| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sunitinib perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sunitinib_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0700648 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0642326 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0613061 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0580481 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0559358 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0516617 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0515787 |
| VCL | vinculin | 0.0494946 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0455035 |
| MT2A | metallothionein 2A | 0.0453059 |
| GPC6 | glypican 6 | 0.0452258 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0404572 |
| HMGA2 | high mobility group AT-hook 2 | 0.0386323 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0378351 |
| SMYD3 | SET and MYND domain containing 3 | 0.0348127 |
| ATXN1 | ataxin 1 | 0.034165 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0332207 |
| CD44 | CD44 molecule (Indian blood group) | 0.0316076 |
| ASPH | aspartate beta-hydroxylase | 0.0301663 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0299522 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0293091 |
| GLIS3 | GLIS family zinc finger 3 | 0.0289965 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0285384 |
| EFNA5 | ephrin-A5 | 0.0279218 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0279188 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0267177 |
| NAV1 | neuron navigator 1 | 0.0264813 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0257442 |
| CDH13 | cadherin 13 | 0.0257428 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0256038 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0248681 |
| RIGI | RNA sensor RIG-I | 0.0238385 |
| NAV2 | neuron navigator 2 | 0.0228242 |
| PRELID2 | PRELI domain containing 2 | 0.0226332 |
| OSMR | oncostatin M receptor | 0.0225905 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0223443 |
| SEPTIN9 | septin 9 | 0.021547 |
| HDAC9 | histone deacetylase 9 | 0.0215301 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0209966 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0209169 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0209165 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0207338 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0206888 |
| RAD51B | RAD51 paralog B | 0.0204608 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0200385 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0199849 |
| FMN1 | formin 1 | 0.0199371 |
| MCL1 | myeloid cell leukemia 1 | 0.019858 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0195622 |
| RUNX1 | runt-related transcription factor 1 | 0.0191752 |
| ARFGEF3 | ARFGEF family member 3 | 0.0191712 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0191207 |
| STC1 | stanniocalcin 1 | 0.0187344 |
| TMEM132D | transmembrane protein 132D | 0.0185934 |
| BICC1 | BicC family RNA binding protein 1 | 0.0185866 |
| ADAM12 | ADAM metallopeptidase domain 12 | 0.0185631 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0183123 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0181637 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0181524 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0181212 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0176043 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0175799 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0174999 |
| WWOX | WW domain containing oxidoreductase | 0.017363 |
| GOLGB1 | golgin B1 | 0.0172729 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0171474 |
| PCBP3 | poly(rC) binding protein 3 | 0.017133 |
| NABP1 | nucleic acid binding protein 1 | 0.0170204 |
| STK17A | serine/threonine kinase 17a | 0.0168356 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0167788 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0165567 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0165236 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0164296 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.0163087 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0160531 |
| DUSP5 | dual specificity phosphatase 5 | 0.0160327 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.015943 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0158841 |
| EXOC4 | exocyst complex component 4 | 0.0158367 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0157793 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0157141 |
| CDCP1 | CUB domain containing protein 1 | 0.0157079 |
| EGFR | epidermal growth factor receptor | 0.0156123 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0155653 |
| FHIT | fragile histidine triad | 0.0154299 |
| MLPH | melanophilin | 0.0152066 |
| VMP1 | vacuole membrane protein 1 | 0.0151448 |
| BPTF | bromodomain PHD finger transcription factor | 0.0149266 |
| NPC1 | Niemann-Pick disease, type C1 | 0.014853 |
| FAM20C | family with sequence similarity 20, member C | 0.0146971 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0145708 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0145421 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0145385 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0144834 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0144591 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0142563 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.014183 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0140288 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0140049 |
| SP100 | SP100 nuclear antigen | 0.0139986 |
| Symbol | Name | Standardized Value |
|---|---|---|
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.139903 |
| FN1 | fibronectin 1 | -0.112426 |
| CADM1 | cell adhesion molecule 1 | -0.106531 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.104445 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0958079 |
| VIM | vimentin | -0.0853696 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0804987 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0796504 |
| ZNF292 | zinc finger protein 292 | -0.0754737 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0737964 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0707384 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0703486 |
| QKI | QKI, KH domain containing, RNA binding | -0.067415 |
| RPS6 | ribosomal protein S6 | -0.0609822 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0600154 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0576729 |
| SPAG9 | sperm associated antigen 9 | -0.0564531 |
| ADM | adrenomedullin | -0.0560952 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0485942 |
| HELZ | helicase with zinc finger | -0.0474263 |
| YBX1 | Y box binding protein 1 | -0.0465962 |
| WTAP | Wilms tumor 1 associated protein | -0.0457021 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0445297 |
| PCBP2 | poly(rC) binding protein 2 | -0.0439966 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0435357 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0431317 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0426835 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0421472 |
| RBM39 | RNA binding motif protein 39 | -0.0404503 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0400367 |
| OGA | O-GlcNAcase | -0.0400249 |
| RLF | rearranged L-myc fusion | -0.0381207 |
| ATP13A3 | ATPase type 13A3 | -0.0359196 |
| TMEM123 | transmembrane protein 123 | -0.0353005 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0349883 |
| TAPBP | TAP binding protein (tapasin) | -0.0349558 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0338777 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0336707 |
| GOLGA4 | golgin A4 | -0.0334886 |
| PGK1 | phosphoglycerate kinase 1 | -0.0332438 |
| TFG | TRK-fused gene | -0.0326179 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0325253 |
| PTMA | prothymosin, alpha | -0.0323569 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0321009 |
| MATR3 | matrin 3 | -0.0315613 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0315236 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0314365 |
| ZNF207 | zinc finger protein 207 | -0.0308277 |
| GNAS | GNAS complex locus | -0.0305813 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0305427 |
| RYBP | RING1 and YY1 binding protein | -0.0305113 |
| RPLP0 | ribosomal protein, large, P0 | -0.0297848 |
| HLA-A | major histocompatibility complex, class I, A | -0.0297259 |
| IER3 | immediate early response 3 | -0.0296771 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0292934 |
| SFTPA2 | surfactant protein A2 | -0.0289502 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0288769 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0285703 |
| UVRAG | UV radiation resistance associated | -0.0282799 |
| KIF13A | kinesin family member 13A | -0.0282471 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0278646 |
| NUP153 | nucleoporin 153kDa | -0.0271899 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0269295 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0267341 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0266527 |
| FTL | ferritin, light polypeptide | -0.0265433 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0263665 |
| LDHA | lactate dehydrogenase A | -0.0263325 |
| RNF145 | ring finger protein 145 | -0.0261311 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0260095 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0259291 |
| SEPTIN7 | septin 7 | -0.0256692 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0248509 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0244512 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0243747 |
| RPS8 | ribosomal protein S8 | -0.024216 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.0241381 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.023849 |
| OPTN | optineurin | -0.0237215 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.023455 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0233774 |
| FAM162A | family with sequence similarity 162, member A | -0.023266 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0230543 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0227332 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0226364 |
| RPL39 | ribosomal protein L39 | -0.0225083 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0223551 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0223029 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0222442 |
| WDR45B | WD repeat domain 45B | -0.0222366 |
| PHF21A | PHD finger protein 21A | -0.0219831 |
| TBC1D12 | TBC1 domain family, member 12 | -0.0219792 |
| RPLP1 | ribosomal protein, large, P1 | -0.02196 |
| CCNL1 | cyclin L1 | -0.0219333 |
| PHIP | pleckstrin homology domain interacting protein | -0.021629 |
| MYOF | myoferlin | -0.0215999 |
| USP37 | ubiquitin specific peptidase 37 | -0.0214052 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0210406 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0210249 |
| SETD5 | SET domain containing 5 | -0.0209903 |
