| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sunitinib perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sunitinib_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PM20D1 | peptidase M20 domain containing 1 | 0.0743709 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0604831 |
| ASPH | aspartate beta-hydroxylase | 0.059905 |
| GRAMD1B | GRAM domain containing 1B | 0.0582645 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0552552 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0504411 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0417568 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0366309 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.035651 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0343131 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0319294 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0314722 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0300308 |
| NEK7 | NIMA-related kinase 7 | 0.0297132 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0271967 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.0269744 |
| NCAM1 | neural cell adhesion molecule 1 | 0.026824 |
| MCL1 | myeloid cell leukemia 1 | 0.0252437 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0249277 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0247954 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0246213 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0245707 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0245156 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0245019 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0244643 |
| RGS2 | regulator of G-protein signaling 2 | 0.0236256 |
| PRELID2 | PRELI domain containing 2 | 0.0230445 |
| PCBP3 | poly(rC) binding protein 3 | 0.0220588 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0220264 |
| RAB3B | RAB3B, member RAS oncogene family | 0.0210359 |
| FMNL2 | formin-like 2 | 0.0207439 |
| BMP6 | bone morphogenetic protein 6 | 0.0201908 |
| STC1 | stanniocalcin 1 | 0.0198519 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0194304 |
| CTSL | cathepsin L | 0.0193418 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0182329 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | 0.0172661 |
| TNPO1 | transportin 1 | 0.0172117 |
| ANXA5 | annexin A5 | 0.0164783 |
| RPS2 | ribosomal protein S2 | 0.0163747 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0162861 |
| KYNU | kynureninase | 0.0158204 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0155744 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0153202 |
| MLKL | mixed lineage kinase domain-like | 0.0139234 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0138546 |
| ATP13A3 | ATPase type 13A3 | 0.0137164 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0134496 |
| FAT1 | FAT atypical cadherin 1 | 0.0134424 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0134271 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0134209 |
| BDNF | brain-derived neurotrophic factor | 0.0133596 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0132561 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0131969 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0131872 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.0131861 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0131844 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0131722 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0131424 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | 0.0129567 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0125931 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | 0.0124589 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0124225 |
| IPO7 | importin 7 | 0.0122617 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0119631 |
| XPO1 | exportin 1 | 0.0119265 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0118888 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0118884 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0118765 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.0116117 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.011596 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.011506 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0114952 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0114567 |
| GREM2 | gremlin 2, DAN family BMP antagonist | 0.0114195 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0113204 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0112635 |
| HDAC4 | histone deacetylase 4 | 0.0110895 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 0.0110762 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0110603 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.010979 |
| TEX10 | testis expressed 10 | 0.0109438 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.010866 |
| MATR3 | matrin 3 | 0.0108588 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0108266 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0107852 |
| ANLN | anillin, actin binding protein | 0.0107844 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.010732 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | 0.0105351 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0105199 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0105134 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0104327 |
| DENND3 | DENN/MADD domain containing 3 | 0.0103522 |
| RRM2 | ribonucleotide reductase M2 | 0.0103397 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.010235 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0100133 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | 0.010006 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.009995 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.00996851 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.00995859 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.152321 |
| TMSB10 | thymosin beta 10 | -0.129588 |
| VIM | vimentin | -0.121204 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0859207 |
| GDA | guanine deaminase | -0.0794586 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0753575 |
| PTMA | prothymosin, alpha | -0.0746496 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.073852 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0709516 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0697807 |
| RPS6 | ribosomal protein S6 | -0.0688297 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0660133 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0656027 |
| FN1 | fibronectin 1 | -0.0643565 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0635618 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0633036 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0617188 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.061526 |
| S100A6 | S100 calcium binding protein A6 | -0.060443 |
| FTL | ferritin, light polypeptide | -0.0594947 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0589724 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0586226 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0577722 |
| RPLP1 | ribosomal protein, large, P1 | -0.0515729 |
| SMYD3 | SET and MYND domain containing 3 | -0.0487804 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.045778 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0443326 |
| RPL37A | ribosomal protein L37a | -0.0435186 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0433339 |
| CANX | calnexin | -0.0414616 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0405342 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0405279 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0403632 |
| COL4A6 | collagen, type IV, alpha 6 | -0.0401402 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0389348 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0384627 |
| JMJD1C | jumonji domain containing 1C | -0.038302 |
| RPS3 | ribosomal protein S3 | -0.0379542 |
| RPL23 | ribosomal protein L23 | -0.0378875 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0378761 |
| RPS19 | ribosomal protein S19 | -0.0364465 |
| RPS12 | ribosomal protein S12 | -0.0363693 |
| RPL19 | ribosomal protein L19 | -0.0362255 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0352933 |
| RPL31 | ribosomal protein L31 | -0.0351691 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0344702 |
| RPL35A | ribosomal protein L35a | -0.0341821 |
| RPL12 | ribosomal protein L12 | -0.0341249 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0336757 |
| MT2A | metallothionein 2A | -0.0333248 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0329013 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0327291 |
| RPL26 | ribosomal protein L26 | -0.0325319 |
| RPS8 | ribosomal protein S8 | -0.0316832 |
| RPL36 | ribosomal protein L36 | -0.0315873 |
| EGR1 | early growth response 1 | -0.0313612 |
| RACK1 | receptor for activated C kinase 1 | -0.0313307 |
| RPL13A | ribosomal protein L13a | -0.0311959 |
| DNER | delta/notch-like EGF repeat containing | -0.0307763 |
| CALR | calreticulin | -0.0305107 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.030171 |
| RPL9 | ribosomal protein L9 | -0.0301612 |
| RPS14 | ribosomal protein S14 | -0.0299457 |
| PFN1 | profilin 1 | -0.0296239 |
| PTEN | phosphatase and tensin homolog | -0.0290153 |
| RPS27 | ribosomal protein S27 | -0.0287387 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0283295 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0281285 |
| HLA-A | major histocompatibility complex, class I, A | -0.028051 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0275694 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0273459 |
| PCBP2 | poly(rC) binding protein 2 | -0.0273426 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0270643 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0270634 |
| RPL34 | ribosomal protein L34 | -0.0270222 |
| RPS4X | ribosomal protein S4, X-linked | -0.0269739 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0268132 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.026048 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0258217 |
| CUX1 | cut-like homeobox 1 | -0.0256785 |
| SBF2 | SET binding factor 2 | -0.0255685 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0253768 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0251275 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0249718 |
| MAP1B | microtubule-associated protein 1B | -0.0247971 |
| HLA-B | major histocompatibility complex, class I, B | -0.0247606 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0246661 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0245136 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0243541 |
| RPL11 | ribosomal protein L11 | -0.0243337 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0240711 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0240102 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0238426 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0234056 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0233625 |
| RPLP2 | ribosomal protein, large, P2 | -0.0232926 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0232509 |
| NF1 | neurofibromin 1 | -0.0232085 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.023145 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0229259 |
