Superficial Ulcer Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0333307
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Genes

225 genes associated with the disease Superficial Ulcer in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ABR active BCR-related
ACR acrosin
ADAM8 ADAM metallopeptidase domain 8
ADIPOQ adiponectin, C1Q and collagen domain containing
AHR aryl hydrocarbon receptor
AIF1 allograft inflammatory factor 1
APOE apolipoprotein E
AREG amphiregulin
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARSD arylsulfatase D
ASCC2 activating signal cointegrator 1 complex subunit 2
ASF1A anti-silencing function 1A histone chaperone
ATM ATM serine/threonine kinase
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
ATR ATR serine/threonine kinase
BEST1 bestrophin 1
BRCA1 breast cancer 1, early onset
CAPG capping protein (actin filament), gelsolin-like
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCDC103 coiled-coil domain containing 103
CCL21 chemokine (C-C motif) ligand 21
CCL3 chemokine (C-C motif) ligand 3
CCL8 chemokine (C-C motif) ligand 8
CCN1 cellular communication network factor 1
CCR2 chemokine (C-C motif) receptor 2
CD19 CD19 molecule
CD44 CD44 molecule (Indian blood group)
CD46 CD46 molecule, complement regulatory protein
CD68 CD68 molecule
CDKN2A cyclin-dependent kinase inhibitor 2A
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CHRM3 cholinergic receptor, muscarinic 3
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLDN1 claudin 1
CLDN7 claudin 7
CLEC1B C-type lectin domain family 1, member B
CLEC5A C-type lectin domain family 5, member A
CMC1 C-x(9)-C motif containing 1
CNN2 calponin 2
COL17A1 collagen, type XVII, alpha 1
COMMD1 copper metabolism (Murr1) domain containing 1
COMP cartilage oligomeric matrix protein
COX2
CPB1 carboxypeptidase B1 (tissue)
CRIP3 cysteine-rich protein 3
CRP C-reactive protein, pentraxin-related
CRYGD crystallin, gamma D
CSF1 colony stimulating factor 1 (macrophage)
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTSB cathepsin B
CTSK cathepsin K
CUX1 cut-like homeobox 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL8 chemokine (C-X-C motif) ligand 8
CYLD cylindromatosis (turban tumor syndrome)
DKK1 dickkopf WNT signaling pathway inhibitor 1
DMD dystrophin
DPP4 dipeptidyl-peptidase 4
DSG3 desmoglein 3
DSG4 desmoglein 4
EFL1 elongation factor like GTPase 1
EGF epidermal growth factor
EMP1 epithelial membrane protein 1
ENO1 enolase 1, (alpha)
ESR1 estrogen receptor 1
EXO1 exonuclease 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
FOXC1 forkhead box C1
FOXP3 forkhead box P3
GADD45G growth arrest and DNA-damage-inducible, gamma
GDF15 growth differentiation factor 15
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
H2AX H2A.X variant histone
HAVCR1 hepatitis A virus cellular receptor 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-B major histocompatibility complex, class I, B
HLA-DMB major histocompatibility complex, class II, DM beta
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
HPX hemopexin
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IFNL1 interferon, lambda 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL10 interleukin 10
IL17A interleukin 17A
IL17B interleukin 17B
IL17D interleukin 17D
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL23A interleukin 23, alpha subunit p19
IL23R interleukin 23 receptor
IL27 interleukin 27
IL2RB interleukin 2 receptor, beta
IL32 interleukin 32
IL34 interleukin 34
IL36RN interleukin 36 receptor antagonist
IL4 interleukin 4
IL4R interleukin 4 receptor
IL6 interleukin 6
IL7 interleukin 7
IMPACT impact RWD domain protein
IRAK1 interleukin-1 receptor-associated kinase 1
IRF5 interferon regulatory factor 5
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
JAK2 Janus kinase 2
KIR3DS1 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
LRP5 low density lipoprotein receptor-related protein 5
MAG myelin associated glycoprotein
MAPK3 mitogen-activated protein kinase 3
MBL2 mannose-binding lectin (protein C) 2, soluble
MMP1 matrix metallopeptidase 1
MMP13 matrix metallopeptidase 13
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MMUT methylmalonyl-CoA mutase
MPG N-methylpurine-DNA glycosylase
MTX1 metaxin 1
MYDGF myeloid-derived growth factor
MYO9B myosin IXB
NBEAL1 neurobeachin-like 1
NCOA5 nuclear receptor coactivator 5
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NOD2 nucleotide-binding oligomerization domain containing 2
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NOTCH1 notch 1
NOX1 NADPH oxidase 1
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
ODF1 outer dense fiber of sperm tails 1
OMP olfactory marker protein
OSM oncostatin M
PADI4 peptidyl arginine deiminase, type IV
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PHEX phosphate regulating endopeptidase homolog, X-linked
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PMEL premelanosome protein
POLG polymerase (DNA directed), gamma
POSTN periostin, osteoblast specific factor
PPIA peptidylprolyl isomerase A (cyclophilin A)
PRDM9 PR domain containing 9
PRDX2 peroxiredoxin 2
PRTN3 proteinase 3
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RAD51B RAD51 paralog B
RAG2 recombination activating gene 2
RBM45 RNA binding motif protein 45
RMC1 regulator of MON1-CCZ1
RTEL1 regulator of telomere elongation helicase 1
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SART3 squamous cell carcinoma antigen recognized by T cells 3
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SH3BP2 SH3-domain binding protein 2
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SND1 staphylococcal nuclease and tudor domain containing 1
SOX5 SRY (sex determining region Y)-box 5
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPHK1 sphingosine kinase 1
SPP1 secreted phosphoprotein 1
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1
SRI sorcin
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STATH statherin
SYK spleen tyrosine kinase
TBPL1 TBP-like 1
TERF2 telomeric repeat binding factor 2
TERT telomerase reverse transcriptase
TGFB1 transforming growth factor, beta 1
TGFBI transforming growth factor, beta-induced, 68kDa
THBS1 thrombospondin 1
THBS2 thrombospondin 2
TIMD4 T-cell immunoglobulin and mucin domain containing 4
TIMELESS timeless circadian clock
TIMP1 TIMP metallopeptidase inhibitor 1
TLR2 toll-like receptor 2
TNF tumor necrosis factor
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TP53 tumor protein p53
TPI1 triosephosphate isomerase 1
TPO thyroid peroxidase
TPX2 TPX2, microtubule-associated
TRAF1 TNF receptor-associated factor 1
TRAP triiodothyronine receptor auxiliary protein
TSPO translocator protein (18kDa)
TWNK twinkle mtDNA helicase
UBXN11 UBX domain protein 11
URI1 URI1, prefoldin-like chaperone
VCAM1 vascular cell adhesion molecule 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VIM vimentin
WIF1 WNT inhibitory factor 1
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1