| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sulfisoxazole perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Sulfisoxazole_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.120954 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.114196 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0667225 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.066262 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0640039 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0624678 |
| NAV2 | neuron navigator 2 | 0.0595296 |
| HDAC9 | histone deacetylase 9 | 0.0529004 |
| PRELID2 | PRELI domain containing 2 | 0.0501019 |
| SQSTM1 | sequestosome 1 | 0.0478448 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0456089 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0453168 |
| NDRG1 | N-myc downstream regulated 1 | 0.0445577 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0421625 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.04057 |
| B2M | beta-2-microglobulin | 0.0386903 |
| EFNA5 | ephrin-A5 | 0.0360354 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0360031 |
| MT2A | metallothionein 2A | 0.0356643 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0346012 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0345968 |
| DUSP10 | dual specificity phosphatase 10 | 0.0345908 |
| ADM | adrenomedullin | 0.0339989 |
| RPS12 | ribosomal protein S12 | 0.0339363 |
| ASPH | aspartate beta-hydroxylase | 0.0337749 |
| RND3 | Rho family GTPase 3 | 0.0333629 |
| SEPTIN9 | septin 9 | 0.0333178 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0323843 |
| FMNL2 | formin-like 2 | 0.0318889 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0318257 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0318047 |
| ARFGEF3 | ARFGEF family member 3 | 0.0315554 |
| IRS2 | insulin receptor substrate 2 | 0.0310313 |
| FBXO32 | F-box protein 32 | 0.0308113 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0306807 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0303853 |
| STC1 | stanniocalcin 1 | 0.0303545 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0303004 |
| RPS6 | ribosomal protein S6 | 0.0302039 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0297904 |
| ZNF292 | zinc finger protein 292 | 0.0296778 |
| INTS6 | integrator complex subunit 6 | 0.0296485 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0295696 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0291484 |
| RUNX1 | runt-related transcription factor 1 | 0.0289824 |
| FNIP1 | folliculin interacting protein 1 | 0.0289108 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.028532 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.028493 |
| STC2 | stanniocalcin 2 | 0.0282665 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0279885 |
| GOLGA4 | golgin A4 | 0.0277204 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0274364 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0272132 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0271981 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0271681 |
| RPL4 | ribosomal protein L4 | 0.0270662 |
| COL5A1 | collagen, type V, alpha 1 | 0.0266527 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0265603 |
| DST | dystonin | 0.0256922 |
| CALR | calreticulin | 0.0256064 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0252519 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0252393 |
| MLPH | melanophilin | 0.0248635 |
| EGFR | epidermal growth factor receptor | 0.0247092 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0243652 |
| VAC14 | Vac14 homolog (S. cerevisiae) | 0.0241258 |
| RPS18 | ribosomal protein S18 | 0.0240359 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0239135 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.023895 |
| WWOX | WW domain containing oxidoreductase | 0.0236522 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0236343 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0231756 |
| MYO10 | myosin X | 0.0230935 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.022154 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0220702 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0216475 |
| HLA-A | major histocompatibility complex, class I, A | 0.0215587 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0214906 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.02143 |
| PDE10A | phosphodiesterase 10A | 0.0213316 |
| CDH13 | cadherin 13 | 0.0210336 |
| SMYD3 | SET and MYND domain containing 3 | 0.020808 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0206976 |
| PLIN2 | perilipin 2 | 0.0205264 |
| DTNA | dystrobrevin, alpha | 0.0204377 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 0.02015 |
| HELZ | helicase with zinc finger | 0.0199698 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0198765 |
| FHIT | fragile histidine triad | 0.0196463 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0195086 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0192355 |
| GPC6 | glypican 6 | 0.0188629 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0188412 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0186921 |
| PHF21A | PHD finger protein 21A | 0.0186861 |
| DUSP5 | dual specificity phosphatase 5 | 0.0186165 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0184154 |
| ENO1 | enolase 1, (alpha) | 0.0182744 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0179541 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0178846 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.235999 |
| VIM | vimentin | -0.153278 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.122972 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0991137 |
| VCL | vinculin | -0.0956278 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0918141 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0813514 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0709056 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0685112 |
| FRMD4A | FERM domain containing 4A | -0.06754 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0634139 |
| TPM4 | tropomyosin 4 | -0.058645 |
| GLIS3 | GLIS family zinc finger 3 | -0.0551671 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0543977 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0532858 |
| RTN4 | reticulon 4 | -0.0532804 |
| PGK1 | phosphoglycerate kinase 1 | -0.052324 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0509648 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0500757 |
| THBS1 | thrombospondin 1 | -0.0495623 |
| RAI14 | retinoic acid induced 14 | -0.0471717 |
| BICC1 | BicC family RNA binding protein 1 | -0.0468119 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0461953 |
| RPS24 | ribosomal protein S24 | -0.0459956 |
| PALLD | palladin, cytoskeletal associated protein | -0.0457914 |
| ACTG1 | actin gamma 1 | -0.045253 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0440858 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0438392 |
| WTAP | Wilms tumor 1 associated protein | -0.0414125 |
| CTSD | cathepsin D | -0.0412802 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0409961 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0408514 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.039907 |
| TMSB10 | thymosin beta 10 | -0.038171 |
| CLIC4 | chloride intracellular channel 4 | -0.0381421 |
| ANXA2 | annexin A2 | -0.0369321 |
| IER3 | immediate early response 3 | -0.0364082 |
| POTEF | POTE ankyrin domain family, member F | -0.0363123 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0354504 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0351562 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0346296 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0345714 |
| NABP1 | nucleic acid binding protein 1 | -0.0344052 |
| SBF2 | SET binding factor 2 | -0.0340223 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.033862 |
| EGR1 | early growth response 1 | -0.0333659 |
| ATP13A3 | ATPase type 13A3 | -0.0332745 |
| PTMA | prothymosin, alpha | -0.03265 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0323795 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0315202 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0313455 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0313418 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0311549 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0296099 |
| COL1A1 | collagen, type I, alpha 1 | -0.0290231 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0287785 |
| UBC | ubiquitin C | -0.0285236 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.027311 |
| SRGN | serglycin | -0.0271793 |
| TUBB | tubulin, beta class I | -0.0271536 |
| CAVIN1 | caveolae associated protein 1 | -0.0270812 |
| TMEM123 | transmembrane protein 123 | -0.026485 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0264089 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0263794 |
| ACTN1 | actinin, alpha 1 | -0.0262677 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0261533 |
| MKI67 | marker of proliferation Ki-67 | -0.026151 |
| KYNU | kynureninase | -0.0258573 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0258572 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0258002 |
| HDAC8 | histone deacetylase 8 | -0.025752 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0254627 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0253188 |
| HMGA1 | high mobility group AT-hook 1 | -0.0250141 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0247786 |
| TXNRD1 | thioredoxin reductase 1 | -0.0244823 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0244485 |
| VDAC1 | voltage-dependent anion channel 1 | -0.024063 |
| DENND5A | DENN/MADD domain containing 5A | -0.0239508 |
| FTL | ferritin, light polypeptide | -0.0238542 |
| SERINC3 | serine incorporator 3 | -0.0237132 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0236398 |
| TKT | transketolase | -0.0231852 |
| SMAD3 | SMAD family member 3 | -0.0230153 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0230046 |
| NF1 | neurofibromin 1 | -0.0228363 |
| OSMR | oncostatin M receptor | -0.0228189 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0228085 |
| MSN | moesin | -0.0227827 |
| RPLP0 | ribosomal protein, large, P0 | -0.0224082 |
| CALD1 | caldesmon 1 | -0.0222215 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0221673 |
| CLMP | CXADR-like membrane protein | -0.0217013 |
| TNNC1 | troponin C type 1 (slow) | -0.0216276 |
| PARD3 | par-3 family cell polarity regulator | -0.0214762 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0214113 |
| GNAS | GNAS complex locus | -0.0211724 |
| NRP1 | neuropilin 1 | -0.0210522 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0210377 |
| WASF2 | WAS protein family, member 2 | -0.0206872 |
