Synovial Sarcoma Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A synovium cancer which develops in the synovial membrane of the joints. (Human Disease Ontology, DOID_5485)
External Link https://www.disgenet.org/browser/0/1/0/C0039101
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Genes

280 genes associated with the disease Synovial Sarcoma in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ACE angiotensin I converting enzyme
ADAM17 ADAM metallopeptidase domain 17
ADIPOQ adiponectin, C1Q and collagen domain containing
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
ALB albumin
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALK anaplastic lymphoma receptor tyrosine kinase
ANKRD36B ankyrin repeat domain 36B
APC adenomatous polyposis coli
AQP5 aquaporin 5
AQP8 aquaporin 8
AQP9 aquaporin 9
ARR3 arrestin 3, retinal (X-arrestin)
ATF2 activating transcription factor 2
ATR ATR serine/threonine kinase
ATRX alpha thalassemia/mental retardation syndrome X-linked
AXIN2 axin 2
BANF1 barrier to autointegration factor 1
BCL2 B-cell CLL/lymphoma 2
BCL6 B-cell CLL/lymphoma 6
BCOR BCL6 corepressor
BCR breakpoint cluster region
BIK BCL2-interacting killer (apoptosis-inducing)
BMP6 bone morphogenetic protein 6
BRD9 bromodomain containing 9
CASR calcium-sensing receptor
CAV1 caveolin 1, caveolae protein, 22kDa
CCNB3 cyclin B3
CCND1 cyclin D1
CD274 CD274 molecule
CD34 CD34 molecule
CD38 CD38 molecule
CD68 CD68 molecule
CD99 CD99 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK4 cyclin-dependent kinase 4
CDK9 cyclin-dependent kinase 9
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN3 cyclin-dependent kinase inhibitor 3
CFB complement factor B
CIB1 calcium and integrin binding 1 (calmyrin)
CIC capicua transcriptional repressor
CLDN7 claudin 7
CRABP1 cellular retinoic acid binding protein 1
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CSK c-src tyrosine kinase
CTAG1A cancer/testis antigen 1A
CTAG1B cancer/testis antigen 1B
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSS cathepsin S
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXADR coxsackie virus and adenovirus receptor
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR4 chemokine (C-X-C motif) receptor 4
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DUSP6 dual specificity phosphatase 6
DUX4 double homeobox 4
DYM dymeclin
EGFR epidermal growth factor receptor
EGR1 early growth response 1
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ELK1 ELK1, member of ETS oncogene family
ENO2 enolase 2 (gamma, neuronal)
EP300 E1A binding protein p300
EPHB2 EPH receptor B2
ERBB2 erb-b2 receptor tyrosine kinase 2
ERCC5 excision repair cross-complementation group 5
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ESR1 estrogen receptor 1
ETFA electron-transfer-flavoprotein, alpha polypeptide
EWSR1 EWS RNA-binding protein 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
EZR ezrin
F2 coagulation factor II (thrombin)
F2RL1 coagulation factor II (thrombin) receptor-like 1
F5 coagulation factor V (proaccelerin, labile factor)
FASLG Fas ligand (TNF superfamily, member 6)
FGFR2 fibroblast growth factor receptor 2
FLVCR1 feline leukemia virus subgroup C cellular receptor 1
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FOXM1 forkhead box M1
FOXO1 forkhead box O1
FRMPD2 FERM and PDZ domain containing 2
FXYD5 FXYD domain containing ion transport regulator 5
FZD10 frizzled class receptor 10
GAB1 GRB2-associated binding protein 1
GDF6 growth differentiation factor 6
GINS1 GINS complex subunit 1 (Psf1 homolog)
GLB1 galactosidase, beta 1
GLO1 glyoxalase I
GRAP2 GRB2-related adaptor protein 2
GSK3B glycogen synthase kinase 3 beta
HBA1 hemoglobin, alpha 1
HBA2 hemoglobin, alpha 2
HBB hemoglobin, beta
HBG1 hemoglobin, gamma A
HBG2 hemoglobin, gamma G
HDAC9 histone deacetylase 9
HEATR3 HEAT repeat containing 3
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HLA-A major histocompatibility complex, class I, A
HLA-C major histocompatibility complex, class I, C
HMGA1 high mobility group AT-hook 1
HMGA2 high mobility group AT-hook 2
HPSE heparanase
ICAM1 intercellular adhesion molecule 1
IDO1 indoleamine 2,3-dioxygenase 1
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IL10 interleukin 10
IL17A interleukin 17A
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL5 interleukin 5
IL6 interleukin 6
INHA inhibin, alpha
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KCNH4 potassium channel, voltage gated eag related subfamily H, member 4
KCNH8 potassium channel, voltage gated eag related subfamily H, member 8
KDM2B lysine (K)-specific demethylase 2B
KIDINS220 kinase D-interacting substrate, 220kDa
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLHL34 kelch-like family member 34
KRT19 keratin 19, type I
KRT7 keratin 7, type II
LBH limb bud and heart development
LBR lamin B receptor
MAGEA1 melanoma antigen family A1
MAGEA4 melanoma antigen family A4
MAP2K7 mitogen-activated protein kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MB myoglobin
MBD2 methyl-CpG binding domain protein 2
MCM7 minichromosome maintenance complex component 7
MDK midkine (neurite growth-promoting factor 2)
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MED1 mediator complex subunit 1
MET MET proto-oncogene, receptor tyrosine kinase
MIB1 mindbomb E3 ubiquitin protein ligase 1
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MKI67 marker of proliferation Ki-67
MLH1 mutL homolog 1
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MSH3 mutS homolog 3
MSLN mesothelin
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUC1 mucin 1, cell surface associated
MUC4 mucin 4, cell surface associated
MUM1L1 melanoma associated antigen (mutated) 1-like 1
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NANS N-acetylneuraminic acid synthase
NCOA3 nuclear receptor coactivator 3
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NES nestin
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NGDN neuroguidin, EIF4E binding protein
NKX2-2 NK2 homeobox 2
NME1 NME/NM23 nucleoside diphosphate kinase 1
NR1I3 nuclear receptor subfamily 1, group I, member 3
NR4A3 nuclear receptor subfamily 4, group A, member 3
NUPR1 nuclear protein, transcriptional regulator, 1
OAT ornithine aminotransferase
PAEP progestagen-associated endometrial protein
PAX2 paired box 2
PAX3 paired box 3
PAX7 paired box 7
PAX8 paired box 8
PC pyruvate carboxylase
PCNA proliferating cell nuclear antigen
PDCD1 programmed cell death 1
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDZD4 PDZ domain containing 4
PIAS4 protein inhibitor of activated STAT, 4
PIEZO1 piezo-type mechanosensitive ion channel component 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLK1 polo-like kinase 1
PLS3 plastin 3
PMCH pro-melanin-concentrating hormone
POLDIP2 polymerase (DNA-directed), delta interacting protein 2
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRAME preferentially expressed antigen in melanoma
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRM3 protamine 3
PROM1 prominin 1
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTN pleiotrophin
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PUF60 poly-U binding splicing factor 60KDa
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAD23B RAD23 homolog B (S. cerevisiae)
RASAL3 RAS protein activator like 3
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBBP8 retinoblastoma binding protein 8
RBP4 retinol binding protein 4, plasma
REPS2 RALBP1 associated Eps domain containing 2
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPL34 ribosomal protein L34
S100A4 S100 calcium binding protein A4
SALL2 spalt-like transcription factor 2
SELE selectin E
SHCBP1 SHC SH2-domain binding protein 1
SIRT1 sirtuin 1
SIRT2 sirtuin 2
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SLC12A9 solute carrier family 12, member 9
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMN1 survival of motor neuron 1, telomeric
SMN2 survival of motor neuron 2, centromeric
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SNAI1 snail family zinc finger 1
SNAP23 synaptosomal-associated protein, 23kDa
SOX10 SRY (sex determining region Y)-box 10
SOX2 SRY (sex determining region Y)-box 2
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SS18 synovial sarcoma translocation, chromosome 18
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1
SS18L2 synovial sarcoma translocation gene on chromosome 18-like 2
SSX1 synovial sarcoma, X breakpoint 1
SSX2 synovial sarcoma, X breakpoint 2
SSX2B synovial sarcoma, X breakpoint 2B
SSX3 synovial sarcoma, X breakpoint 3
SSX4 synovial sarcoma, X breakpoint 4
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
SYCP1 synaptonemal complex protein 1
SYP synaptophysin
SYT1 synaptotagmin I
TAGLN transgelin
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAZ tafazzin
TBC1D25 TBC1 domain family, member 25
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFB1 transforming growth factor, beta 1
THBD thrombomodulin
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TLR3 toll-like receptor 3
TNF tumor necrosis factor
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TP53 tumor protein p53
TRIM13 tripartite motif containing 13
TSPAN31 tetraspanin 31
TSPYL2 TSPY-like 2
USP6 ubiquitin specific peptidase 6
VAMP3 vesicle-associated membrane protein 3
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A
VIM vimentin
VTCN1 V-set domain containing T cell activation inhibitor 1
YBX1 Y box binding protein 1
ZNF654 zinc finger protein 654