| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sunitinib perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Sunitinib_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.147422 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.137974 |
| TXNRD1 | thioredoxin reductase 1 | 0.114793 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.106513 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0843532 |
| AHNAK | AHNAK nucleoprotein | 0.0540605 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0505862 |
| TMSB4X | thymosin beta 4, X-linked | 0.0500474 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0489034 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0454416 |
| USP34 | ubiquitin specific peptidase 34 | 0.0434436 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0432862 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0414067 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0403357 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0379036 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0372091 |
| PYGL | phosphorylase, glycogen, liver | 0.0369816 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0348257 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0348107 |
| RAI1 | retinoic acid induced 1 | 0.0319858 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0304027 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0303805 |
| NAV2 | neuron navigator 2 | 0.0299962 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.02993 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.029325 |
| EREG | epiregulin | 0.0291572 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0288416 |
| TP63 | tumor protein p63 | 0.0287799 |
| EHBP1 | EH domain binding protein 1 | 0.0287309 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0274892 |
| CMIP | c-Maf inducing protein | 0.0270352 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | 0.0262767 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0259883 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0257492 |
| ZNF217 | zinc finger protein 217 | 0.0253949 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0249628 |
| LOXL2 | lysyl oxidase-like 2 | 0.0248908 |
| UPP1 | uridine phosphorylase 1 | 0.024004 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0239373 |
| RGS4 | regulator of G-protein signaling 4 | 0.0237905 |
| YEATS2 | YEATS domain containing 2 | 0.0236983 |
| CCDC47 | coiled-coil domain containing 47 | 0.02312 |
| RPS24 | ribosomal protein S24 | 0.0228314 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0225891 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0225 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0221811 |
| CAVIN1 | caveolae associated protein 1 | 0.0220856 |
| APP | amyloid beta (A4) precursor protein | 0.0220676 |
| KLF6 | Kruppel-like factor 6 | 0.0220582 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0219556 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0217713 |
| CDK13 | cyclin-dependent kinase 13 | 0.021441 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0213643 |
| DENND1A | DENN/MADD domain containing 1A | 0.0209206 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.020719 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0203167 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0202724 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0202001 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.019951 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.019887 |
| EMP1 | epithelial membrane protein 1 | 0.0197614 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0196697 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0194384 |
| FNIP1 | folliculin interacting protein 1 | 0.0192584 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0191589 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0190739 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0187908 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0185897 |
| POM121 | POM121 transmembrane nucleoporin | 0.0184523 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0183154 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0183046 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0181535 |
| PDE10A | phosphodiesterase 10A | 0.0176891 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0176153 |
| CANX | calnexin | 0.0173981 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.017233 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | 0.0170046 |
| TMEM41B | transmembrane protein 41B | 0.0167516 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0167497 |
| NF1 | neurofibromin 1 | 0.0166031 |
| CLTC | clathrin, heavy chain (Hc) | 0.0165453 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0164715 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0164002 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0162395 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.01611 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0159157 |
| EXOC4 | exocyst complex component 4 | 0.0158937 |
| SRGN | serglycin | 0.0158779 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0157521 |
| AK4 | adenylate kinase 4 | 0.0156365 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0156233 |
| MYOF | myoferlin | 0.0155604 |
| TNS3 | tensin 3 | 0.0154125 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0154106 |
| RPS27A | ribosomal protein S27a | 0.015393 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.015304 |
| IGF2R | insulin-like growth factor 2 receptor | 0.015301 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0152802 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.015279 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0152206 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.184126 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.178413 |
| PTMA | prothymosin, alpha | -0.163383 |
| POTEF | POTE ankyrin domain family, member F | -0.124409 |
| MT2A | metallothionein 2A | -0.112885 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.101172 |
| FTL | ferritin, light polypeptide | -0.101003 |
| TMSB10 | thymosin beta 10 | -0.0868234 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0799963 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0784298 |
| VIM | vimentin | -0.0781568 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0729609 |
| TXNIP | thioredoxin interacting protein | -0.0617237 |
| RPS6 | ribosomal protein S6 | -0.0563497 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0538193 |
| HMGA1 | high mobility group AT-hook 1 | -0.0484692 |
| SPAG9 | sperm associated antigen 9 | -0.0469642 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.046699 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0453502 |
| TOP1 | topoisomerase (DNA) I | -0.0450607 |
| CCNL1 | cyclin L1 | -0.042769 |
| RPS19 | ribosomal protein S19 | -0.0404154 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0404106 |
| RPS12 | ribosomal protein S12 | -0.0397685 |
| CALR | calreticulin | -0.0387652 |
| YBX1 | Y box binding protein 1 | -0.0387637 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.038427 |
| PCBP2 | poly(rC) binding protein 2 | -0.0368952 |
| RPL23 | ribosomal protein L23 | -0.0365411 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0346446 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0341988 |
| RPL36 | ribosomal protein L36 | -0.0341031 |
| PKM | pyruvate kinase, muscle | -0.0329275 |
| GOLGA4 | golgin A4 | -0.0328472 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0328234 |
| BRD2 | bromodomain containing 2 | -0.0327825 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0319469 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.03184 |
| SET | SET nuclear proto-oncogene | -0.0316144 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0315555 |
| HLA-A | major histocompatibility complex, class I, A | -0.0314169 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0312382 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0304699 |
| WASF2 | WAS protein family, member 2 | -0.0299566 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0291161 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0288384 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0283874 |
| RPS8 | ribosomal protein S8 | -0.0282169 |
| EGR1 | early growth response 1 | -0.027863 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0276272 |
| PFN1 | profilin 1 | -0.0269208 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0268942 |
| DST | dystonin | -0.025886 |
| RPL5 | ribosomal protein L5 | -0.0255829 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0255139 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0251988 |
| NUP58 | nucleoporin 58 | -0.0249896 |
| ZNF292 | zinc finger protein 292 | -0.0249651 |
| SP100 | SP100 nuclear antigen | -0.0248659 |
| NDRG1 | N-myc downstream regulated 1 | -0.0248393 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0247041 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0245412 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.024116 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0240911 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0238523 |
| MYADM | myeloid-associated differentiation marker | -0.0238073 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0235318 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0234547 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0233909 |
| RPL37A | ribosomal protein L37a | -0.0233812 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0231073 |
| SRPK2 | SRSF protein kinase 2 | -0.0230321 |
| MT1E | metallothionein 1E | -0.0230306 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0228478 |
| FOSL1 | FOS-like antigen 1 | -0.0227616 |
| PHIP | pleckstrin homology domain interacting protein | -0.0226424 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0225729 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0224734 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0223317 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0218315 |
| SEPTIN7 | septin 7 | -0.0217913 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.021787 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0214856 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0212648 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0212054 |
| RPL19 | ribosomal protein L19 | -0.021108 |
| RPL28 | ribosomal protein L28 | -0.0210072 |
| ZNF207 | zinc finger protein 207 | -0.0209124 |
| SLK | STE20-like kinase | -0.0208771 |
| TPI1 | triosephosphate isomerase 1 | -0.0208739 |
| PER1 | period circadian clock 1 | -0.020829 |
| B2M | beta-2-microglobulin | -0.0207272 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0205027 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0204339 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0203198 |
| RNF145 | ring finger protein 145 | -0.0202043 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0199991 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0198655 |
| LDHA | lactate dehydrogenase A | -0.0198058 |
| RPL26 | ribosomal protein L26 | -0.0197012 |
