| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sunitinib perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Sunitinib_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0707342 |
| GRAMD1B | GRAM domain containing 1B | 0.0327739 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0273962 |
| RTN4 | reticulon 4 | 0.0266811 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0230419 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0227792 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0213459 |
| XPO1 | exportin 1 | 0.0195144 |
| TXNRD1 | thioredoxin reductase 1 | 0.0194988 |
| LATS2 | large tumor suppressor kinase 2 | 0.0184114 |
| CCNL1 | cyclin L1 | 0.0183444 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0180606 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0164139 |
| POTEF | POTE ankyrin domain family, member F | 0.0161917 |
| VMP1 | vacuole membrane protein 1 | 0.0161612 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0158602 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0155348 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0152015 |
| PKM | pyruvate kinase, muscle | 0.0151487 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0151078 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0151058 |
| MKI67 | marker of proliferation Ki-67 | 0.014993 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0149473 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.0148791 |
| COPA | coatomer protein complex, subunit alpha | 0.0145604 |
| PGK1 | phosphoglycerate kinase 1 | 0.0143181 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0141977 |
| PFKP | phosphofructokinase, platelet | 0.0141833 |
| MSN | moesin | 0.0139412 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0130567 |
| KIF2C | kinesin family member 2C | 0.0125718 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0122716 |
| SPAG9 | sperm associated antigen 9 | 0.0122585 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0120988 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0119597 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0118993 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0118274 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0116324 |
| XPO6 | exportin 6 | 0.0113651 |
| KIF18B | kinesin family member 18B | 0.0109881 |
| ZNF292 | zinc finger protein 292 | 0.0109815 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0109432 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0109249 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.0108397 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | 0.0106255 |
| GPSM2 | G-protein signaling modulator 2 | 0.0105926 |
| WASF2 | WAS protein family, member 2 | 0.010583 |
| TPX2 | TPX2, microtubule-associated | 0.0105065 |
| CTTNBP2NL | CTTNBP2 N-terminal like | 0.0102499 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0101555 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0100841 |
| FAM13A | family with sequence similarity 13, member A | 0.0100409 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0100204 |
| SGO2 | shugoshin 2 | 0.010016 |
| RNF169 | ring finger protein 169 | 0.00980015 |
| PPME1 | protein phosphatase methylesterase 1 | 0.00969764 |
| RAB6A | RAB6A, member RAS oncogene family | 0.00966013 |
| MSH6 | mutS homolog 6 | 0.00965413 |
| UBC | ubiquitin C | 0.00961132 |
| ATL2 | atlastin GTPase 2 | 0.00961042 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.00958905 |
| GATAD2B | GATA zinc finger domain containing 2B | 0.00932416 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.00915587 |
| TPM3 | tropomyosin 3 | 0.00912871 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.00910072 |
| ATP11A | ATPase, class VI, type 11A | 0.00907973 |
| PLIN3 | perilipin 3 | 0.00906849 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.00904064 |
| RAI1 | retinoic acid induced 1 | 0.00901013 |
| ZYX | zyxin | 0.00898128 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00897169 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | 0.00883433 |
| CDCP1 | CUB domain containing protein 1 | 0.00879403 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.00876243 |
| USP36 | ubiquitin specific peptidase 36 | 0.00869466 |
| KIF4A | kinesin family member 4A | 0.00866921 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.00866143 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.00863126 |
| KIF11 | kinesin family member 11 | 0.00850982 |
| RASA2 | RAS p21 protein activator 2 | 0.00847366 |
| ANKRD36 | ankyrin repeat domain 36 | 0.00842357 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.00841979 |
| PLS3 | plastin 3 | 0.00838426 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.00838239 |
| TMEM165 | transmembrane protein 165 | 0.00837724 |
| RFX7 | regulatory factor X, 7 | 0.00836455 |
| PER1 | period circadian clock 1 | 0.00833299 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.00825515 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00823618 |
| RECQL | RecQ helicase-like | 0.00822408 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.00817438 |
| YBX3 | Y box binding protein 3 | 0.00816626 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.00816174 |
| EPAS1 | endothelial PAS domain protein 1 | 0.00814788 |
| MEF2D | myocyte enhancer factor 2D | 0.00809137 |
| NUP58 | nucleoporin 58 | 0.0080363 |
| MORF4L2 | mortality factor 4 like 2 | 0.00802867 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.00798785 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.00795435 |
| CD164 | CD164 molecule, sialomucin | 0.00794877 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.042758 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0415424 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0413378 |
| RPL37 | ribosomal protein L37 | -0.0387763 |
| RPL26 | ribosomal protein L26 | -0.0382287 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0369268 |
| RPL37A | ribosomal protein L37a | -0.0358114 |
| RPS3 | ribosomal protein S3 | -0.0358114 |
| RPL23 | ribosomal protein L23 | -0.034624 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0341075 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.032268 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0316496 |
| AEBP2 | AE binding protein 2 | -0.0303249 |
| FBXO11 | F-box protein 11 | -0.0289736 |
| RPS8 | ribosomal protein S8 | -0.0288035 |
| TMSB10 | thymosin beta 10 | -0.0285992 |
| INTS6 | integrator complex subunit 6 | -0.02804 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0278167 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0275956 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0271812 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0257957 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0249727 |
| RPL12 | ribosomal protein L12 | -0.0248828 |
| VIM | vimentin | -0.0248607 |
| RPLP1 | ribosomal protein, large, P1 | -0.0248572 |
| RPS12 | ribosomal protein S12 | -0.0239183 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0238034 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0236659 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0235776 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0235076 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0232815 |
| SET | SET nuclear proto-oncogene | -0.0226689 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.022578 |
| RPS27A | ribosomal protein S27a | -0.0219023 |
| RPL9 | ribosomal protein L9 | -0.0218289 |
| WWOX | WW domain containing oxidoreductase | -0.0215362 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0214601 |
| RNF213 | ring finger protein 213 | -0.0212662 |
| RACK1 | receptor for activated C kinase 1 | -0.0210002 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0208284 |
| PTMA | prothymosin, alpha | -0.0204939 |
| AFF3 | AF4/FMR2 family, member 3 | -0.02048 |
| DENND5B | DENN/MADD domain containing 5B | -0.0199521 |
| VCL | vinculin | -0.0198501 |
| RPL11 | ribosomal protein L11 | -0.0193129 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.019254 |
| EXOC4 | exocyst complex component 4 | -0.0189022 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0188255 |
| RPL5 | ribosomal protein L5 | -0.018713 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0185698 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.018438 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0183616 |
| RBM39 | RNA binding motif protein 39 | -0.018272 |
| GPHN | gephyrin | -0.01806 |
| RPL36 | ribosomal protein L36 | -0.0178794 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0174912 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0173663 |
| PHF3 | PHD finger protein 3 | -0.0171249 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0170461 |
| PCNX1 | pecanex 1 | -0.0168234 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0165805 |
| RPS19 | ribosomal protein S19 | -0.0165558 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0164017 |
| PRELID2 | PRELI domain containing 2 | -0.0163629 |
| RPL19 | ribosomal protein L19 | -0.0163118 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0162944 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0161917 |
| DST | dystonin | -0.0161733 |
| CDK13 | cyclin-dependent kinase 13 | -0.0160782 |
| RAD51B | RAD51 paralog B | -0.0160459 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0160204 |
| GPATCH2L | G patch domain containing 2-like | -0.0160118 |
| NF1 | neurofibromin 1 | -0.0159194 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0157718 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0156729 |
| AHNAK | AHNAK nucleoprotein | -0.0156063 |
| RPL34 | ribosomal protein L34 | -0.0155666 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0153203 |
| SQSTM1 | sequestosome 1 | -0.0151669 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0151535 |
| GOLGB1 | golgin B1 | -0.0149611 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0148953 |
| RPS17 | ribosomal protein S17 | -0.0148677 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0147279 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0144482 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0141962 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0141426 |
| RYK | receptor-like tyrosine kinase | -0.0138385 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0136881 |
| CUX1 | cut-like homeobox 1 | -0.0136675 |
| ATG7 | autophagy related 7 | -0.0136553 |
| RYR3 | ryanodine receptor 3 | -0.0133387 |
| NABP1 | nucleic acid binding protein 1 | -0.0133367 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.013241 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0132121 |
| SEM1 | SEM1 26S proteasome subunit | -0.0131448 |
| PDE10A | phosphodiesterase 10A | -0.0129435 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | -0.0128834 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0127881 |
| RPS10 | ribosomal protein S10 | -0.0127865 |
