| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Sunitinib perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Sunitinib_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0895971 |
| DIAPH3 | diaphanous-related formin 3 | 0.0483862 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0475563 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0467203 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0440375 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0429682 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0428334 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0403541 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0397911 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.03844 |
| KIAA1958 | KIAA1958 | 0.0383943 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0375176 |
| CEP57 | centrosomal protein 57kDa | 0.0370792 |
| TUBA1B | tubulin, alpha 1b | 0.0365281 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0359223 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0354598 |
| SGO2 | shugoshin 2 | 0.0348633 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0336041 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0325271 |
| TXNRD1 | thioredoxin reductase 1 | 0.0324306 |
| CENPF | centromere protein F, 350/400kDa | 0.0316226 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0312224 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0309057 |
| CDYL | chromodomain protein, Y-like | 0.0308854 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0307472 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0306108 |
| SETD5 | SET domain containing 5 | 0.0300908 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0297798 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0289577 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0281941 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.027323 |
| GOLGA4 | golgin A4 | 0.0271837 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | 0.0269619 |
| CCNB1 | cyclin B1 | 0.0264471 |
| MKI67 | marker of proliferation Ki-67 | 0.026336 |
| ZBTB43 | zinc finger and BTB domain containing 43 | 0.0256518 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0255796 |
| NUP58 | nucleoporin 58 | 0.02543 |
| CLTC | clathrin, heavy chain (Hc) | 0.02527 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0248751 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0246968 |
| UBAC2 | UBA domain containing 2 | 0.0246203 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 | 0.0244143 |
| TCERG1 | transcription elongation regulator 1 | 0.0242643 |
| CLASP2 | cytoplasmic linker associated protein 2 | 0.0241911 |
| PCNP | PEST proteolytic signal containing nuclear protein | 0.0241658 |
| NCOR1 | nuclear receptor corepressor 1 | 0.024156 |
| TTK | TTK protein kinase | 0.0240671 |
| HMGB2 | high mobility group box 2 | 0.0239857 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0238762 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0238254 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | 0.0238077 |
| CWF19L2 | CWF19-like 2, cell cycle control (S. pombe) | 0.0236697 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0234179 |
| CIRSR | corepressor of RBPJ and splicing regulator | 0.0233986 |
| TMEM245 | transmembrane protein 245 | 0.0233329 |
| SMC5 | structural maintenance of chromosomes 5 | 0.0232187 |
| SNX14 | sorting nexin 14 | 0.0230541 |
| AK1 | adenylate kinase 1 | 0.0230366 |
| ECT2 | epithelial cell transforming 2 | 0.0227579 |
| ANLN | anillin, actin binding protein | 0.0227561 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0224847 |
| IMMT | inner membrane protein, mitochondrial | 0.0219985 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.021962 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase | 0.0217993 |
| CAPN7 | calpain 7 | 0.0216707 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0216354 |
| SYCP2 | synaptonemal complex protein 2 | 0.0215909 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0215624 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0215479 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0215323 |
| PRC1 | protein regulator of cytokinesis 1 | 0.0214793 |
| HECTD4 | HECT domain containing E3 ubiquitin protein ligase 4 | 0.0213413 |
| TPX2 | TPX2, microtubule-associated | 0.0212711 |
| ERGIC3 | ERGIC and golgi 3 | 0.0211957 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0210804 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.021079 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0210604 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0210383 |
| NONO | non-POU domain containing, octamer-binding | 0.0209144 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0209125 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0208977 |
| SPAG9 | sperm associated antigen 9 | 0.0205688 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.0205665 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0204831 |
| ATAD2B | ATPase family, AAA domain containing 2B | 0.0204579 |
| SCAMP2 | secretory carrier membrane protein 2 | 0.0202724 |
| LDLR | low density lipoprotein receptor | 0.0201564 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0201385 |
| CCNB2 | cyclin B2 | 0.0200649 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0198581 |
| SMAD5 | SMAD family member 5 | 0.0197701 |
| STRBP | spermatid perinuclear RNA binding protein | 0.0194957 |
| PLEKHA8 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8 | 0.0194843 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0194356 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.019423 |
| PSMF1 | proteasome (prosome, macropain) inhibitor subunit 1 (PI31) | 0.0192758 |
| HELZ | helicase with zinc finger | 0.0192073 |
| TMEM263 | transmembrane protein 263 | 0.0192028 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0192026 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.103534 |
| PTMA | prothymosin, alpha | -0.0931612 |
| EGR1 | early growth response 1 | -0.0734312 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0709855 |
| HMGA2 | high mobility group AT-hook 2 | -0.0666846 |
| PTK2 | protein tyrosine kinase 2 | -0.065383 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0652785 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0632301 |
| FLNB | filamin B, beta | -0.059836 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0584678 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0583939 |
| POTEF | POTE ankyrin domain family, member F | -0.0582354 |
| FMNL2 | formin-like 2 | -0.0574866 |
| ANXA2 | annexin A2 | -0.0544161 |
| INTS6 | integrator complex subunit 6 | -0.0542869 |
| CD44 | CD44 molecule (Indian blood group) | -0.0535173 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0524345 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0500091 |
| ANXA1 | annexin A1 | -0.0495307 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0490933 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0470333 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0452693 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0451864 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0450179 |
| PRKCA | protein kinase C, alpha | -0.0441177 |
| DST | dystonin | -0.043088 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0430562 |
| SQSTM1 | sequestosome 1 | -0.0430191 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.042629 |
| NDRG1 | N-myc downstream regulated 1 | -0.0422556 |
| RPL37 | ribosomal protein L37 | -0.0413747 |
| RAI14 | retinoic acid induced 14 | -0.0410151 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0406404 |
| PKM | pyruvate kinase, muscle | -0.0397687 |
| MT2A | metallothionein 2A | -0.0395769 |
| GNAS | GNAS complex locus | -0.0395258 |
| RIGI | RNA sensor RIG-I | -0.0392613 |
| IER3 | immediate early response 3 | -0.0388378 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0388176 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0379934 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0378611 |
| VIM | vimentin | -0.03729 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0372368 |
| ANGPTL4 | angiopoietin-like 4 | -0.0369234 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0368374 |
| ADM | adrenomedullin | -0.0361759 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0356072 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0355837 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0354441 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0352786 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0351669 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0348207 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0347224 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0345851 |
| PRSS23 | protease, serine, 23 | -0.0345656 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0341497 |
| VCL | vinculin | -0.0341388 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.033607 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0335604 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0332768 |
| FOXO3 | forkhead box O3 | -0.0332344 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.033154 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0328256 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0328114 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0323755 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0321977 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0321832 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0321129 |
| LDHA | lactate dehydrogenase A | -0.031398 |
| RPL31 | ribosomal protein L31 | -0.0302342 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0302248 |
| DTNA | dystrobrevin, alpha | -0.0299416 |
| VMP1 | vacuole membrane protein 1 | -0.029831 |
| RPS16 | ribosomal protein S16 | -0.0296487 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0295872 |
| DNER | delta/notch-like EGF repeat containing | -0.02897 |
| VEGFA | vascular endothelial growth factor A | -0.0289038 |
| EMP1 | epithelial membrane protein 1 | -0.0287292 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0285723 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0284832 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0282502 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.027966 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0277073 |
| MYO9B | myosin IXB | -0.0276085 |
| ERBIN | erbb2 interacting protein | -0.0275187 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0275061 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0274661 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0273396 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0273281 |
| RPL23 | ribosomal protein L23 | -0.0269634 |
| RUNX1 | runt-related transcription factor 1 | -0.0269446 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0268595 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0267748 |
| WDR70 | WD repeat domain 70 | -0.0263552 |
| AHNAK | AHNAK nucleoprotein | -0.026069 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0260168 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0257809 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | -0.025318 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0253156 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0252857 |
