| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sunitinib perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sunitinib_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.125719 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.10025 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0928093 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.091583 |
| TXNRD1 | thioredoxin reductase 1 | 0.0911573 |
| ATOSA | atos homolog A | 0.0864518 |
| EGFR | epidermal growth factor receptor | 0.0828549 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0754274 |
| LMO7 | LIM domain 7 | 0.0733766 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.067626 |
| RPL26 | ribosomal protein L26 | 0.0660961 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0605756 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0597328 |
| FN1 | fibronectin 1 | 0.0596499 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0571062 |
| CLTC | clathrin, heavy chain (Hc) | 0.0559526 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | 0.0553321 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0546897 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0544142 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0529185 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0515152 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0495606 |
| FBXO11 | F-box protein 11 | 0.0478043 |
| MYO10 | myosin X | 0.0466402 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0464501 |
| ABHD17C | abhydrolase domain containing 17C | 0.0463552 |
| MMP1 | matrix metallopeptidase 1 | 0.0461237 |
| LAMB3 | laminin, beta 3 | 0.0458194 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0455531 |
| SQSTM1 | sequestosome 1 | 0.0444556 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0438268 |
| RACK1 | receptor for activated C kinase 1 | 0.0434802 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0427547 |
| LOXL2 | lysyl oxidase-like 2 | 0.0420133 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0413158 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0408476 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0402405 |
| RAI14 | retinoic acid induced 14 | 0.0402169 |
| KATNBL1 | katanin p80 subunit B-like 1 | 0.0401321 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0398369 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0394829 |
| DSCAM | Down syndrome cell adhesion molecule | 0.03946 |
| ZFR | zinc finger RNA binding protein | 0.0394161 |
| OSMR | oncostatin M receptor | 0.0391238 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0390007 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0385258 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.038288 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0375241 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0371083 |
| MYOF | myoferlin | 0.0366071 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0363145 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0362388 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.035755 |
| VCL | vinculin | 0.0348069 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0332596 |
| VGF | VGF nerve growth factor inducible | 0.032797 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0324511 |
| AK1 | adenylate kinase 1 | 0.0323156 |
| ERBIN | erbb2 interacting protein | 0.0319004 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0316701 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0316433 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0313803 |
| MED13 | mediator complex subunit 13 | 0.0313047 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0311768 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0310612 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0309464 |
| HPCAL1 | hippocalcin-like 1 | 0.0306558 |
| RPS8 | ribosomal protein S8 | 0.0301313 |
| PLEC | plectin | 0.0297813 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0297777 |
| ATF6 | activating transcription factor 6 | 0.0289051 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0288614 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0285223 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0285041 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0284798 |
| SMYD3 | SET and MYND domain containing 3 | 0.028172 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0280467 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0277265 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0274262 |
| NABP1 | nucleic acid binding protein 1 | 0.0273632 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0273615 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0272901 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0271794 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0267638 |
| KRT17 | keratin 17, type I | 0.0266646 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0265577 |
| HMGA2 | high mobility group AT-hook 2 | 0.0265319 |
| ASPH | aspartate beta-hydroxylase | 0.0264739 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0264514 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0264227 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0259879 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.025639 |
| JAK1 | Janus kinase 1 | 0.025607 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0251792 |
| SFTPA2 | surfactant protein A2 | 0.0251198 |
| LDHB | lactate dehydrogenase B | 0.0250043 |
| DOCK1 | dedicator of cytokinesis 1 | 0.024869 |
| USP34 | ubiquitin specific peptidase 34 | 0.0248467 |
| CCNL1 | cyclin L1 | 0.0247983 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0247456 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.226887 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.135792 |
| NDRG1 | N-myc downstream regulated 1 | -0.126865 |
| PTMA | prothymosin, alpha | -0.115344 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.112131 |
| CD109 | CD109 molecule | -0.0783145 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0711184 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0690872 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0683628 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0677548 |
| B2M | beta-2-microglobulin | -0.0668545 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0665447 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0646904 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0640643 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0615272 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0612011 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0592158 |
| HELZ | helicase with zinc finger | -0.0584518 |
| ENO1 | enolase 1, (alpha) | -0.0574408 |
| TPR | translocated promoter region, nuclear basket protein | -0.0559782 |
| PGK1 | phosphoglycerate kinase 1 | -0.0556516 |
| POTEF | POTE ankyrin domain family, member F | -0.0537707 |
| RNF145 | ring finger protein 145 | -0.0528467 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0523671 |
| TMSB10 | thymosin beta 10 | -0.0520258 |
| RPS15 | ribosomal protein S15 | -0.0509038 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0506162 |
| USP3 | ubiquitin specific peptidase 3 | -0.0495105 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0494558 |
| SPAG9 | sperm associated antigen 9 | -0.049355 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0487648 |
| FMN1 | formin 1 | -0.0486952 |
| RPL21 | ribosomal protein L21 | -0.0482673 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0477713 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0475992 |
| VIM | vimentin | -0.0464569 |
| ATP11B | ATPase, class VI, type 11B | -0.0453605 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0450524 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0442608 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0436378 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0429343 |
| TFG | TRK-fused gene | -0.0422844 |
| RYBP | RING1 and YY1 binding protein | -0.04141 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0407139 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0403213 |
| PHIP | pleckstrin homology domain interacting protein | -0.0397013 |
| EZR | ezrin | -0.0396323 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0393229 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0390215 |
| YAP1 | Yes-associated protein 1 | -0.0388544 |
| HBP1 | HMG-box transcription factor 1 | -0.0387597 |
| FAM162A | family with sequence similarity 162, member A | -0.0378578 |
| RCOR1 | REST corepressor 1 | -0.0376448 |
| SETD5 | SET domain containing 5 | -0.0375008 |
| GOLGA4 | golgin A4 | -0.0369732 |
| YEATS2 | YEATS domain containing 2 | -0.0364762 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0354691 |
| S100A6 | S100 calcium binding protein A6 | -0.0354685 |
| RNF24 | ring finger protein 24 | -0.035392 |
| FUS | FUS RNA binding protein | -0.0353562 |
| PUM1 | pumilio RNA-binding family member 1 | -0.0351705 |
| NKTR | natural killer cell triggering receptor | -0.0350374 |
| COG5 | component of oligomeric golgi complex 5 | -0.0340077 |
| RPS19 | ribosomal protein S19 | -0.033962 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0329571 |
| LMNA | lamin A/C | -0.0327521 |
| S100A10 | S100 calcium binding protein A10 | -0.0318332 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0318169 |
| RLF | rearranged L-myc fusion | -0.0316753 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0315081 |
| SEPTIN7 | septin 7 | -0.0314585 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0312227 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0311111 |
| CCNI | cyclin I | -0.0308788 |
| MYO6 | myosin VI | -0.0308622 |
| AFDN | afadin, adherens junction formation factor | -0.0307986 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0307392 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0307118 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0306417 |
| NF1 | neurofibromin 1 | -0.0304513 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0302645 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0302313 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0301996 |
| FOXO3 | forkhead box O3 | -0.0301943 |
| YBX3 | Y box binding protein 3 | -0.0301187 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 | -0.0295556 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0294127 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0293437 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0293413 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0292784 |
| NBAS | neuroblastoma amplified sequence | -0.0286421 |
| PCBP2 | poly(rC) binding protein 2 | -0.0284932 |
| SRPK2 | SRSF protein kinase 2 | -0.028438 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0283302 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0282926 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0279155 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0276444 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.027441 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0273027 |
| PAPOLA | poly(A) polymerase alpha | -0.0272477 |
