| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sunitinib perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sunitinib_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0895826 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0767926 |
| THBS2 | thrombospondin 2 | 0.0549894 |
| S100A10 | S100 calcium binding protein A10 | 0.0527134 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0482581 |
| ASPH | aspartate beta-hydroxylase | 0.0422246 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0391693 |
| FN1 | fibronectin 1 | 0.0341021 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0334949 |
| SEPTIN9 | septin 9 | 0.0333105 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0332044 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0330514 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0324215 |
| CDH13 | cadherin 13 | 0.0322394 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | 0.0302204 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0300386 |
| PLAT | plasminogen activator, tissue | 0.0300019 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0299621 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0298252 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0297803 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0281859 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0271057 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0270511 |
| MT1X | metallothionein 1X | 0.0265615 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0265605 |
| XPO1 | exportin 1 | 0.0262145 |
| TRAM2 | translocation associated membrane protein 2 | 0.0261124 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0257054 |
| COL3A1 | collagen, type III, alpha 1 | 0.0256181 |
| ANXA2 | annexin A2 | 0.0250968 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0241985 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0232502 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0228363 |
| FLT1 | fms-related tyrosine kinase 1 | 0.0225571 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0223377 |
| TLE4 | transducin-like enhancer of split 4 | 0.0223157 |
| MB21D2 | Mab-21 domain containing 2 | 0.0222543 |
| LRRC17 | leucine rich repeat containing 17 | 0.0217847 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.0216969 |
| SEPTIN7 | septin 7 | 0.0213826 |
| SFXN3 | sideroflexin 3 | 0.0210024 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0205982 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0204109 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0203226 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0201268 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0200263 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | 0.0199296 |
| DCLK2 | doublecortin-like kinase 2 | 0.0198149 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0195771 |
| SMAD3 | SMAD family member 3 | 0.0192952 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0188987 |
| DGKG | diacylglycerol kinase, gamma 90kDa | 0.0187502 |
| CD44 | CD44 molecule (Indian blood group) | 0.0184109 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0183888 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0183271 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0182422 |
| CAVIN1 | caveolae associated protein 1 | 0.0177964 |
| TMSB4X | thymosin beta 4, X-linked | 0.0175871 |
| RAI1 | retinoic acid induced 1 | 0.0173578 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0173559 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0173508 |
| FUS | FUS RNA binding protein | 0.0172995 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | 0.0172937 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0167729 |
| ZNF217 | zinc finger protein 217 | 0.0166774 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0166256 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0165511 |
| WDR26 | WD repeat domain 26 | 0.0164758 |
| SYTL3 | synaptotagmin-like 3 | 0.0163427 |
| RASA3 | RAS p21 protein activator 3 | 0.0162275 |
| MYO10 | myosin X | 0.0161879 |
| RPS24 | ribosomal protein S24 | 0.0161145 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0160701 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0160263 |
| SPNS2 | spinster homolog 2 (Drosophila) | 0.0159824 |
| SASH1 | SAM and SH3 domain containing 1 | 0.0159182 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0158101 |
| ITPRIPL2 | inositol 1,4,5-trisphosphate receptor interacting protein-like 2 | 0.0157091 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0154477 |
| FMN2 | formin 2 | 0.0153738 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0151004 |
| DIAPH3 | diaphanous-related formin 3 | 0.0150359 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0149838 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0149518 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0148959 |
| KRT81 | keratin 81, type II | 0.0148695 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0148629 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0148435 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.01478 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0145514 |
| APP | amyloid beta (A4) precursor protein | 0.0145258 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0143862 |
| ANLN | anillin, actin binding protein | 0.0143802 |
| FNIP2 | folliculin interacting protein 2 | 0.0142937 |
| TRIM37 | tripartite motif containing 37 | 0.0142737 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0142054 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.014001 |
| FAT1 | FAT atypical cadherin 1 | 0.0137799 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0137557 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0137543 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.318499 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.178752 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.168439 |
| TMSB10 | thymosin beta 10 | -0.156891 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.121007 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.105033 |
| VIM | vimentin | -0.104797 |
| LOX | lysyl oxidase | -0.0861529 |
| FBN1 | fibrillin 1 | -0.0777055 |
| MYADM | myeloid-associated differentiation marker | -0.0771926 |
| COL1A2 | collagen, type I, alpha 2 | -0.072968 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0641154 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0619843 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0541523 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.05366 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0535604 |
| COL5A2 | collagen, type V, alpha 2 | -0.0528847 |
| MAP1B | microtubule-associated protein 1B | -0.0507229 |
| S100A6 | S100 calcium binding protein A6 | -0.0499376 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0482868 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0470818 |
| B2M | beta-2-microglobulin | -0.0466361 |
| CSTB | cystatin B (stefin B) | -0.046192 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0452282 |
| POTEF | POTE ankyrin domain family, member F | -0.0433051 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0430976 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0419932 |
| TAGLN2 | transgelin 2 | -0.0417044 |
| COPA | coatomer protein complex, subunit alpha | -0.041548 |
| KIFAP3 | kinesin-associated protein 3 | -0.0401922 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0394605 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.039446 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0389771 |
| JAZF1 | JAZF zinc finger 1 | -0.0388113 |
| HLA-A | major histocompatibility complex, class I, A | -0.0381023 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0379752 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0373284 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0370098 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0369739 |
| NBEAL1 | neurobeachin-like 1 | -0.036892 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0365127 |
| LDHA | lactate dehydrogenase A | -0.0364419 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0363656 |
| MEIS2 | Meis homeobox 2 | -0.0362727 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0362325 |
| LMNA | lamin A/C | -0.0362013 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0358554 |
| L1CAM | L1 cell adhesion molecule | -0.0353302 |
| PTMA | prothymosin, alpha | -0.0351375 |
| FAM114A1 | family with sequence similarity 114, member A1 | -0.0341883 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0341423 |
| PKM | pyruvate kinase, muscle | -0.0335778 |
| DST | dystonin | -0.0328919 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0328135 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0326144 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0325326 |
| GOLGB1 | golgin B1 | -0.0323117 |
| RASAL2 | RAS protein activator like 2 | -0.0321151 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | -0.0318798 |
| EGFR | epidermal growth factor receptor | -0.0318726 |
| HDLBP | high density lipoprotein binding protein | -0.0312762 |
| EGR1 | early growth response 1 | -0.0312693 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0307837 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.030773 |
| CANX | calnexin | -0.0307272 |
| HSPB1 | heat shock 27kDa protein 1 | -0.03063 |
| FNIP1 | folliculin interacting protein 1 | -0.0305009 |
| FTL | ferritin, light polypeptide | -0.0302461 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0300118 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0298087 |
| PRELID2 | PRELI domain containing 2 | -0.029716 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0293138 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0293021 |
| NDRG1 | N-myc downstream regulated 1 | -0.0291711 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0291631 |
| SYT1 | synaptotagmin I | -0.0287032 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0284716 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0281085 |
| VEGFC | vascular endothelial growth factor C | -0.0279352 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.0276829 |
| EXOC6B | exocyst complex component 6B | -0.0275986 |
| VAT1 | vesicle amine transport 1 | -0.0275912 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0274069 |
| INSIG1 | insulin induced gene 1 | -0.0269003 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0263768 |
| MRC2 | mannose receptor, C type 2 | -0.0262035 |
| RPL37A | ribosomal protein L37a | -0.0259841 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0258628 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0258126 |
| EHBP1 | EH domain binding protein 1 | -0.0257529 |
| AUTS2 | autism susceptibility candidate 2 | -0.0255761 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0255759 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0253168 |
| VEGFA | vascular endothelial growth factor A | -0.0252293 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0249017 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0247856 |
| UBXN4 | UBX domain protein 4 | -0.0246812 |
| SBF2 | SET binding factor 2 | -0.0245308 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0244455 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.024423 |
