| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sulfisoxazole perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sulfisoxazole_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.215212 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.159618 |
| RBM39 | RNA binding motif protein 39 | 0.133741 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.12309 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.11632 |
| PTK2 | protein tyrosine kinase 2 | 0.111322 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.111088 |
| MED13L | mediator complex subunit 13-like | 0.108115 |
| LAMB3 | laminin, beta 3 | 0.107713 |
| NLGN1 | neuroligin 1 | 0.100378 |
| NAV1 | neuron navigator 1 | 0.0995382 |
| TJP1 | tight junction protein 1 | 0.0968379 |
| STC1 | stanniocalcin 1 | 0.0959976 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0954048 |
| VMP1 | vacuole membrane protein 1 | 0.0933078 |
| ACTN4 | actinin, alpha 4 | 0.0925792 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0920799 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0916593 |
| TXNRD1 | thioredoxin reductase 1 | 0.0900235 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0893963 |
| CTBP2 | C-terminal binding protein 2 | 0.0862044 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0851882 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0811091 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0791066 |
| GPHN | gephyrin | 0.0778743 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0777182 |
| PDE10A | phosphodiesterase 10A | 0.0776009 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0773941 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0724988 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0719117 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0699223 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0654436 |
| SMYD3 | SET and MYND domain containing 3 | 0.0650388 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.064945 |
| HELZ | helicase with zinc finger | 0.0645185 |
| FLNB | filamin B, beta | 0.063298 |
| INHBA | inhibin, beta A | 0.0603507 |
| HDLBP | high density lipoprotein binding protein | 0.0563451 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0552261 |
| EGFR | epidermal growth factor receptor | 0.0541049 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0525393 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0520157 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0515021 |
| ATP13A3 | ATPase type 13A3 | 0.0490509 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0489665 |
| RAD51B | RAD51 paralog B | 0.0471636 |
| DST | dystonin | 0.0458326 |
| MATR3 | matrin 3 | 0.043992 |
| RBM25 | RNA binding motif protein 25 | 0.0430304 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0421647 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0419291 |
| MYO10 | myosin X | 0.040862 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0388991 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0377665 |
| EFNA5 | ephrin-A5 | 0.0373365 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0363972 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0326858 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0326664 |
| HMGA2 | high mobility group AT-hook 2 | 0.0325635 |
| MT2A | metallothionein 2A | 0.0323009 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.031935 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0313908 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0278332 |
| FRMD4A | FERM domain containing 4A | 0.0277454 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0271716 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.027062 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.026908 |
| AHNAK | AHNAK nucleoprotein | 0.0256836 |
| LMO7 | LIM domain 7 | 0.0252986 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0248633 |
| ACTG1 | actin gamma 1 | 0.0240068 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0221535 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0221261 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0218909 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0207842 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0207002 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0203872 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0200284 |
| CD109 | CD109 molecule | 0.0196925 |
| PRKCA | protein kinase C, alpha | 0.0196556 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0187096 |
| ZNF609 | zinc finger protein 609 | 0.0167849 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0164196 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0162116 |
| TNS3 | tensin 3 | 0.0158192 |
| SETD5 | SET domain containing 5 | 0.0127267 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0124601 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0122475 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0122284 |
| NRXN3 | neurexin 3 | 0.0122211 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0120972 |
| SBF2 | SET binding factor 2 | 0.011014 |
| PRELID2 | PRELI domain containing 2 | 0.0103621 |
| RTN4 | reticulon 4 | 0.00960799 |
| SPIDR | scaffolding protein involved in DNA repair | 0.00950566 |
| GNAS | GNAS complex locus | 0.00935921 |
| OSMR | oncostatin M receptor | 0.0093307 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.00929854 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.00905709 |
| YAP1 | Yes-associated protein 1 | 0.00838814 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.23271 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.185139 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.12851 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.12796 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.101534 |
| TMSB10 | thymosin beta 10 | -0.0988851 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0988172 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0978946 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0930969 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0929025 |
| RIGI | RNA sensor RIG-I | -0.0917327 |
| RPS6 | ribosomal protein S6 | -0.0910152 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0904152 |
| COL5A2 | collagen, type V, alpha 2 | -0.0874654 |
| VIM | vimentin | -0.0840924 |
| PGK1 | phosphoglycerate kinase 1 | -0.0810616 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0804448 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0794113 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0787781 |
| ASPH | aspartate beta-hydroxylase | -0.0753242 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0739674 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0738519 |
| JMJD1C | jumonji domain containing 1C | -0.0700374 |
| PTMA | prothymosin, alpha | -0.0698505 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0694983 |
| GOLGA4 | golgin A4 | -0.0674599 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0667361 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0665326 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0651304 |
| RPL35A | ribosomal protein L35a | -0.064795 |
| GPC6 | glypican 6 | -0.0635827 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0628983 |
| EXT1 | exostosin glycosyltransferase 1 | -0.062294 |
| ZNF292 | zinc finger protein 292 | -0.0608688 |
| SPAG9 | sperm associated antigen 9 | -0.0594786 |
| PKM | pyruvate kinase, muscle | -0.0592467 |
| MED13 | mediator complex subunit 13 | -0.0575726 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0568228 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0565861 |
| B2M | beta-2-microglobulin | -0.0544379 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0539098 |
| ANO6 | anoctamin 6 | -0.0527078 |
| IGF2 | insulin-like growth factor 2 | -0.0510607 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0510468 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0507353 |
| CAVIN1 | caveolae associated protein 1 | -0.0503522 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.049582 |
| TXNIP | thioredoxin interacting protein | -0.0475956 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0469824 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.045728 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0446607 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0445431 |
| CD44 | CD44 molecule (Indian blood group) | -0.0440045 |
| TMEM165 | transmembrane protein 165 | -0.0435265 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0412759 |
| RPLP1 | ribosomal protein, large, P1 | -0.0411048 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.040832 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0389847 |
| FTL | ferritin, light polypeptide | -0.037467 |
| USP34 | ubiquitin specific peptidase 34 | -0.0374003 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0367628 |
| OGA | O-GlcNAcase | -0.0363353 |
| CANX | calnexin | -0.0359392 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0357608 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0353425 |
| GLIS3 | GLIS family zinc finger 3 | -0.0349848 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0349525 |
| RPL37A | ribosomal protein L37a | -0.0346509 |
| RNF213 | ring finger protein 213 | -0.0345123 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0324598 |
| KIF5B | kinesin family member 5B | -0.0310255 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0304004 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0265353 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0264386 |
| CUX1 | cut-like homeobox 1 | -0.0245747 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0239317 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0236717 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0235575 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0233605 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0233043 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0224208 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0219446 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0209348 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0200763 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0195903 |
| RUNX1 | runt-related transcription factor 1 | -0.0195798 |
| CDH13 | cadherin 13 | -0.0189541 |
| RPL26 | ribosomal protein L26 | -0.0182413 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0174544 |
| PARD3 | par-3 family cell polarity regulator | -0.0166637 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0162333 |
| MYOF | myoferlin | -0.0122158 |
| NABP1 | nucleic acid binding protein 1 | -0.0117644 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0113559 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0102208 |
| CEP170 | centrosomal protein 170kDa | -0.0100929 |
| NDRG1 | N-myc downstream regulated 1 | -0.009895 |
| NAV2 | neuron navigator 2 | -0.00910177 |
| MORF4L2 | mortality factor 4 like 2 | -0.00893235 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.00833061 |
