| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sulfisoxazole perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sulfisoxazole_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.179837 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.134016 |
| STC2 | stanniocalcin 2 | 0.118701 |
| ASPH | aspartate beta-hydroxylase | 0.103603 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0707727 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0684734 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0637487 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0612983 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0605339 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0585675 |
| PRRC2C | proline-rich coiled-coil 2C | 0.057471 |
| MT2A | metallothionein 2A | 0.0530584 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0528313 |
| VEGFA | vascular endothelial growth factor A | 0.0520476 |
| HLA-B | major histocompatibility complex, class I, B | 0.0503929 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0503908 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0500171 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0487394 |
| AREG | amphiregulin | 0.0460852 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0454752 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0447883 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0437279 |
| VIM | vimentin | 0.0429087 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0426548 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0406587 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0397327 |
| LMNA | lamin A/C | 0.0396729 |
| TMSB10 | thymosin beta 10 | 0.038782 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0374286 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0361466 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.036123 |
| NTN4 | netrin 4 | 0.036061 |
| FLNA | filamin A, alpha | 0.0356649 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0351665 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0351061 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0345212 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0335955 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0331985 |
| FLNB | filamin B, beta | 0.0328744 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.031786 |
| RPS6 | ribosomal protein S6 | 0.0317781 |
| ANGPTL4 | angiopoietin-like 4 | 0.0315248 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0315239 |
| ENO1 | enolase 1, (alpha) | 0.0313385 |
| DST | dystonin | 0.0313074 |
| DHFR | dihydrofolate reductase | 0.0301287 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0301161 |
| RBM39 | RNA binding motif protein 39 | 0.0300324 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0299841 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0298144 |
| PRELID2 | PRELI domain containing 2 | 0.0288215 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0280081 |
| RBM25 | RNA binding motif protein 25 | 0.0277404 |
| EZR | ezrin | 0.0275881 |
| PLEC | plectin | 0.0273599 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0273056 |
| RPS12 | ribosomal protein S12 | 0.0272083 |
| SMAD3 | SMAD family member 3 | 0.0271934 |
| PTMA | prothymosin, alpha | 0.0267829 |
| LOC112694756 | uncharaterized LOC112694756 | 0.026606 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0264968 |
| SMYD3 | SET and MYND domain containing 3 | 0.0263806 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0260929 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0260812 |
| SVIL | supervillin | 0.0258543 |
| HLA-A | major histocompatibility complex, class I, A | 0.0258122 |
| EGFR | epidermal growth factor receptor | 0.0254801 |
| ABLIM1 | actin binding LIM protein 1 | 0.0254407 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0253559 |
| NDRG1 | N-myc downstream regulated 1 | 0.0253235 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0251723 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0251118 |
| OGA | O-GlcNAcase | 0.0250512 |
| SEPTIN9 | septin 9 | 0.0250059 |
| MLPH | melanophilin | 0.0247784 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.024632 |
| EGR1 | early growth response 1 | 0.0246164 |
| RPL4 | ribosomal protein L4 | 0.0243098 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0242588 |
| GOLGA4 | golgin A4 | 0.0242096 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0241488 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0241203 |
| VEGFC | vascular endothelial growth factor C | 0.0239969 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0239707 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0239426 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0238301 |
| NRP1 | neuropilin 1 | 0.0230128 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0229129 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.022786 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.0226425 |
| TPM3 | tropomyosin 3 | 0.0225858 |
| CALR | calreticulin | 0.0224776 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0219702 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.021738 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0217125 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0214898 |
| AFDN | afadin, adherens junction formation factor | 0.0211574 |
| B2M | beta-2-microglobulin | 0.0211033 |
| TPR | translocated promoter region, nuclear basket protein | 0.0210264 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.020934 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.344169 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.287742 |
| NRG1 | neuregulin 1 | -0.165686 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.1433 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.129602 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.109203 |
| CANX | calnexin | -0.105626 |
| FN1 | fibronectin 1 | -0.103433 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0792611 |
| SQSTM1 | sequestosome 1 | -0.0784377 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0614902 |
| CENPF | centromere protein F, 350/400kDa | -0.057494 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0555927 |
| ITGA1 | integrin, alpha 1 | -0.0482864 |
| TMEM165 | transmembrane protein 165 | -0.0452768 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0437256 |
| AHR | aryl hydrocarbon receptor | -0.0435469 |
| TMEM263 | transmembrane protein 263 | -0.0404743 |
| SYT1 | synaptotagmin I | -0.0404356 |
| GOLT1B | golgi transport 1B | -0.0396782 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0385926 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0373953 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0364597 |
| RPS24 | ribosomal protein S24 | -0.0353185 |
| CLTC | clathrin, heavy chain (Hc) | -0.0342013 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0340422 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | -0.0325257 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0314265 |
| UBC | ubiquitin C | -0.0311939 |
| ETNK1 | ethanolamine kinase 1 | -0.0310773 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0307681 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0303683 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.029517 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0289427 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0289054 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0287117 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0286037 |
| LRRC23 | leucine rich repeat containing 23 | -0.028089 |
| NEK7 | NIMA-related kinase 7 | -0.0279585 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0277992 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0272094 |
| WDR45B | WD repeat domain 45B | -0.0272065 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0269731 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0268044 |
| S100A6 | S100 calcium binding protein A6 | -0.0267463 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.026714 |
| AEBP2 | AE binding protein 2 | -0.0262795 |
| CDCP1 | CUB domain containing protein 1 | -0.0262581 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0261098 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0260076 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0259951 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0256507 |
| CALU | calumenin | -0.0256479 |
| DENND5B | DENN/MADD domain containing 5B | -0.0256043 |
| TRAM1 | translocation associated membrane protein 1 | -0.0253504 |
| RHEB | Ras homolog enriched in brain | -0.024917 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0248028 |
| CLINT1 | clathrin interactor 1 | -0.0244655 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0242918 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0241294 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0239446 |
| ZFR | zinc finger RNA binding protein | -0.0237924 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | -0.0232443 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.0229591 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0228523 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0227668 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | -0.0223668 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0223296 |
| RLF | rearranged L-myc fusion | -0.0222269 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0219309 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0219172 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | -0.0218642 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.021843 |
| INTS6 | integrator complex subunit 6 | -0.0215437 |
| COG5 | component of oligomeric golgi complex 5 | -0.0213777 |
| CEP350 | centrosomal protein 350kDa | -0.0211763 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0210786 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.020858 |
| FBN1 | fibrillin 1 | -0.020814 |
| TENT2 | terminal nucleotidyltransferase 2 | -0.0207851 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0207737 |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A | -0.020617 |
| WTAP | Wilms tumor 1 associated protein | -0.0203666 |
| DNM1L | dynamin 1-like | -0.0203544 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0202202 |
| YME1L1 | YME1-like 1 ATPase | -0.0201692 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.020161 |
| SMOX | spermine oxidase | -0.0200214 |
| RPS25 | ribosomal protein S25 | -0.0199651 |
| GPR75-ASB3 | GPR75-ASB3 readthrough | -0.0196954 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0196447 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0194479 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0193849 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0193316 |
| ADAR | adenosine deaminase, RNA-specific | -0.019297 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.0192826 |
| UBQLN1 | ubiquilin 1 | -0.0191962 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0191116 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0190409 |
| H3-3B | H3.3 histone B | -0.0190129 |
