| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sunitinib perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sunitinib_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| UBC | ubiquitin C | 0.131194 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.120351 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.109284 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.104428 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0794897 |
| ASPH | aspartate beta-hydroxylase | 0.0672356 |
| POTEF | POTE ankyrin domain family, member F | 0.0589493 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0506217 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0499929 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0483096 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0481165 |
| ENO1 | enolase 1, (alpha) | 0.046365 |
| PCBP2 | poly(rC) binding protein 2 | 0.0415559 |
| FN1 | fibronectin 1 | 0.0402007 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0399899 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.039402 |
| CALR | calreticulin | 0.0382789 |
| CANX | calnexin | 0.0361389 |
| RPS27A | ribosomal protein S27a | 0.0354393 |
| HMGB2 | high mobility group box 2 | 0.034314 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0331543 |
| AHNAK | AHNAK nucleoprotein | 0.0328706 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.031679 |
| TPM3 | tropomyosin 3 | 0.0306904 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0300342 |
| LDHA | lactate dehydrogenase A | 0.0293213 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0289912 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0276133 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0276098 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0270698 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0267581 |
| PKM | pyruvate kinase, muscle | 0.0262963 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0257584 |
| LAMC2 | laminin, gamma 2 | 0.0254942 |
| SET | SET nuclear proto-oncogene | 0.0252961 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0247542 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.024466 |
| RPS3 | ribosomal protein S3 | 0.0243145 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0239692 |
| KRT7 | keratin 7, type II | 0.0234802 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0228137 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0224084 |
| APP | amyloid beta (A4) precursor protein | 0.0222591 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0215048 |
| PLEC | plectin | 0.0211917 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0206357 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0205689 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0202927 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0196851 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0196822 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0194682 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0189901 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0185454 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0185013 |
| MSN | moesin | 0.018468 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0183647 |
| CALU | calumenin | 0.0183408 |
| S100A6 | S100 calcium binding protein A6 | 0.0182854 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0182639 |
| RACK1 | receptor for activated C kinase 1 | 0.0181475 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0180993 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0177949 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0177776 |
| RPL23 | ribosomal protein L23 | 0.0175781 |
| HDGF | hepatoma-derived growth factor | 0.0173111 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0170285 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.016709 |
| PTMA | prothymosin, alpha | 0.0166273 |
| PAPOLA | poly(A) polymerase alpha | 0.0162458 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0160119 |
| G0S2 | G0/G1 switch 2 | 0.0159726 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0159169 |
| ARRDC3 | arrestin domain containing 3 | 0.0157599 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0156799 |
| TOP1 | topoisomerase (DNA) I | 0.0156657 |
| YTHDC1 | YTH domain containing 1 | 0.0155907 |
| TFG | TRK-fused gene | 0.0154518 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0153059 |
| KRT8 | keratin 8, type II | 0.0152197 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0151048 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0150494 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0149125 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0148616 |
| PLAU | plasminogen activator, urokinase | 0.0146181 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0146135 |
| ANXA2 | annexin A2 | 0.0144729 |
| FLNA | filamin A, alpha | 0.0143882 |
| RHOA | ras homolog family member A | 0.0142303 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0141785 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.014077 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0140197 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0139063 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0138535 |
| DIAPH1 | diaphanous-related formin 1 | 0.013798 |
| EPCAM | epithelial cell adhesion molecule | 0.0136598 |
| YBX1 | Y box binding protein 1 | 0.0136585 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0136049 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0135071 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0133354 |
| RPL3 | ribosomal protein L3 | 0.0132899 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL35A | ribosomal protein L35a | -0.0476288 |
| FTL | ferritin, light polypeptide | -0.0465119 |
| ACTG1 | actin gamma 1 | -0.0370642 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0296512 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0279892 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0267902 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0249578 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0223196 |
| FBXO32 | F-box protein 32 | -0.0212604 |
| EFNA5 | ephrin-A5 | -0.0196389 |
| RPLP1 | ribosomal protein, large, P1 | -0.019516 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0188926 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0184678 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0183713 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0172856 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0171263 |
| RPL34 | ribosomal protein L34 | -0.0164144 |
| CSTB | cystatin B (stefin B) | -0.0159257 |
| HLA-B | major histocompatibility complex, class I, B | -0.0151558 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0137034 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0136193 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0132242 |
| MT2A | metallothionein 2A | -0.0131514 |
| RPS21 | ribosomal protein S21 | -0.0129099 |
| RPS29 | ribosomal protein S29 | -0.0128236 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0128151 |
| S100A9 | S100 calcium binding protein A9 | -0.012524 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0125161 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0124622 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0123424 |
| S100A10 | S100 calcium binding protein A10 | -0.0122198 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0121607 |
| RPS19 | ribosomal protein S19 | -0.0118794 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0117673 |
| RPLP2 | ribosomal protein, large, P2 | -0.0117564 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0115047 |
| TMEM165 | transmembrane protein 165 | -0.0110546 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0108362 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0106759 |
| RAI14 | retinoic acid induced 14 | -0.0100176 |
| RPL38 | ribosomal protein L38 | -0.0100014 |
| FRMD5 | FERM domain containing 5 | -0.00972029 |
| RNF213 | ring finger protein 213 | -0.00951897 |
| LMO7 | LIM domain 7 | -0.00924634 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.00924171 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.00914903 |
| MX2 | MX dynamin-like GTPase 2 | -0.00909048 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.00869429 |
| RASAL2 | RAS protein activator like 2 | -0.00860768 |
| CAVIN1 | caveolae associated protein 1 | -0.0085986 |
| MYO1E | myosin IE | -0.00852214 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.00851235 |
| HLA-A | major histocompatibility complex, class I, A | -0.00837216 |
| RPS6 | ribosomal protein S6 | -0.00835663 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.00816007 |
| CD2AP | CD2-associated protein | -0.0080826 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha | -0.00804227 |
| FBXO34 | F-box protein 34 | -0.00788236 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.00751573 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.00743033 |
| RPS23 | ribosomal protein S23 | -0.0073722 |
| RPL32 | ribosomal protein L32 | -0.0073655 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.00734763 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.00721418 |
| TMSB10 | thymosin beta 10 | -0.00718706 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.00717116 |
| CCND1 | cyclin D1 | -0.0071072 |
| VCL | vinculin | -0.00709051 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.00707701 |
| RBM47 | RNA binding motif protein 47 | -0.0070291 |
| MACC1 | metastasis associated in colon cancer 1 | -0.00695616 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.00695477 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.00695146 |
| CDCP1 | CUB domain containing protein 1 | -0.00694791 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.00688237 |
| RRBP1 | ribosome binding protein 1 | -0.00687732 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.0068387 |
| UBAP1 | ubiquitin associated protein 1 | -0.00682037 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.00681549 |
| PALLD | palladin, cytoskeletal associated protein | -0.00672422 |
| FNIP1 | folliculin interacting protein 1 | -0.00671783 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0067166 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.00669979 |
| ARHGAP20 | Rho GTPase activating protein 20 | -0.00666896 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.00665754 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.00665209 |
| ETV6 | ets variant 6 | -0.00663111 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0065989 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.00653995 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0065054 |
| CTSD | cathepsin D | -0.00643535 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0063524 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.00635133 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.00629947 |
| MCU | mitochondrial calcium uniporter | -0.00629501 |
| PLSCR1 | phospholipid scramblase 1 | -0.00628288 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.00627642 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.00626282 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.00612527 |
| RAB7A | RAB7A, member RAS oncogene family | -0.00611378 |
