| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sunitinib perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sunitinib_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ANKRD33B | ankyrin repeat domain 33B | 0.0557891 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0480241 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0459769 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0446426 |
| NTM | neurotrimin | 0.0368076 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0363221 |
| RCOR1 | REST corepressor 1 | 0.0320786 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0296019 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0284913 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0284781 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0274165 |
| RIGI | RNA sensor RIG-I | 0.0271509 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0268053 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | 0.023725 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.023685 |
| COL1A2 | collagen, type I, alpha 2 | 0.0232253 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.0231488 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0230546 |
| MTCL1 | microtubule crosslinking factor 1 | 0.0227107 |
| NRG1 | neuregulin 1 | 0.0223869 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0223318 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0217976 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0211902 |
| BMPR1A | bone morphogenetic protein receptor, type IA | 0.021113 |
| HMCN1 | hemicentin 1 | 0.0209078 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0208885 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0207765 |
| CEP192 | centrosomal protein 192kDa | 0.020368 |
| DENND5B | DENN/MADD domain containing 5B | 0.0202016 |
| COL3A1 | collagen, type III, alpha 1 | 0.0201669 |
| MARS1 | methionyl-tRNA synthetase 1 | 0.0201519 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | 0.019963 |
| CEP44 | centrosomal protein 44kDa | 0.019868 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0196293 |
| R3HDM1 | R3H domain containing 1 | 0.0196214 |
| TEX11 | testis expressed 11 | 0.0193312 |
| NBEA | neurobeachin | 0.0190701 |
| SPECC1L | sperm antigen with calponin homology and coiled-coil domains 1-like | 0.0190264 |
| SUCLA2 | succinate-CoA ligase, ADP-forming, beta subunit | 0.0189109 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0188386 |
| UBN2 | ubinuclein 2 | 0.0186513 |
| INTS6 | integrator complex subunit 6 | 0.0184227 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0184103 |
| NBEAL1 | neurobeachin-like 1 | 0.0182918 |
| ZNF711 | zinc finger protein 711 | 0.0182871 |
| FAM219A | family with sequence similarity 219, member A | 0.0181511 |
| NEBL | nebulette | 0.0181436 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.0181326 |
| CDK12 | cyclin-dependent kinase 12 | 0.0181086 |
| GRAMD1B | GRAM domain containing 1B | 0.0180819 |
| ZSWIM5 | zinc finger, SWIM-type containing 5 | 0.0180472 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0178944 |
| CAVIN1 | caveolae associated protein 1 | 0.0178906 |
| SIK2 | salt-inducible kinase 2 | 0.0178809 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0178141 |
| AHNAK | AHNAK nucleoprotein | 0.0178058 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0177625 |
| HMBOX1 | homeobox containing 1 | 0.0177182 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 0.0175873 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0175793 |
| CEP95 | centrosomal protein 95kDa | 0.0174714 |
| CCDC138 | coiled-coil domain containing 138 | 0.0173292 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0172592 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0172162 |
| MCL1 | myeloid cell leukemia 1 | 0.0172059 |
| PHF3 | PHD finger protein 3 | 0.0171535 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0168263 |
| TET1 | tet methylcytosine dioxygenase 1 | 0.0167829 |
| H2AC6 | H2A clustered histone 6 | 0.016744 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0165572 |
| CTTNBP2NL | CTTNBP2 N-terminal like | 0.0165311 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.016498 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 | 0.0164675 |
| ANKRD11 | ankyrin repeat domain 11 | 0.016318 |
| RB1 | retinoblastoma 1 | 0.0162454 |
| B2M | beta-2-microglobulin | 0.0161876 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0161459 |
| IP6K1 | inositol hexakisphosphate kinase 1 | 0.0161367 |
| TESK2 | testis-specific kinase 2 | 0.0161163 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0160416 |
| ITSN2 | intersectin 2 | 0.0160285 |
| CAPN7 | calpain 7 | 0.0158365 |
| ATG7 | autophagy related 7 | 0.015781 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0155541 |
| NAV3 | neuron navigator 3 | 0.0155427 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0154784 |
| ANKRD27 | ankyrin repeat domain 27 (VPS9 domain) | 0.015418 |
| SNX14 | sorting nexin 14 | 0.0152626 |
| SAMD11 | sterile alpha motif domain containing 11 | 0.0152341 |
| APOE | apolipoprotein E | 0.0152077 |
| PHACTR4 | phosphatase and actin regulator 4 | 0.015193 |
| WDR33 | WD repeat domain 33 | 0.0151459 |
| LARP1B | La ribonucleoprotein domain family, member 1B | 0.015084 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0150802 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.015046 |
| ZBTB46 | zinc finger and BTB domain containing 46 | 0.0150226 |
| FOXP1 | forkhead box P1 | 0.014971 |
| VCL | vinculin | 0.0149413 |
| FOXO3 | forkhead box O3 | 0.0149154 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.014878 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.217203 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.187702 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.183342 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.140005 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.107301 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0994486 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0934187 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0908771 |
| PEG10 | paternally expressed 10 | -0.0902523 |
| DST | dystonin | -0.0897104 |
| COL5A2 | collagen, type V, alpha 2 | -0.0885941 |
| POTEF | POTE ankyrin domain family, member F | -0.0735534 |
| TMSB10 | thymosin beta 10 | -0.0706478 |
| ITGAV | integrin, alpha V | -0.0688273 |
| YBX1 | Y box binding protein 1 | -0.0630381 |
| PFN1 | profilin 1 | -0.0606219 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0593596 |
| ZNF292 | zinc finger protein 292 | -0.057931 |
| RPS6 | ribosomal protein S6 | -0.0558603 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0558265 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0550668 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.053683 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0530025 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0528084 |
| PGK1 | phosphoglycerate kinase 1 | -0.0525403 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0523811 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0521822 |
| TENM3 | teneurin transmembrane protein 3 | -0.0518971 |
| TPR | translocated promoter region, nuclear basket protein | -0.0468514 |
| RPLP1 | ribosomal protein, large, P1 | -0.0464734 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0461086 |
| SEPTIN7 | septin 7 | -0.0456693 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.045645 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0454105 |
| RAI1 | retinoic acid induced 1 | -0.0451739 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0440485 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.043684 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0436608 |
| HMGB1 | high mobility group box 1 | -0.0430666 |
| RPL19 | ribosomal protein L19 | -0.0428961 |
| MATR3 | matrin 3 | -0.0425377 |
| EMP1 | epithelial membrane protein 1 | -0.0418881 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | -0.0418015 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0417601 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0409892 |
| PCBP2 | poly(rC) binding protein 2 | -0.0408469 |
| RTN4 | reticulon 4 | -0.0407636 |
| RPL36 | ribosomal protein L36 | -0.0401967 |
| RPLP0 | ribosomal protein, large, P0 | -0.0400442 |
| RPS8 | ribosomal protein S8 | -0.0397871 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.0392759 |
| ACTG1 | actin gamma 1 | -0.0389911 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.038227 |
| RPS12 | ribosomal protein S12 | -0.0381698 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0380421 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0377593 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0375061 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0370295 |
| RPL11 | ribosomal protein L11 | -0.0370108 |
| TPM3 | tropomyosin 3 | -0.0367225 |
| RPS4X | ribosomal protein S4, X-linked | -0.0362373 |
| ANXA1 | annexin A1 | -0.0357365 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0355008 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0354706 |
| SNX6 | sorting nexin 6 | -0.035216 |
| DEK | DEK proto-oncogene | -0.0351086 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0350611 |
| H2AZ2 | H2A.Z variant histone 2 | -0.0347169 |
| CBX3 | chromobox homolog 3 | -0.0345694 |
| RPS23 | ribosomal protein S23 | -0.0341677 |
| RPLP2 | ribosomal protein, large, P2 | -0.0339667 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0338068 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -0.0335686 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0331939 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | -0.033076 |
| RPS19 | ribosomal protein S19 | -0.0328718 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0327784 |
| PTMA | prothymosin, alpha | -0.032566 |
| RPS21 | ribosomal protein S21 | -0.0325222 |
| RPL23 | ribosomal protein L23 | -0.0325083 |
| DSTN | destrin (actin depolymerizing factor) | -0.0319446 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0318262 |
| FBL | fibrillarin | -0.0314862 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0311735 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0311297 |
| RBM39 | RNA binding motif protein 39 | -0.0309411 |
| GNAS | GNAS complex locus | -0.0307731 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0306001 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0305099 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.030492 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0304019 |
| HDAC9 | histone deacetylase 9 | -0.0302642 |
| TMSB4X | thymosin beta 4, X-linked | -0.0299673 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0299361 |
| PRR16 | proline rich 16 | -0.0296924 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0295966 |
| DYNC1I2 | dynein, cytoplasmic 1, intermediate chain 2 | -0.029479 |
| TOX | thymocyte selection-associated high mobility group box | -0.0294028 |
| MTF2 | metal response element binding transcription factor 2 | -0.0293954 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0292624 |
