| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sulfisoxazole perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sulfisoxazole_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DST | dystonin | 0.125364 |
| PDLIM5 | PDZ and LIM domain 5 | 0.107439 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0995114 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0985965 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0864734 |
| KYNU | kynureninase | 0.082953 |
| PDE10A | phosphodiesterase 10A | 0.0824863 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0670121 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0659702 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0654822 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0615449 |
| FMNL2 | formin-like 2 | 0.0613234 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.060927 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.059924 |
| VCL | vinculin | 0.0575349 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0560727 |
| FNDC3A | fibronectin type III domain containing 3A | 0.051904 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0512242 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0510063 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0490218 |
| GRAMD1B | GRAM domain containing 1B | 0.047858 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0469239 |
| RPL4 | ribosomal protein L4 | 0.0466509 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.046244 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0457233 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0456131 |
| ASPH | aspartate beta-hydroxylase | 0.0454974 |
| MYOF | myoferlin | 0.044417 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0443318 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0420876 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0412592 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0409001 |
| SMAD2 | SMAD family member 2 | 0.040236 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0397476 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0394437 |
| RBM39 | RNA binding motif protein 39 | 0.0393541 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0373226 |
| PCBP3 | poly(rC) binding protein 3 | 0.0368364 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0363471 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0359626 |
| AUTS2 | autism susceptibility candidate 2 | 0.0359486 |
| BMP6 | bone morphogenetic protein 6 | 0.0347586 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0335165 |
| RAD51B | RAD51 paralog B | 0.0331691 |
| INTS6 | integrator complex subunit 6 | 0.0330138 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0325791 |
| FNIP1 | folliculin interacting protein 1 | 0.0325621 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0324905 |
| INHBA | inhibin, beta A | 0.0317687 |
| GDA | guanine deaminase | 0.0316639 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0313062 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0305146 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0298454 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0297049 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0296644 |
| ZNF638 | zinc finger protein 638 | 0.0293892 |
| HDAC4 | histone deacetylase 4 | 0.0288527 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0286059 |
| NTN4 | netrin 4 | 0.0281126 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0276621 |
| CD109 | CD109 molecule | 0.0275827 |
| RPS18 | ribosomal protein S18 | 0.027393 |
| EZR | ezrin | 0.0266764 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0261653 |
| PRELID2 | PRELI domain containing 2 | 0.0254374 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0253834 |
| DNER | delta/notch-like EGF repeat containing | 0.024958 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.02451 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0241012 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0237896 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0237746 |
| CD44 | CD44 molecule (Indian blood group) | 0.0227323 |
| USP53 | ubiquitin specific peptidase 53 | 0.0224818 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0224734 |
| IRS2 | insulin receptor substrate 2 | 0.0218981 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0217853 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0216744 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.021611 |
| COL5A2 | collagen, type V, alpha 2 | 0.0213978 |
| MYO10 | myosin X | 0.0212914 |
| COL4A6 | collagen, type IV, alpha 6 | 0.0212431 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0208926 |
| RASAL2 | RAS protein activator like 2 | 0.0205055 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0204053 |
| ATXN1 | ataxin 1 | 0.0203592 |
| TUT7 | terminal uridylyl transferase 7 | 0.0202225 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0201036 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0200853 |
| CUL3 | cullin 3 | 0.0200125 |
| EXOC6B | exocyst complex component 6B | 0.0198327 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0195211 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0194085 |
| RPS15A | ribosomal protein S15a | 0.0193648 |
| ITPK1 | inositol-tetrakisphosphate 1-kinase | 0.0192839 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0192711 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 0.0190359 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0188864 |
| CTBP2 | C-terminal binding protein 2 | 0.0187675 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.018367 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0183315 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.311067 |
| FN1 | fibronectin 1 | -0.252863 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.106149 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.101891 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0914356 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0785646 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0772838 |
| VIM | vimentin | -0.0704143 |
| PTMA | prothymosin, alpha | -0.068882 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0595148 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0574758 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0532048 |
| RPL19 | ribosomal protein L19 | -0.0506863 |
| RPS23 | ribosomal protein S23 | -0.0503867 |
| FTL | ferritin, light polypeptide | -0.050102 |
| PGK1 | phosphoglycerate kinase 1 | -0.0493996 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0492862 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0478653 |
| LDHA | lactate dehydrogenase A | -0.0450159 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.044952 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0438757 |
| TBXT | T-box transcription factor T | -0.0424251 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0422449 |
| RPS29 | ribosomal protein S29 | -0.0408047 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | -0.0361493 |
| STC1 | stanniocalcin 1 | -0.0356528 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0355251 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0348924 |
| RPL31 | ribosomal protein L31 | -0.0345029 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0344268 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.0343295 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0335916 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0328827 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0328045 |
| RPS25 | ribosomal protein S25 | -0.0323119 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0319853 |
| TMX4 | thioredoxin-related transmembrane protein 4 | -0.0317778 |
| RPS8 | ribosomal protein S8 | -0.0316724 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0314857 |
| NDRG1 | N-myc downstream regulated 1 | -0.0314025 |
| HLA-B | major histocompatibility complex, class I, B | -0.0311813 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0310777 |
| CANX | calnexin | -0.0310608 |
| RPS13 | ribosomal protein S13 | -0.0309704 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0309659 |
| MFF | mitochondrial fission factor | -0.0305513 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0304204 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0304073 |
| KIAA0825 | KIAA0825 | -0.0288296 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0285592 |
| CDH13 | cadherin 13 | -0.0284439 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0283571 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | -0.02763 |
| RPL11 | ribosomal protein L11 | -0.0271997 |
| SRGN | serglycin | -0.027154 |
| RGS2 | regulator of G-protein signaling 2 | -0.0270294 |
| WDR45B | WD repeat domain 45B | -0.0267625 |
| RPL36A | ribosomal protein L36a | -0.0267137 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.026616 |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa | -0.0255885 |
| NCKAP5 | NCK-associated protein 5 | -0.025569 |
| MT2A | metallothionein 2A | -0.0252108 |
| SRPK2 | SRSF protein kinase 2 | -0.0245515 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0243302 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0241889 |
| B2M | beta-2-microglobulin | -0.023916 |
| RTN4 | reticulon 4 | -0.0234349 |
| RPL7A | ribosomal protein L7a | -0.0229424 |
| PTGR1 | prostaglandin reductase 1 | -0.0225514 |
| IER3 | immediate early response 3 | -0.0224043 |
| AHNAK | AHNAK nucleoprotein | -0.0219722 |
| ACTG1 | actin gamma 1 | -0.0217643 |
| S100A10 | S100 calcium binding protein A10 | -0.0217438 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | -0.0216955 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0214092 |
| FAM13A | family with sequence similarity 13, member A | -0.0213316 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0207495 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0203861 |
| RPL8 | ribosomal protein L8 | -0.0200786 |
| RPL37A | ribosomal protein L37a | -0.0199858 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.019698 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0196321 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0195002 |
| RPS16 | ribosomal protein S16 | -0.0194509 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0193262 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0193255 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0191356 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0191091 |
| RPL34 | ribosomal protein L34 | -0.0190704 |
| RPS24 | ribosomal protein S24 | -0.0189086 |
| RPS15 | ribosomal protein S15 | -0.0188646 |
| SCCPDH | saccharopine dehydrogenase (putative) | -0.0188465 |
| RPL27A | ribosomal protein L27a | -0.018672 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0185605 |
| RPS27A | ribosomal protein S27a | -0.0185448 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0185285 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0184844 |
| SFTPA2 | surfactant protein A2 | -0.0184652 |
| TBC1D19 | TBC1 domain family, member 19 | -0.0183381 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0182188 |
