Synpolydactyly Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
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Genes

144 genes co-occuring with the disease Synpolydactyly in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
HOXD13 homeobox D13 3.655
HOXA13 homeobox A13 2.956
HOXD12 homeobox D12 2.664
HOXD11 homeobox D11 2.604
FBLN1 fibulin 1 2.538
EVX2 even-skipped homeobox 2 2.423
LMBR1 limb development membrane protein 1 2.381
HOXD9 homeobox D9 2.206
BHLHA9 basic helix-loop-helix family, member a9 2.144
GLI3 GLI family zinc finger 3 2.094
PABPN1 poly(A) binding protein, nuclear 1 2.09
ZP2 zona pellucida glycoprotein 2 (sperm receptor) 2.089
HOXD1 homeobox D1 2.051
HOXD8 homeobox D8 2.036
ZIC2 Zic family member 2 1.934
ARX aristaless related homeobox 1.927
SHH sonic hedgehog 1.885
FOXL2 forkhead box L2 1.842
HOXD4 homeobox D4 1.819
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 1.81
ATXN10 ataxin 10 1.787
HOXD3 homeobox D3 1.734
HOXA11 homeobox A11 1.696
RUNX2 runt-related transcription factor 2 1.683
EPHA7 EPH receptor A7 1.636
LNPK lunapark, ER junction formation factor 1.624
SOX3 SRY (sex determining region Y)-box 3 1.622
CSTB cystatin B (stefin B) 1.621
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 1.62
PHOX2B paired-like homeobox 2b 1.609
MSX2 msh homeobox 2 1.601
HAND2 heart and neural crest derivatives expressed 2 1.6
HOXC13 homeobox C13 1.588
IHH indian hedgehog 1.569
ZNF277 zinc finger protein 277 1.567
HOXD10 homeobox D10 1.554
PITX1 paired-like homeodomain 1 1.534
DRGX dorsal root ganglia homeobox 1.511
SAMD12 sterile alpha motif domain containing 12 1.507
COL26A1 collagen, type XXVI, alpha 1 1.495
SALL1 spalt-like transcription factor 1 1.494
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae) 1.482
TBP TATA box binding protein 1.461
FBLN2 fibulin 2 1.451
ADAMTSL2 ADAMTS-like 2 1.44
JPH3 junctophilin 3 1.438
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 1.428
AFF2 AF4/FMR2 family, member 2 1.426
IQCE IQ motif containing E 1.42
SHOX short stature homeobox 1.407
ATN1 atrophin 1 1.404
HOXA9 homeobox A9 1.391
TLX1 T-cell leukemia homeobox 1 1.388
HTT huntingtin 1.377
DMBX1 diencephalon/mesencephalon homeobox 1 1.371
ATXN7 ataxin 7 1.365
STARD7 StAR-related lipid transfer (START) domain containing 7 1.357
BBS9 Bardet-Biedl syndrome 9 1.348
PPP2R2B protein phosphatase 2, regulatory subunit B, beta 1.346
FXN frataxin 1.34
LRP12 low density lipoprotein receptor-related protein 12 1.333
AKAP8 A kinase (PRKA) anchor protein 8 1.331
CIAO3 cytosolic iron-sulfur assembly component 3 1.33
ARMC9 armadillo repeat containing 9 1.314
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20 1.292
SALL3 spalt-like transcription factor 3 1.284
HOXB1 homeobox B1 1.284
GDF5 growth differentiation factor 5 1.279
ZNF141 zinc finger protein 141 1.277
DLX2 distal-less homeobox 2 1.277
DLX1 distal-less homeobox 1 1.27
PAX9 paired box 9 1.263
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 1.263
RILPL1 Rab interacting lysosomal protein-like 1 1.263
CNBP CCHC-type zinc finger, nucleic acid binding protein 1.26
TSLIG3C tRNA splicing ligase complex subunit 3C 1.256
FBN2 fibrillin 2 1.255
NUP98 nucleoporin 98kDa 1.246
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 1.233
ATXN2 ataxin 2 1.231
GLI1 GLI family zinc finger 1 1.218
SFRP2 secreted frizzled-related protein 2 1.216
NOTCH2NLA notch 2 N-terminal like A 1.216
TWNK twinkle mtDNA helicase 1.214
TBX1 T-box 1 1.214
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila) 1.209
SOX9 SRY (sex determining region Y)-box 9 1.206
ATXN1 ataxin 1 1.204
ARHGAP31 Rho GTPase activating protein 31 1.202
DLX6 distal-less homeobox 6 1.189
NOTCH2NLC notch 2 N-terminal like C 1.184
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 1.181
GJA1 gap junction protein, alpha 1, 43kDa 1.177
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 1.175
TCF4 transcription factor 4 1.164
DMAP1 DNA methyltransferase 1 associated protein 1 1.159
PRKX protein kinase, X-linked 1.152
MSX1 msh homeobox 1 1.151
HOXB9 homeobox B9 1.147
MEIS1 Meis homeobox 1 1.139
ATXN3 ataxin 3 1.138
IFT57 intraflagellar transport 57 1.137
GMNN geminin, DNA replication inhibitor 1.134
HOXA7 homeobox A7 1.13
BMP4 bone morphogenetic protein 4 1.129
STKLD1 serine/threonine kinase-like domain containing 1 1.125
VAX1 ventral anterior homeobox 1 1.124
NOG noggin 1.123
HOXB2 homeobox B2 1.109
NEK4 NIMA-related kinase 4 1.107
FGF8 fibroblast growth factor 8 (androgen-induced) 1.106
ALX4 ALX homeobox 4 1.105
BRD4 bromodomain containing 4 1.104
C9ORF72 chromosome 9 open reading frame 72 1.099
CNTLN centlein, centrosomal protein 1.098
BBS10 Bardet-Biedl syndrome 10 1.091
ERI1 exoribonuclease 1 1.09
HMX2 H6 family homeobox 2 1.09
WNT7A wingless-type MMTV integration site family, member 7A 1.089
EN1 engrailed homeobox 1 1.087
UPK3A uroplakin 3A 1.08
PTCH1 patched 1 1.078
TP63 tumor protein p63 1.071
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 1.069
GLIS1 GLIS family zinc finger 1 1.068
FMR1 fragile X mental retardation 1 1.068
TBX4 T-box 4 1.067
DMPK dystrophia myotonica-protein kinase 1.054
FREM2 FRAS1 related extracellular matrix protein 2 1.053
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila) 1.05
LRRCC1 leucine rich repeat and coiled-coil centrosomal protein 1 1.05
DVL2 dishevelled segment polarity protein 2 1.05
SASS6 spindle assembly 6 homolog (C. elegans) 1.046
HOXA3 homeobox A3 1.041
ATP5MC3 ATP synthase membrane subunit c locus 3 1.038
BBS1 Bardet-Biedl syndrome 1 1.032
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase 1.031
HOXC8 homeobox C8 1.024
BBS2 Bardet-Biedl syndrome 2 1.021
DRD1 dopamine receptor D1 1.017
HMX3 H6 family homeobox 3 1.013
RPP25L ribonuclease P/MRP 25kDa subunit-like 1.011
SSPN sarcospan 1.01
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 1.0