
| XPO1 | exportin 1 | -0.0513972 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.05091 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0505607 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0499489 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.04986 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0494802 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0494466 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0477824 |
| CENPF | centromere protein F, 350/400kDa | -0.0448658 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0445434 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.044027 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0439576 |
| ACTG1 | actin gamma 1 | -0.0427762 |
| ZFR | zinc finger RNA binding protein | -0.042469 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0414248 |
| ADAR | adenosine deaminase, RNA-specific | -0.0406172 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0403456 |
| GOLGA4 | golgin A4 | -0.0400588 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0400297 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0399722 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0397008 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.039695 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0395415 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0393521 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0392029 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0390662 |
| RPS2 | ribosomal protein S2 | -0.0384319 |
| TAOK1 | TAO kinase 1 | -0.0377825 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.037764 |
| RPS29 | ribosomal protein S29 | -0.0375533 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0372808 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0372528 |
| GATAD2B | GATA zinc finger domain containing 2B | -0.0371156 |
| FBXO11 | F-box protein 11 | -0.0367369 |
| RPS15 | ribosomal protein S15 | -0.0363911 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0360723 |
| RPS8 | ribosomal protein S8 | -0.0358804 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0351984 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0347021 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0344423 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0340371 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0338329 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0335491 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0328973 |
| CLTC | clathrin, heavy chain (Hc) | -0.0328765 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0321472 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0318706 |
| BBX | bobby sox homolog (Drosophila) | -0.031659 |
| POTEF | POTE ankyrin domain family, member F | -0.0315216 |
| SRPK1 | SRSF protein kinase 1 | -0.031212 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0310993 |
| SEPTIN7 | septin 7 | -0.0310317 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0309012 |
| HLA-B | major histocompatibility complex, class I, B | -0.0308182 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0307913 |
| RPL37A | ribosomal protein L37a | -0.030539 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0303724 |
| DEK | DEK proto-oncogene | -0.0303092 |
| CAVIN1 | caveolae associated protein 1 | -0.0302578 |
| RECQL | RecQ helicase-like | -0.0301774 |
| TUBA1B | tubulin, alpha 1b | -0.030131 |
| LDHB | lactate dehydrogenase B | -0.0301259 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0299217 |
| RPS10 | ribosomal protein S10 | -0.029921 |
| PLCB4 | phospholipase C, beta 4 | -0.0299191 |
| RAB10 | RAB10, member RAS oncogene family | -0.0298553 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0290392 |
| MED13L | mediator complex subunit 13-like | -0.028827 |
| CCDC91 | coiled-coil domain containing 91 | -0.0287662 |
| ZNF292 | zinc finger protein 292 | -0.0287271 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0284785 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.028469 |
| PPME1 | protein phosphatase methylesterase 1 | -0.0284569 |
| GOLT1B | golgi transport 1B | -0.0283398 |
| RASA2 | RAS p21 protein activator 2 | -0.0280425 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0280063 |
| PCNX1 | pecanex 1 | -0.0275787 |
| H3-3B | H3.3 histone B | -0.0272441 |
| CTTN | cortactin | -0.0267217 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0265983 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | -0.0264932 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0263204 |
| KIF5B | kinesin family member 5B | -0.0262808 |
