| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sunitinib perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sunitinib_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GLCCI1 | glucocorticoid induced 1 | 0.106288 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0929044 |
| CD44 | CD44 molecule (Indian blood group) | 0.0926516 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0917503 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0897394 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.087497 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0730076 |
| FAM20C | family with sequence similarity 20, member C | 0.0723836 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0712911 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.070499 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0663322 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0619491 |
| HMGA2 | high mobility group AT-hook 2 | 0.0609756 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0556666 |
| OSMR | oncostatin M receptor | 0.0552924 |
| NRP1 | neuropilin 1 | 0.0530089 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0492113 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0491744 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0491217 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0445693 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0442342 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0441944 |
| KYNU | kynureninase | 0.0417522 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0416582 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0403217 |
| NTN4 | netrin 4 | 0.0399117 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0394519 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0385796 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0371754 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0362325 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0358913 |
| VMP1 | vacuole membrane protein 1 | 0.0350343 |
| LOX | lysyl oxidase | 0.0349585 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0342812 |
| STC1 | stanniocalcin 1 | 0.03422 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0335241 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0332452 |
| IL6ST | interleukin 6 signal transducer | 0.0321446 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0313635 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0310083 |
| HAS2 | hyaluronan synthase 2 | 0.0307986 |
| NUMB | numb homolog (Drosophila) | 0.0306135 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0305737 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0303457 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0301866 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0283535 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0283326 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.027688 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0275813 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0269428 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0266926 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0266613 |
| ZNF804A | zinc finger protein 804A | 0.0258516 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | 0.0257074 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0256112 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0255164 |
| AHNAK | AHNAK nucleoprotein | 0.0251112 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0248134 |
| EHBP1 | EH domain binding protein 1 | 0.0246478 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.024443 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0242868 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0242666 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.023543 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.023319 |
| VCL | vinculin | 0.0231075 |
| SMAD3 | SMAD family member 3 | 0.0229495 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0226349 |
| STK38L | serine/threonine kinase 38 like | 0.0223652 |
| TOP1 | topoisomerase (DNA) I | 0.0223573 |
| EFNA5 | ephrin-A5 | 0.0223403 |
| TGM2 | transglutaminase 2 | 0.0222748 |
| ENOSF1 | enolase superfamily member 1 | 0.0221464 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | 0.0220692 |
| ETV6 | ets variant 6 | 0.0220527 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0219909 |
| RAD51B | RAD51 paralog B | 0.021849 |
| VRK2 | vaccinia related kinase 2 | 0.0217735 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0217575 |
| ADD3 | adducin 3 (gamma) | 0.0217385 |
| RNF149 | ring finger protein 149 | 0.0216948 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0216599 |
| PCNX1 | pecanex 1 | 0.0216311 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0216079 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0216021 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0214995 |
| ERBIN | erbb2 interacting protein | 0.0214031 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0212256 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.020895 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0207849 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0205911 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0201773 |
| BPTF | bromodomain PHD finger transcription factor | 0.019984 |
| ABI1 | abl-interactor 1 | 0.0199783 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.019953 |
| MYO10 | myosin X | 0.0199419 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0198124 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0197945 |
| MEIS1 | Meis homeobox 1 | 0.0196704 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0196246 |
| ATXN1 | ataxin 1 | 0.0195872 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.178555 |
| GOLGA4 | golgin A4 | -0.091976 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.083634 |
| FTL | ferritin, light polypeptide | -0.0807287 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0730781 |
| MEF2A | myocyte enhancer factor 2A | -0.0661744 |
| PCBP2 | poly(rC) binding protein 2 | -0.0628264 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0523438 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0505197 |
| NDRG1 | N-myc downstream regulated 1 | -0.0503353 |
| PTMA | prothymosin, alpha | -0.0490381 |
| RPLP1 | ribosomal protein, large, P1 | -0.0470171 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0468278 |
| RPS6 | ribosomal protein S6 | -0.0462568 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0461723 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0439759 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0439705 |
| FAM13A | family with sequence similarity 13, member A | -0.0432743 |
| VIM | vimentin | -0.0429743 |
| RPS12 | ribosomal protein S12 | -0.0426076 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0422323 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0421612 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0417089 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0410074 |
| CDH13 | cadherin 13 | -0.0408481 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0398185 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0388466 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0355866 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0350544 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0347397 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0340798 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.0339055 |
| RPS3 | ribosomal protein S3 | -0.033591 |
| RPL5 | ribosomal protein L5 | -0.0333112 |
| VEGFA | vascular endothelial growth factor A | -0.0324835 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0322009 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0321726 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.0306632 |
| ARF4 | ADP-ribosylation factor 4 | -0.0303933 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0301709 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0296883 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0296454 |
| RPL11 | ribosomal protein L11 | -0.0296361 |
| CALU | calumenin | -0.0295249 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.029455 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0293926 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0291512 |
| MORF4L2 | mortality factor 4 like 2 | -0.0288983 |
| COPA | coatomer protein complex, subunit alpha | -0.0285579 |
| NAV2 | neuron navigator 2 | -0.0284529 |
| SEC24A | SEC24 family member A | -0.0284409 |
| PKM | pyruvate kinase, muscle | -0.0283216 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0280971 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0276566 |
| RPL36 | ribosomal protein L36 | -0.027489 |
| RPL31 | ribosomal protein L31 | -0.0274822 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | -0.0271398 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0271065 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0270571 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0270173 |
| RPL37A | ribosomal protein L37a | -0.0270054 |
| RPL23 | ribosomal protein L23 | -0.026805 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0262416 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0262116 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0261669 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | -0.0255908 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0252817 |
| RPS8 | ribosomal protein S8 | -0.0251314 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0245468 |
| HELZ | helicase with zinc finger | -0.0244424 |
| DTNA | dystrobrevin, alpha | -0.0244218 |
| YBX1 | Y box binding protein 1 | -0.0241137 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0238571 |
| CA12 | carbonic anhydrase XII | -0.0237535 |
| ZNF292 | zinc finger protein 292 | -0.0236673 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0235681 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0234182 |
| MT2A | metallothionein 2A | -0.0233064 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0232458 |
| RIOK3 | RIO kinase 3 | -0.0231097 |
| MTSS1 | metastasis suppressor 1 | -0.0230145 |
| EZR | ezrin | -0.0229314 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0227557 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0227346 |
| PYGL | phosphorylase, glycogen, liver | -0.0227248 |
| RPL28 | ribosomal protein L28 | -0.0224939 |
| FOSL1 | FOS-like antigen 1 | -0.0220006 |
| RPS17 | ribosomal protein S17 | -0.0219926 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0217037 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0215709 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0212806 |
| HM13 | histocompatibility (minor) 13 | -0.0211962 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0211793 |
| FBN1 | fibrillin 1 | -0.0209298 |
| LRRC8C | leucine rich repeat containing 8 family, member C | -0.0208432 |
| LDHA | lactate dehydrogenase A | -0.0208339 |
| MYADM | myeloid-associated differentiation marker | -0.020484 |
| BRD2 | bromodomain containing 2 | -0.0204117 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0203958 |
| RPS19 | ribosomal protein S19 | -0.0202844 |
