| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sulfisoxazole perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sulfisoxazole_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0666373 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0558093 |
| RPL4 | ribosomal protein L4 | 0.038247 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0373783 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0372986 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0353856 |
| DHFR | dihydrofolate reductase | 0.0319057 |
| GOLGA4 | golgin A4 | 0.0314 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0300109 |
| GPC4 | glypican 4 | 0.0286429 |
| EXT1 | exostosin glycosyltransferase 1 | 0.028173 |
| RPS18 | ribosomal protein S18 | 0.0279095 |
| RBM25 | RNA binding motif protein 25 | 0.027389 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0261015 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0248936 |
| DENND4A | DENN/MADD domain containing 4A | 0.0245843 |
| FOXG1 | forkhead box G1 | 0.0242491 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0223689 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0222453 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.022147 |
| SPECC1L | sperm antigen with calponin homology and coiled-coil domains 1-like | 0.0220891 |
| SMYD3 | SET and MYND domain containing 3 | 0.022015 |
| NBEA | neurobeachin | 0.021993 |
| WWOX | WW domain containing oxidoreductase | 0.0219783 |
| ZNF608 | zinc finger protein 608 | 0.0219641 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0218605 |
| SATB2 | SATB homeobox 2 | 0.021391 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0213463 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0211441 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.020975 |
| RPS2 | ribosomal protein S2 | 0.020819 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0204738 |
| PLEC | plectin | 0.0202741 |
| LCA5 | Leber congenital amaurosis 5 | 0.0200184 |
| HDAC8 | histone deacetylase 8 | 0.0199721 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0198865 |
| FOXN3 | forkhead box N3 | 0.019827 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0197247 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0194432 |
| PCDH18 | protocadherin 18 | 0.0194398 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0193513 |
| ANK2 | ankyrin 2, neuronal | 0.0193353 |
| PER1 | period circadian clock 1 | 0.0192815 |
| ELAVL3 | ELAV like neuron-specific RNA binding protein 3 | 0.0185768 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0183176 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0181777 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0181626 |
| FOXP2 | forkhead box P2 | 0.0180154 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | 0.0178277 |
| INHBA | inhibin, beta A | 0.0177757 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0177431 |
| ASPH | aspartate beta-hydroxylase | 0.0176671 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0175917 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0175239 |
| ERP44 | endoplasmic reticulum protein 44 | 0.0172821 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0171862 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0171636 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0170377 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0169999 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0166848 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0165724 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0165437 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0165415 |
| SET | SET nuclear proto-oncogene | 0.0164011 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0163088 |
| MACROD2 | MACRO domain containing 2 | 0.0162608 |
| STC1 | stanniocalcin 1 | 0.0161805 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0160893 |
| NONO | non-POU domain containing, octamer-binding | 0.0160577 |
| DOT1L | DOT1-like histone H3K79 methyltransferase | 0.0160072 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0159698 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0159456 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0156901 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0156614 |
| H1-4 | H1.4 linker histone, cluster member | 0.0156561 |
| CDK6 | cyclin-dependent kinase 6 | 0.0156301 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0156119 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0155696 |
| SOCS5 | suppressor of cytokine signaling 5 | 0.0154936 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0154471 |
| SLC25A12 | solute carrier family 25 (aspartate/glutamate carrier), member 12 | 0.0154405 |
| NBR1 | neighbor of BRCA1 gene 1 | 0.0154144 |
| MEF2A | myocyte enhancer factor 2A | 0.0154127 |
| CCND1 | cyclin D1 | 0.0153668 |
| ATM | ATM serine/threonine kinase | 0.0153642 |
| RPL18 | ribosomal protein L18 | 0.015182 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0151738 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0151225 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0150511 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0150319 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0149733 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0148551 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0146421 |
| KLHL24 | kelch-like family member 24 | 0.0145561 |
| TBC1D22A | TBC1 domain family, member 22A | 0.014538 |
| REST | RE1-silencing transcription factor | 0.0145216 |
| FARS2 | phenylalanyl-tRNA synthetase 2, mitochondrial | 0.0145135 |
| NUBPL | nucleotide binding protein-like | 0.0144581 |
| FNIP1 | folliculin interacting protein 1 | 0.0144347 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0144217 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.204362 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.201928 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.149157 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.133373 |
| ANKRD33B | ankyrin repeat domain 33B | -0.105868 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0968056 |
| PEG10 | paternally expressed 10 | -0.0942484 |
| GPC3 | glypican 3 | -0.0911515 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0890025 |
| RPS16 | ribosomal protein S16 | -0.0869846 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0864054 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0863154 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0862808 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0827507 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0784978 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0775394 |
| ACTG1 | actin gamma 1 | -0.0774509 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0730389 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0725096 |
| PHIP | pleckstrin homology domain interacting protein | -0.0681413 |
| RPLP0 | ribosomal protein, large, P0 | -0.0641384 |
| GNAS | GNAS complex locus | -0.0633774 |
| POTEF | POTE ankyrin domain family, member F | -0.0607797 |
| SPAG9 | sperm associated antigen 9 | -0.0578453 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0572027 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0570173 |
| EMP1 | epithelial membrane protein 1 | -0.0569389 |
| ANXA2 | annexin A2 | -0.0560208 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0555612 |
| CALU | calumenin | -0.0552089 |
| FBXO11 | F-box protein 11 | -0.0545471 |
| RFPL4B | ret finger protein-like 4B | -0.0538005 |
| COL1A2 | collagen, type I, alpha 2 | -0.0533581 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.052968 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0528035 |
| ENAH | enabled homolog (Drosophila) | -0.0518174 |
| UBC | ubiquitin C | -0.0512228 |
| B2M | beta-2-microglobulin | -0.0506027 |
| TUBA1B | tubulin, alpha 1b | -0.050595 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0502716 |
| ZNF217 | zinc finger protein 217 | -0.0502059 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0489077 |
| RPL23 | ribosomal protein L23 | -0.0488503 |
| HMGA1 | high mobility group AT-hook 1 | -0.0485729 |
| TMSB4X | thymosin beta 4, X-linked | -0.0483815 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0482965 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0477707 |
| PFN1 | profilin 1 | -0.0474378 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0472339 |
| AHNAK | AHNAK nucleoprotein | -0.0460482 |
| PTMA | prothymosin, alpha | -0.0460302 |
| RPS6 | ribosomal protein S6 | -0.0460235 |
| CAVIN1 | caveolae associated protein 1 | -0.0459712 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0459166 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0458683 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.045746 |
| RTN4 | reticulon 4 | -0.0455331 |
| ADNP | activity-dependent neuroprotector homeobox | -0.044257 |
| CDC73 | cell division cycle 73 | -0.0441907 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0438636 |
| TPX2 | TPX2, microtubule-associated | -0.0433431 |
| SETD5 | SET domain containing 5 | -0.0429376 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0428795 |
| MEIS2 | Meis homeobox 2 | -0.0424957 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0419188 |
| CENPF | centromere protein F, 350/400kDa | -0.0417918 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0416038 |
| THBS1 | thrombospondin 1 | -0.0415528 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.041422 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0413956 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0411171 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0410524 |
| RHEB | Ras homolog enriched in brain | -0.0405831 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0403802 |
| MAP4 | microtubule-associated protein 4 | -0.0400126 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0395332 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0393566 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0390812 |
| LDHA | lactate dehydrogenase A | -0.038839 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0386759 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0382443 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | -0.0379564 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.037866 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0376451 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0375473 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0373615 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0369424 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0367946 |
| MTF2 | metal response element binding transcription factor 2 | -0.0367737 |
| S100A10 | S100 calcium binding protein A10 | -0.036743 |
| COL11A1 | collagen, type XI, alpha 1 | -0.036357 |
| FAM171B | family with sequence similarity 171, member B | -0.0363162 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0362349 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0359157 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0354225 |
| PGK1 | phosphoglycerate kinase 1 | -0.0350097 |
| TMEM123 | transmembrane protein 123 | -0.0348967 |
| RPL35A | ribosomal protein L35a | -0.0347308 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0344963 |
| RPLP1 | ribosomal protein, large, P1 | -0.0343514 |
