| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sunitinib perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sunitinib_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.114818 |
| VIM | vimentin | 0.110578 |
| MMP12 | matrix metallopeptidase 12 | 0.103862 |
| EHBP1 | EH domain binding protein 1 | 0.0959823 |
| ASPH | aspartate beta-hydroxylase | 0.0897786 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0823765 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0695074 |
| HMGA2 | high mobility group AT-hook 2 | 0.0638545 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0606148 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | 0.0552592 |
| BCHE | butyrylcholinesterase | 0.0549135 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0547609 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0520065 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0498114 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0486928 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.048259 |
| AREG | amphiregulin | 0.0455803 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.0453085 |
| RPS24 | ribosomal protein S24 | 0.0450712 |
| MTAP | methylthioadenosine phosphorylase | 0.0417945 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0416779 |
| TMEM41B | transmembrane protein 41B | 0.0409911 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0382832 |
| RPS27A | ribosomal protein S27a | 0.0372265 |
| ZNF804A | zinc finger protein 804A | 0.0360257 |
| NHSL1 | NHS-like 1 | 0.0359726 |
| ACTG1 | actin gamma 1 | 0.0352329 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0346843 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0339435 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0338313 |
| RPL35A | ribosomal protein L35a | 0.032124 |
| R3HDM2 | R3H domain containing 2 | 0.0317026 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0312478 |
| EDARADD | EDAR-associated death domain | 0.031016 |
| RPL31 | ribosomal protein L31 | 0.0299728 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.029775 |
| JMJD1C | jumonji domain containing 1C | 0.0295432 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0292246 |
| RPS29 | ribosomal protein S29 | 0.0279872 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0279628 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0276222 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | 0.0269395 |
| RPL7A | ribosomal protein L7a | 0.0267344 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | 0.0265275 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | 0.0264473 |
| CUX1 | cut-like homeobox 1 | 0.0264164 |
| RPS23 | ribosomal protein S23 | 0.0259463 |
| GANAB | glucosidase, alpha; neutral AB | 0.0255704 |
| RPL36A | ribosomal protein L36a | 0.0255645 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0248365 |
| RPL37 | ribosomal protein L37 | 0.0240189 |
| CMIP | c-Maf inducing protein | 0.0237114 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0236264 |
| NEBL | nebulette | 0.023262 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0231464 |
| RPL38 | ribosomal protein L38 | 0.0229915 |
| VMP1 | vacuole membrane protein 1 | 0.0229321 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 0.022916 |
| INTS6 | integrator complex subunit 6 | 0.0227981 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0226164 |
| MYPN | myopalladin | 0.0225676 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0224364 |
| RASAL2 | RAS protein activator like 2 | 0.0218926 |
| TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae) | 0.0214608 |
| TBCA | tubulin folding cofactor A | 0.0211957 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0209033 |
| BRI3BP | BRI3 binding protein | 0.0209011 |
| VCL | vinculin | 0.0208806 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0205946 |
| MCL1 | myeloid cell leukemia 1 | 0.0205719 |
| NABP1 | nucleic acid binding protein 1 | 0.0204737 |
| GCG | glucagon | 0.0204371 |
| TGIF1 | TGFB-induced factor homeobox 1 | 0.0204278 |
| PTMA | prothymosin, alpha | 0.0202072 |
| CLDN1 | claudin 1 | 0.0201775 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0199234 |
| RPS21 | ribosomal protein S21 | 0.0193463 |
| PCNX4 | pecanex 4 | 0.0191716 |
| PTRH2 | peptidyl-tRNA hydrolase 2 | 0.0187999 |
| GPR75-ASB3 | GPR75-ASB3 readthrough | 0.0186908 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | 0.0181817 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0181596 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0177528 |
| PRKAG1 | protein kinase, AMP-activated, gamma 1 non-catalytic subunit | 0.0175831 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0175495 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0172689 |
| GLG1 | golgi glycoprotein 1 | 0.0172533 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0170349 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0168729 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0168134 |
| AHNAK | AHNAK nucleoprotein | 0.0167898 |
| RAN | RAN, member RAS oncogene family | 0.0167654 |
| BMPR1B | bone morphogenetic protein receptor, type IB | 0.0167565 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0166584 |
| FAF2 | Fas associated factor family member 2 | 0.0165818 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | 0.0165792 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.016568 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0164349 |
| RPS25 | ribosomal protein S25 | 0.0163736 |
| XRN2 | 5'-3' exoribonuclease 2 | 0.0163011 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.165723 |
| NLGN1 | neuroligin 1 | -0.117727 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.078789 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0784526 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0750664 |
| PFN1 | profilin 1 | -0.0749472 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0730345 |
| PCBP2 | poly(rC) binding protein 2 | -0.0671156 |
| PTMS | parathymosin | -0.0636765 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0613764 |
| YBX3 | Y box binding protein 3 | -0.0593463 |
| KIF5B | kinesin family member 5B | -0.0581804 |
| LDHA | lactate dehydrogenase A | -0.0560826 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0559971 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0554779 |
| POTEF | POTE ankyrin domain family, member F | -0.0545207 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0540759 |
| TMSB10 | thymosin beta 10 | -0.0537753 |
| ANXA1 | annexin A1 | -0.0532236 |
| FTL | ferritin, light polypeptide | -0.0518709 |
| TPM3 | tropomyosin 3 | -0.0508752 |
| CCDC88A | coiled-coil domain containing 88A | -0.0491103 |
| CENPF | centromere protein F, 350/400kDa | -0.0484997 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0484096 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.0478978 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0465359 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0464756 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0464124 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0461945 |
| RPL23 | ribosomal protein L23 | -0.0450871 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0446761 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0440966 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0435978 |
| HMGA1 | high mobility group AT-hook 1 | -0.0434382 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0433186 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0426095 |
| YBX1 | Y box binding protein 1 | -0.0422341 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0418607 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0412508 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0376461 |
| PLK2 | polo-like kinase 2 | -0.0375729 |
| U2SURP | U2 snRNP-associated SURP domain containing | -0.0372859 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0372136 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.036863 |
| TBK1 | TANK-binding kinase 1 | -0.0361254 |
| XPO1 | exportin 1 | -0.0358538 |
| CPOX | coproporphyrinogen oxidase | -0.0357183 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0356771 |
| GOLGA4 | golgin A4 | -0.0352237 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0345705 |
| TFG | TRK-fused gene | -0.0345607 |
| LDHB | lactate dehydrogenase B | -0.0344476 |
| GNAS | GNAS complex locus | -0.0341231 |
| CCNL1 | cyclin L1 | -0.0340709 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0337926 |
| SRRM1 | serine/arginine repetitive matrix 1 | -0.0337436 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0335019 |
| SET | SET nuclear proto-oncogene | -0.0334168 |
| CDK6 | cyclin-dependent kinase 6 | -0.0329901 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0326133 |
| ZNF292 | zinc finger protein 292 | -0.0323967 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.032122 |
| WDR43 | WD repeat domain 43 | -0.0320312 |
| TPI1 | triosephosphate isomerase 1 | -0.0317637 |
| PNN | pinin, desmosome associated protein | -0.0315041 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0311948 |
| SYT1 | synaptotagmin I | -0.0311264 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0310374 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0307208 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0306954 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0306162 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0306099 |
| OGA | O-GlcNAcase | -0.0301652 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0300464 |
| HMGB2 | high mobility group box 2 | -0.0297027 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0295628 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0292512 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0291755 |
| SON | SON DNA binding protein | -0.0290869 |
| RACK1 | receptor for activated C kinase 1 | -0.0289481 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.0288068 |
| RPL18 | ribosomal protein L18 | -0.0286227 |
| CCN2 | cellular communication network factor 2 | -0.028447 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.028135 |
| NOP58 | NOP58 ribonucleoprotein | -0.0280732 |
| RPS4X | ribosomal protein S4, X-linked | -0.028041 |
| EPHA6 | EPH receptor A6 | -0.0278084 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0274008 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0273841 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0273513 |
| RLF | rearranged L-myc fusion | -0.0271127 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0269418 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0267388 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | -0.0266331 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0265811 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0264283 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0263987 |
| CBX3 | chromobox homolog 3 | -0.0263548 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0263161 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0262714 |
